Search Results - "Lv, Longbao"
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CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis
Published in Nature communications (17-07-2020)“…Circular RNAs (circRNAs) are abundant in mammalian brain and some show age-dependent expression patterns. Here, we report that circGRIA1, a conserved circRNA…”
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Perspective on using non-human primates in Exposome research
Published in Ecotoxicology and environmental safety (01-11-2024)“…The physiological and pathological changes in the human body caused by environmental pressures are collectively referred to as the Exposome. Human society is…”
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Annotation and cluster analysis of spatiotemporal- and sex-related lncRNA expression in rhesus macaque brain
Published in Genome research (01-09-2017)“…Long noncoding RNAs (lncRNAs) mediate important epigenetic regulation in a wide range of biological processes and diseases. We applied comprehensive analyses…”
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4
Maternal separation produces lasting changes in cortisol and behavior in rhesus monkeys
Published in Proceedings of the National Academy of Sciences - PNAS (23-08-2011)“…Maternal separation (MS), which can lead to hypothalamic pituitary adrenal axis dysfunction and behavioral abnormalities in rhesus monkeys, is frequently used…”
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5
A Fiber-Optic Sensor for Acoustic Emission Detection in a High Voltage Cable System
Published in Sensors (Basel, Switzerland) (30-11-2016)“…We have proposed and demonstrated a Michelson interferometer-based fiber sensor for detecting acoustic emission generated from the partial discharge (PD) of…”
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Shrew's venom quickly causes circulation disorder, analgesia and hypokinesia
Published in Cellular and molecular life sciences : CMLS (01-01-2022)“…Multiple representatives of eulipotyphlan mammals such as shrews have oral venom systems. Venom facilitates shrews to hunt and/or hoard preys. However, little…”
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Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype
Published in Neuroscience bulletin (01-09-2021)“…Whether direct manipulation of Parkinson’s disease (PD) risk genes in the adult monkey brain can elicit a Parkinsonian phenotype remains an unsolved issue…”
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Chronic clomipramine treatment reverses core symptom of depression in subordinate tree shrews
Published in PloS one (02-12-2013)“…Chronic stress is the major cause of clinical depression. The behavioral signs of depression, including anhedonia, learning and memory deficits, and sleep…”
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State‐specific Regulation of Electrical Stimulation in the Intralaminar Thalamus of Macaque Monkeys: Network and Transcriptional Insights into Arousal
Published in Advanced science (01-09-2024)“…Long‐range thalamocortical communication is central to anesthesia‐induced loss of consciousness and its reversal. However, isolating the specific neural…”
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10
Whole Genome Sequencing and Biological Characteristics of Two Strains of Porcine Escherichia coli Isolated from Saba Pigs
Published in Current microbiology (01-06-2022)“…Escherichia coli ( E. coli ) is an important pathogen that causes diarrhea and death in piglets. In this work, whole genome sequencing of two E. coli strains…”
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A Novel Tree Shrew Model of Chronic Experimental Autoimmune Uveitis and Its Disruptive Application
Published in Frontiers in immunology (27-05-2022)“…Background Previous studies have established several animal models for experimental autoimmune uveitis (EAU) in rodents without the fovea centralis in the…”
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12
Gene editing in monogenic autism spectrum disorder: animal models and gene therapies
Published in Frontiers in molecular neuroscience (14-12-2022)“…Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disease, and its diagnosis is dependent on behavioral manifestation, such as impaired…”
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13
Lumbar puncture increases Alzheimer’s disease biomarker levels in cerebrospinal fluid of rhesus monkeys
Published in iScience (19-04-2024)“…Cerebrospinal fluid (CSF) samples are commonly collected via lumbar puncture (LP) in both clinical and research settings for measurement of biomarkers of…”
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14
A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal
Published in Disease models & mechanisms (15-04-2019)“…Pancreatic cancer is one of the most lethal common cancers. The cell of origin of pancreatic ductal adenocarcinoma (PDAC) has been controversial, and recent…”
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Transferrin Is Up-Regulated by Microbes and Acts as a Negative Regulator of Immunity to Induce Intestinal Immunotolerance
Published in Research (Washington) (2024)“…Cross-talks (e.g., host-driven iron withdrawal and microbial iron uptake between host gastrointestinal tract and commensal microbes) regulate immunotolerance…”
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New insights into the construction of wild-type Saba pig-derived Escherichia coli irp2 gene deletion strains
Published in 3 Biotech (01-09-2021)“…To construct wild-type E. coli irp2 gene deletion strains, CRISPR/Cas9 gene editing technology was used, and the difficulty and key points of gene editing of…”
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True Phase Measurement of Distributed Vibration Sensors Based on Heterodyne \varphi -OTDR
Published in IEEE photonics journal (01-02-2018)“…We demonstrate a method to truly measure the phase change originated from external vibration by heterodyne phase-sensitive optical time-domain reflectometer…”
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Establishment of Hematological and Serum Biochemical Parameters in 4,834 Healthy Cynomolgus Monkeys (Macaca fascicularis)
Published in BIO Integration (Online) (2022)“…Abstract Background: In China and other countries, cynomolgus monkeys are commonly used experimental animal models in biomedical research. Reference…”
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Human β-Defensin 2 Is a Novel Opener of Ca2+-Activated Potassium Channels and Induces Vasodilation and Hypotension in Monkeys
Published in Hypertension (Dallas, Tex. 1979) (01-08-2013)“…Human β-defensin 2 (HBD2) is a cysteine-rich cationic antimicrobial peptide known for its important role in innate immune system. Intensive studies have…”
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Fast coarse-fine locating method for φ-OTDR
Published in Optics express (05-02-2018)“…We proposed and demonstrated a coarse-fine method to achieve fast locating of external vibration for the phase-sensitive optical time-domain reflectometer…”
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