Search Results - "Lv, Kangjie"

Genome-Based Discovery of Enantiomeric Pentacyclic Sesterterpenes Catalyzed by Fungal Bifunctional Terpene Synthases by Jiang, Lan, Zhang, Xue, Sato, Yuya, Zhu, Guoliang, Minami, Atsushi, Zhang, Weiyan, Ozaki, Taro, Zhu, Bin, Wang, Zhixin, Wang, Xinye, Lv, Kangjie, Zhang, Jingyu, Wang, Yongheng, Gao, Shushan, Liu, Chengwei, Hsiang, Tom, Zhang, Lixin, Oikawa, Hideaki, Liu, Xueting

“…Genome-based discovery of two previously unreported fungal bifunctional terpene synthases (BFTSs) from phytopathogenic fungi are reported: FoFS catalyzing the…”
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Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi by Jiang, Lan, Zhu, Guoliang, Han, Jianying, Hou, Chengjian, Zhang, Xue, Wang, Zhixin, Yuan, Weize, Lv, Kangjie, Cong, Zhanren, Wang, Xinye, Chen, Xiangyin, Karthik, Loganathan, Yang, Huanting, Wang, Xuyuan, Tan, Gaoyi, Liu, Guang, Zhao, Liya, Xia, Xuekui, Liu, Xiangyang, Gao, Shushan, Ma, Lei, Liu, Mei, Ren, Biao, Dai, Huanqin, Quinn, Ronald J., Hsiang, Tom, Zhang, Jingyu, Zhang, Lixin, Liu, Xueting

“…Fungal terpenoids catalyzed by bifunctional terpene synthases (BFTSs) possess interesting bioactive and chemical properties. In this study, an integrated…”
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Expanding catalytic promiscuity of a bifunctional terpene synthase through a single mutation-induced change in hydrogen-bond network within the catalytic pocket by Wang, Xinye, Huang, Yiyi, Zhang, Weiyan, Lv, Kangjie, Li, Xiaoying, Wang, Zhixin, Zhang, Li, Hsiang, Tom, Zhang, Lixin, Ouyang, Liming, Liu, Xueting

“…Fungal bifunctional terpene synthases (BFTSs) catalyze the formation of numerous di-/sester-/tri-terpenes skeletons. However, the mechanism in controlling the…”
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Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing by Jiang, Lan, Zhang, Tianji, Lu, Hongzhong, Li, Saijuan, Lv, Kangjie, Tuffour, Alex, Zhang, Lixin, Ding, Kan, Li, Jin-Ping, Li, Hongmei, Liu, Xueting

“…The COVID-19 pandemic has caused severe health problems worldwide and unprecedented decimation of the global economy. Moreover, after more than 2 years, many…”
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Norditerpenoids biosynthesized by variediene synthase-associated P450 machinery along with modifications by the host cell Aspergillus oryzae by Jiang, Lan, Lv, Kangjie, Zhu, Guoliang, Lin, Zhi, Zhang, Xue, Xing, Cuiping, Yang, Huanting, Zhang, Weiyan, Wang, Zhixin, Liu, Chengwei, Qu, Xudong, Hsiang, Tom, Zhang, Lixin, Liu, Xueting

“…The chemical diversity of terpenoids is typically established by terpene synthase-catalyzed cyclization and diversified by post-tailoring modifications. Fungal…”
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Recent advances in biotechnology for marine enzymes and molecules by Zhang, Jingyu, Jiang, Lan, Chen, Xiangyin, Lv, Kangjie, Basiony, Mostafa, Zhu, Guoliang, Karthik, Loganathan, Ouyang, Liming, Zhang, Lixin, Liu, Xueting

“…The marine environment is the most biologically and chemically diverse habitat on Earth, and provides numerous marine-derived products, including enzymes and…”
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Identifying sesterterpenoids via feature-based molecular networking and small-scale fermentation by Lv, Kangjie, Duan, Yuyang, Li, Xiaoying, Wang, Xinye, Xing, Cuiping, Lan, Keying, Zhu, Bin, Zhu, Guoliang, Qiu, Yuyang, Li, Songwei, Hsiang, Tom, Zhang, Lixin, Jiang, Lan, Liu, Xueting

“…Terpenoids are known for their diverse structures and broad bioactivities with significant potential in pharmaceutical applications. However, natural products…”
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Schultriene and nigtetraene: two sesterterpenes characterized from pathogenetic fungi via genome mining approach by Jiang, Lan, Yang, Huanting, Zhang, Xue, Li, Xiaoying, Lv, Kangjie, Zhang, Weiyan, Zhu, Guoliang, Liu, Chengwei, Wang, Yongheng, Hsiang, Tom, Zhang, Lixin, Liu, Xueting

“…Fungal bifunctional terpene synthases (BFTSs) have been reported to contribute to the biosynthesis of a variety of di/sesterterpenes via different carbocation…”
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Molecular networking assisted discovery and biosynthesis elucidation of the antimicrobial spiroketals epicospirocins by Zhu, Guoliang, Hou, Chengjian, Yuan, Weize, Wang, Zhenzhen, Zhang, Jingyu, Jiang, Lan, Karthik, Loganathan, Li, Bixiao, Ren, Biao, Lv, Kangjie, Lu, Wanying, Cong, Zhanren, Dai, Huanqin, Hsiang, Tom, Zhang, Lixin, Liu, Xueting

“…Two pairs of dibenzospiroketal racemates, (±)-epicospirocin A (1a/1b) and (±)-1-epi-epicospirocin A (2a/2b), and two (+)-enantiomers of aspermicrones,…”
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