Search Results - "Lv, Dongming"

M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression by Lv, Dongming, Ding, Shirong, Zhong, Li, Tu, Jian, Li, Hongbo, Yao, Hao, Zou, Yutong, Zeng, Ziliang, Liao, Yan, Wan, Xuesi, Wen, Lili, Xie, Xianbiao

“…Despite advances in clinical diagnosis and treatment, the prognosis of patients with osteosarcoma (OS) remains poor, and the treatment efficacy has plateaued…”
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Transcriptome profiles of fatty acid metabolism-related genes and immune infiltrates identify hot tumors for immunotherapy in cutaneous melanoma by Dong, Yunxian, Zhao, Zirui, Simayi, Maijimi, Chen, Chufen, Xu, Zhongye, Lv, Dongming, Tang, Bing

“…Background: Immunotherapy with checkpoint inhibitors usually has a low response rate in some cutaneous melanoma (CM) cases due to its cold nature. Hence,…”
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Comprehensive metabolomic profiling of osteosarcoma based on UHPLC-HRMS by Lv, Dongming, Zou, Yutong, Zeng, Ziliang, Yao, Hao, Ding, Shirong, Bian, Yiying, Wen, Lili, Xie, Xianbiao

“…Introduction Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. An increasing number of studies have demonstrated…”
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NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts by Dong, Yunxian, Wang, Haibin, Zhang, Youliang, Wu, Yanqun, Lu, Ling, Yu, Hao, Zhou, Lingcong, Zhao, Peng, Ouyang, Sixue, Song, Zibin, Hu, Zhicheng, Lv, Dongming, Rong, Yanchao, Zhao, Zirui, Tao, Jia, Tang, Bing, Luo, Shengkang

“…The hypertrophic scar (HS) is a prevalent cutaneous fibrotic disorder that impacts both the aesthetic and functional aspects of the skin, there is an urgent…”
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Single-stage transplantation combined with epidermal stem cells promotes the survival of tissue-engineered skin by inducing early angiogenesis by Wang, Zhiyong, Xu, Hailin, Yang, Hao, Zhang, Yi, Wang, Xiaoyan, Wang, Peng, Xu, Zhongye, Lv, Dongming, Rong, Yanchao, Dong, Yunxian, Tang, Bing, Hu, Zhicheng, Deng, Wuguo, Zhu, Jiayuan

“…The composite transplantation of a split-thickness skin graft (STSG) combined with an acellular dermal matrix (ADM) is a promising repair method for…”
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Skin Microbiota, Immune Cell, and Skin Fibrosis: A Comprehensive Mendelian Randomization Study by Zhao, Zirui, Rong, Yanchao, Yin, Rong, Zeng, Ruixi, Xu, Zhongye, Lv, Dongming, Hu, Zhicheng, Cao, Xiaoling, Tang, Bing

“…Microbiota dysbiosis has been reported to lead to leaky epithelia and trigger numerous dermatological conditions. However, potential causal associations…”
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Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis by Dong, Yunxian, Lv, Dongming, Zhao, Zirui, Xu, Zhongye, Hu, Zhicheng, Tang, Bing

“…Hypertrophic scar (HS) is a fibrotic cutaneous disease with few effective therapies. Lycorine is a drug with pro-apoptotic ability and anti-fibrosis potential…”
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DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway by Ding, Shirong, Gao, Ying, Lv, Dongming, Tao, Yalan, Liu, Songran, Chen, Chen, Huang, Zilu, Zheng, Shuohan, Hu, Yujun, Chow, Larry Ka-Yue, Wei, Yinghong, Feng, Ping, Dai, Wei, Wang, Xin, Xia, Yunfei

“…Distant metastasis remains the leading cause of treatment failure in patients with nasopharyngeal carcinoma (NPC), making it critical to identify efficient…”
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Impact of the gut microbiome on skin fibrosis: a Mendelian randomization study by Zhao, Zirui, Xu, Zhongye, Lv, Dongming, Rong, Yanchao, Hu, Zhicheng, Yin, Rong, Dong, Yunxian, Cao, Xiaoling, Tang, Bing

“…Skin fibrosis is a lesion in the dermis causing to itching, pain, and psychological stress. The gut microbiome plays as an essential role in skin diseases…”
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Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis by Zou, Yutong, Guo, Siyao, Wen, Lili, Lv, Dongming, Tu, Jian, Liao, Yan, Chen, Weidong, Chen, Ziyun, Li, Hongbo, Chen, Junkai, Shen, Jingnan, Xie, Xianbiao

“…Despite advances in treatment, the prognosis of patients with osteosarcoma remains unsatisfactory, and searching for potential targets is imperative. Here, we…”
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Augmenting L3MBTL2-induced condensates suppresses tumor growth in osteosarcoma by Zhong, Li, Wang, Jingxuan, Chen, Wanqi, Lv, Dongming, Zhang, Ruhua, Wang, Xin, Zeng, Cuiling, He, Xiaobo, Zheng, Lisi, Gao, Ying, Wang, Shang, Li, Miao, Wu, Yuanzhong, Yin, Junqiang, Kang, Tiebang, Liao, Dan

“…Osteosarcoma is a highly aggressive cancer and lacks effective therapeutic targets. We found that L3MBTL2 acts as a tumor suppressor by transcriptionally…”
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Multimodal Risk-Adapted Treatment in Surgical Patients With Synovial Sarcoma: A Preoperative Nomogram-Guided Adjuvant Treatment Strategy by Zeng, Ziliang, Yao, Hao, Lv, Dongming, Jin, Qinglin, Bian, Yiying, Zou, Yutong, Tu, Jian, Wang, Bo, Wen, Lili, Xie, Xianbiao

“…Synovial sarcoma is characterized by heterogeneous clinical manifestations, making it difficult to evaluate individual patients' prognoses and design personal…”
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GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing by Dong, Yunxian, Zhang, Youliang, Li, Fangwei, Tang, Bing, Lv, Dongming, Wang, Haibin, Luo, Shengkang

“…Adipose-derived stem cells (ADSCs) have been proven to promote healing in diabetic wounds, which are one of the most serious chronic refractory wounds…”
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Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling by Dong, Yunxian, Cao, Xiaoling, Huang, Jinsheng, Hu, Zhicheng, Chen, Chufen, Chen, Miao, Long, Qian, Xu, Zhongye, Lv, Dongming, Rong, Yanchao, Luo, Shengkang, Wang, Haibin, Deng, Wuguo, Tang, Bing

“…Hypertrophic scar (HS) is a fibrotic skin condition and characterized by abnormal proliferation of myofibroblasts and accumulation of extracellular matrix…”
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Analysis of miR-203a-3p/SOCS3-mediated induction of M2 macrophage polarization to promote diabetic wound healing based on epidermal stem cell-derived exosomes by Yang, Hao, Xu, Hailin, Wang, Zhiyong, Li, Xiaohui, Wang, Peng, Cao, Xiaoling, Xu, Zhongye, Lv, Dongming, Rong, Yanchao, Chen, Miao, Tang, Bing, Hu, Zhicheng, Deng, Wuguo, Zhu, Jiayuan

“…The development of therapeutic strategies to improve wound healing in individual diabetic patients remains challenging. Stem cell-derived exosomes represent a…”
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Low-frequency axial vibration drilling of Al2O3/GFRP laminated composite plate by diamond trepanning bit by Zheng, Lei, Qin, Peng, Lv, Dongming, Wei, Wendong, Dong, Xianglong, Park, Sanghu

“…In armor protection fields, various ceramics/FRP laminated composite plates are increasingly applied because of superior comprehensive protection performances…”
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EBF3 reactivation by inhibiting the EGR1/EZH2/HDAC9 complex promotes metastasis via transcriptionally enhancing vimentin in nasopharyngeal carcinoma by Ding, Shirong, Wang, Xin, Lv, Dongming, Tao, Yalan, Liu, Songran, Chen, Chen, Huang, Zilu, Zheng, Shuohan, Wei, Yinghong, Kang, Tiebang, Xia, Yunfei

“…Metastasis is the major reason for treatment failure and accounts for cancer-related death in patients with nasopharyngeal carcinoma. However, the genetic…”
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Up-regulation of PCOLCE by TWIST1 promotes metastasis in Osteosarcoma by Wang, Shang, Zhong, Li, Li, Yin, Xiao, Desheng, Zhang, Ruhua, Liao, Dan, Lv, Dongming, Wang, Xin, Wang, Juanfei, Xie, Xianbiao, Chen, Jing, Wu, Yuanzhong, Kang, Tiebang

“…Procollagen C-proteinase enhancer protein (PCOLCE) was originally identified as an enhancer to facilitate the catalysis of procollagens by BMP1. PCOLCE…”
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The naringin/carboxymethyl chitosan/sodium hyaluronate/silk fibroin scaffold facilitates the healing of diabetic wounds by restoring the ROS-related dysfunction of vascularization and macrophage polarization by Yang, Hao, Xu, Hailin, Lv, Dongming, Li, Shuting, Rong, Yanchao, Wang, Zhiyong, Wang, Peng, Cao, Xiaoling, Li, Xiaohui, Xu, Zhongye, Tang, Bing, Zhu, Jiayuan, Hu, Zhicheng

“…Chronic diabetic wounds remain a globally recognized clinical challenge, which occurs mainly due to the disturbances of wound microenvironmental induced by…”
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Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing by Lv, Dongming, Cao, Xiaoling, Zhong, Li, Dong, Yunxian, Xu, Zhongye, Rong, Yanchao, Xu, Hailin, Wang, Zhiyong, Yang, Hao, Yin, Rong, Chen, Miao, Ke, Chao, Hu, Zhicheng, Deng, Wuguo, Tang, Bing

“…Moderate inflammation is essential for standard wound healing. In pathological conditions, such as diabetes, protracted and refractory wounds are associated…”
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