Search Results - "Luzung, Michael R"

Biphilic Organophosphorus-Catalyzed Intramolecular Csp2 –H Amination: Evidence for a Nitrenoid in Catalytic Cadogan Cyclizations by Nykaza, Trevor V, Ramirez, Antonio, Harrison, Tyler S, Luzung, Michael R, Radosevich, Alexander T

“…A small-ring phospha­cyclo­alkane (1,2,2,3,4,4-hexa­methyl­phosphetane, 3) catalyzes intramolecular C–N bond forming heterocyclization of o-nitrobiaryl and…”
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An Improved PIII/PVO-Catalyzed Reductive C–N Coupling of Nitroaromatics and Boronic Acids by Mechanistic Differentiation of Rate- and Product-Determining Steps by Li, Gen, Nykaza, Trevor V, Cooper, Julian C, Ramirez, Antonio, Luzung, Michael R, Radosevich, Alexander T

“…Experimental, spectroscopic, and computational studies are reported that provide an evidence-based mechanistic description of an intermolecular reductive C–N…”
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Gold-Catalyzed Cycloisomerization of 1,5-Allenynes via Dual Activation of an Ene Reaction by Cheong, Paul Ha-Yeon, Morganelli, Philip, Luzung, Michael R, Houk, K. N, Toste, F. Dean

“…Tris(triphenylphosphinegold) oxonium tetrafluoroborate, [(Ph3PAu)3O]BF4, catalyzes the rearrangement of 1,5-allenynes to produce cross-conjugated trienes…”
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Direct, Chemoselective N-tert-Prenylation of Indoles by C----H Functionalization by Luzung, Michael R, Lewis, Chad A, Baran, Phil S

“…Four steps in one: The direct prenylation of indoles at N‐1 can be achieved by CH functionalization in the presence of a PdII source. This reaction proceeds…”
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A Mild Negishi Cross-Coupling of 2-Heterocyclic Organozinc Reagents and Aryl Chlorides by Luzung, Michael R, Patel, Jigar S, Yin, Jingjun

“…A mild Negishi cross-coupling of 2-heterocyclic organozinc reagents and aryl chlorides is described. The use of Pd2(dba)3 and X-Phos as a ligand provides high…”
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Catalaytic Isomerization of 1,5-Enynes to Bicyclo[3.1.0]hexenes by Luzung, Michael R, Markham, Jordan P, Toste, F. Dean

“…The cycloisomerization of 1,5-enynes catalyzed by cationic triphenylphosphinegold(I) complexes produces bicyclo[3.1.0]hexenes. Substitution at all positions of…”
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PIII/PV=O Catalyzed Cascade Synthesis of N‐Functionalized Azaheterocycles by Nykaza, Trevor V., Li, Gen, Yang, Junyu, Luzung, Michael R., Radosevich, Alexander T.

“…An organocatalytic method for the modular synthesis of diverse N‐aryl and N‐alkyl azaheterocycles (indoles, oxindoles, benzimidazoles, and quinoxalinediones)…”
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Rhenium-Catalyzed Coupling of Propargyl Alcohols and Allyl Silanes by Luzung, Michael R, Toste, F. Dean

“…A mild method for the regioselective coupling of propargyl alcohols and allylsilanes is described. The method employs an air- and moisture-tolerant rhenium-oxo…”
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Stereoselective Synthesis of Vinylsilanes by a Gold(I)-Catalyzed Acetylenic Sila-Cope Rearrangement by Horino, Yoshikazu, Luzung, Michael R, Toste, F. Dean

“…Cationic tri-tert-butylphosphinegold(I) serves as a catalyst in the sila-Cope rearrangement of acetylenic allylsilanes. When phenol is employed as a…”
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Functional Characterization of the Cyclomarin/Cyclomarazine Prenyltransferase CymD Directs the Biosynthesis of Unnatural Cyclic Peptides by Schultz, Andrew W, Lewis, Chad A, Luzung, Michael R, Baran, Phil S, Moore, Bradley S

“…In vitro and in vivo characterization of the cyclomarin/cyclomarazine prenyltransferase CymD revealed its ability to prenylate tryptophan prior to…”
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Intermolecular Reductive C-N Cross Coupling of Nitroarenes and Boronic Acids by P III /P V ═O Catalysis by Nykaza, Trevor V, Cooper, Julian C, Li, Gen, Mahieu, Nolwenn, Ramirez, Antonio, Luzung, Michael R, Radosevich, Alexander T

“…A main group-catalyzed method for the synthesis of aryl- and heteroarylamines by intermolecular C-N coupling is reported. The method employs a small-ring…”
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P III /P V =O Catalyzed Cascade Synthesis of N-Functionalized Azaheterocycles by Nykaza, Trevor V, Li, Gen, Yang, Junyu, Luzung, Michael R, Radosevich, Alexander T

“…An organocatalytic method for the modular synthesis of diverse N-aryl and N-alkyl azaheterocycles (indoles, oxindoles, benzimidazoles, and quinoxalinediones)…”
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Gold(I)-Catalyzed [2 + 2]-Cycloaddition of Allenenes by Luzung, Michael R, Mauleón, Pablo, Toste, F. Dean

“…A cationic phosphinegold(I)-catalyzed intramolecular [2 + 2]-cycloaddition between an allene and an alkene to form alkylidene−cyclobutanes is described…”
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An Improved P III /P V ═O-Catalyzed Reductive C-N Coupling of Nitroaromatics and Boronic Acids by Mechanistic Differentiation of Rate- and Product-Determining Steps by Li, Gen, Nykaza, Trevor V, Cooper, Julian C, Ramirez, Antonio, Luzung, Michael R, Radosevich, Alexander T

“…Experimental, spectroscopic, and computational studies are reported that provide an evidence-based mechanistic description of an intermolecular reductive C-N…”
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Biphilic Organophosphorus-Catalyzed Intramolecular C sp 2 -H Amination: Evidence for a Nitrenoid in Catalytic Cadogan Cyclizations by Nykaza, Trevor V, Ramirez, Antonio, Harrison, Tyler S, Luzung, Michael R, Radosevich, Alexander T

“…A small-ring phosphacycloalkane (1,2,2,3,4,4-hexamethylphosphetane, 3) catalyzes intramolecular C-N bond forming heterocyclization of o-nitrobiaryl and…”
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Intermolecular Reductive C–N Cross Coupling of Nitroarenes and Boronic Acids by PIII/PVO Catalysis by Nykaza, Trevor V, Cooper, Julian C, Li, Gen, Mahieu, Nolwenn, Ramirez, Antonio, Luzung, Michael R, Radosevich, Alexander T

“…A main group-catalyzed method for the synthesis of aryl- and heteroarylamines by intermolecular C–N coupling is reported. The method employs a small-ring…”
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Nitration Using Fuming HNO3 in Sulfolane: Synthesis of 6‑Nitrovanillin in Flow Mode by Rakshit, Souvik, Lakshminarasimhan, Thirumalai, Guturi, Sivakrishna, Kanagavel, Kishorekumar, Kanusu, Umamaheswara Rao, Niyogi, Ankita G, Sidar, Somprabha, Luzung, Michael R, Schmidt, Michael A, Zheng, Bin, Eastgate, Martin D, Vaidyanathan, Rajappa

“…We report herein an improved synthesis of 6-nitrovanillin, an important building block used in pharmaceuticals and agrochemicals. The key step in this sequence…”
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A Mild, Functional Group Tolerant Addition of Organozinc Nucleophiles to N‑Activated Quinolines and Isoquinolines by Luzung, Michael R, Dixon, Darryl D, Ortiz, Adrian, Guerrero, Carlos A, Ayers, Sloan, Ho, Jeanne, Schmidt, Michael A, Strotman, Neil A, Eastgate, Martin D

“…An addition of organozinc nucleophiles to N-acyl activated quinolines and isoquinolines is described. Simple transmetalation with the corresponding Grignard…”
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DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody–Drug Conjugate Modality by Sivaprakasam, Prasanna, McDonald, Ivar, Iwuagwu, Christiana, Chowdari, Naidu S, Peese, Kevin M, Langley, David R, Cheng, Heng, Luzung, Michael R, Schmidt, Michael A, Zheng, Bin, Tan, Yichen, Cho, Patricia, Rakshit, Souvik, Lakshminarasimhan, Thirumalai, Guturi, Sivakrishna, Kanagavel, Kishorekumar, Kanusu, Umamaheswararao, Niyogi, Ankita G, Sidhar, Somprabha, Vaidyanathan, Rajappa, Eastgate, Martin D, Kotapati, Srikanth, Deshpande, Madhura, Pan, Chin, Cardarelli, Pina M, Xie, Chunshan, Rao, Chetana, Holder, Patrick, Sarma, Ganapathy, Vite, Gregory, Gangwar, Sanjeev

“…A new series with the tetrahydroisoquinoline-fused benzodiazepine (TBD) ring system combined with the surrogates of (1-methyl-1H-pyrrol-3-yl)­benzene (“MPB”)…”
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PIII/PV=O Catalyzed Cascade Synthesis of N‐Functionalized Azaheterocycles by Nykaza, Trevor V., Li, Gen, Yang, Junyu, Luzung, Michael R., Radosevich, Alexander T.

“…An organocatalytic method for the modular synthesis of diverse N‐aryl and N‐alkyl azaheterocycles (indoles, oxindoles, benzimidazoles, and quinoxalinediones)…”
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