Search Results - "Luz, Nívea Farias"
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Leishmania infantum lipophosphoglycan induced-Prostaglandin E2 production in association with PPAR-γ expression via activation of Toll like receptors-1 and 2
Published in Scientific reports (30-10-2017)“…Lipophosphoglycan (LPG) is a key virulence factor expressed on the surfaces of Leishmania promastigotes. Although LPG is known to activate macrophages, the…”
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2
Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burden in neutrophils
Published in Journal of leukocyte biology (01-09-2011)“…Salivary proteins from Lutzomyia longipalpis induce host neutrophil caspase‐dependent apoptosis and infection by Leishmania chagasi. Neutrophils are considered…”
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3
The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages
Published in The Journal of immunology (1950) (01-01-2016)“…The cytokine IL-1β is intimately linked to many pathological inflammatory conditions. Mature IL-1β secretion requires cleavage by the inflammasome. Recent…”
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4
RIPK1 and PGAM5 Control Leishmania Replication through Distinct Mechanisms
Published in The Journal of immunology (1950) (15-06-2016)“…Leishmaniasis is an important parasitic disease found in the tropics and subtropics. Cutaneous and visceral leishmaniasis affect an estimated 1.5 million…”
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5
Programmed Necrosis in the Cross Talk of Cell Death and Inflammation
Published in Annual review of immunology (21-03-2015)“…Cell proliferation and cell death are integral elements in maintaining homeostatic balance in metazoans. Disease pathologies ensue when these processes are…”
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Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin
Published in Frontiers in immunology (17-07-2020)“…The excessive release of heme during hemolysis contributes to the severity of sickle cell anemia (SCA) by exacerbating hemoglobin S (HbS) autoxidation,…”
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Proteomic Analysis Reveals a Predominant NFE2L2 (NRF2) Signature in Canonical Pathway and Upstream Regulator Analysis of Leishmania -Infected Macrophages
Published in Frontiers in immunology (28-06-2019)“…CBA mice macrophages (MØ) control infection by and are susceptive to , suggesting that both parasite species induce distinct responses that play important…”
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Hydroxyurea Exhibits Antioxidant Activity Via the Nrf2 Pathway- Antioxidant/Electrophile Response Element Regulated By p62/ SQSTM1
Published in Blood (29-11-2018)“…Introduction: The pathophysiology of sickle cell anemia (HF) is characterized by hemolytic and intermittent vasoconstrictive events with increased redox status…”
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Sickle Cell Inflammatory Environment Is Associated with Products of the Eicosanoid Synthesis Pathways
Published in Blood (03-12-2015)“…Background: Sickle cell disease (SCD) is a group of inherited anemia characterized by heterogeneous clinical outcome, including hemolysis, chronic…”
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10
Heme Concentration As a Biomarker of Sickle Cell Disease Severity: Its Role in Steady-State and in Crisis Patients
Published in Blood (03-12-2015)“…Background: Sickle cell disease (SCD) is a heredity group of anemia characterized by hemolysis, chronic inflammation, and vaso-occlusive/painful crisis. The…”
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11
Leishmania infantum lipophosphoglycan induced-Prostaglandin E 2 production in association with PPAR-γ expression via activation of Toll like receptors-1 and 2
Published in Scientific reports (30-10-2017)“…Lipophosphoglycan (LPG) is a key virulence factor expressed on the surfaces of Leishmania promastigotes. Although LPG is known to activate macrophages, the…”
Get full text
Journal Article