Search Results - "Luyt, L. G"

Molecular imaging probes derived from natural peptides by Charron, C L, Hickey, J L, Nsiama, T K, Cruickshank, D R, Turnbull, W L, Luyt, L G

“…Covering: up to the end of 2015.Peptides are naturally occurring compounds that play an important role in all living systems and are responsible for a range of…”
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Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis by Bahrami, S. B, Tolg, C, Peart, T, Symonette, C, Veiseh, M, Umoh, J. U, Holdsworth, D. W, McCarthy, J. B, Luyt, L. G, Bissell, M. J, Yazdani, A, Turley, E. A

“…Hyaluronan, CD44 and the Receptor for Hyaluronan-Mediated Motility (RHAMM, gene name HMMR) regulate stem cell differentiation including mesenchymal progenitor…”
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In vivo multimodal imaging of hyaluronan-mediated inflammatory response in articular cartilage by Ruiz, A., Duarte, A., Bravo, D., Ramos Gavilá, E., Zhang, C., Cowman, M.K., Kirsch, T., Milne, M., Luyt, L.G., Raya, J.G.

“…One driving factor in the progression to posttraumatic osteoarthritis (PTOA) is the perpetuation of the inflammatory response to injury into chronic…”
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The development of a near infrared inulin optical probe for measuring glomerular filtration rate by Hauser-Kawaguchi, A., Milne, M., Li, F., Lee, T.Y., Luyt, L.G.

“…The polysaccharide, inulin, is considered the clinical gold standard for measuring glomerular filtration rate (GFR), an assessment of kidney filtering capacity…”
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Development of a [ 68 Ga]-ghrelin analogue for PET imaging of the ghrelin receptor (GHS-R1a) by Charron, C L, McFarland, M S, Dhanvantari, S, Luyt, L G

“…The ghrelin receptor is a member of the growth hormone secretagogue receptor (GHS-R) family and is present at low concentrations in tissues such as the brain,…”
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Development of a [68Ga]-ghrelin analogue for PET imaging of the ghrelin receptor (GHS-R1a)Electronic supplementary information (ESI) available: HPLC chromatograms, radiolabelling scheme, radiolabelling optimization details. See DOI: 10.1039/c8md00210j by Charron, C. L, McFarland, M. S, Dhanvantari, S, Luyt, L. G

“…The ghrelin receptor is a member of the growth hormone secretagogue receptor (GHS-R) family and is present at low concentrations in tissues such as the brain,…”
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A Trithiolate Tripodal Bifunctional Ligand for the Radiolabeling of Peptides with Gallium(III) by Luyt, Leonard G., Katzenellenbogen, John A.

“…A tripodal bifunctional chelator for gallium has been prepared with a chelation core consisting of three thiols and a tertiary amine. The synthesis proceeds in…”
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Single Isomer Technetium-99m Tamoxifen Conjugates by Hunter, Duncan H, Luyt, Leonard G

“…To produce an imaging agent for breast cancer using a technetium-99m-labeled agent specific for estrogen receptors, an N2S2 bifunctional chelator was…”
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An N2S2 Bifunctional Chelator for Technetium-99m and Rhenium:  Complexation, Conjugation, and Epimerization to a Single Isomer by Luyt, Leonard G, Jenkins, Hilary A, Hunter, Duncan H

“…A bifunctional chelator 6 was prepared bearing an N2S2 core for binding rhenium or technetium and a carboxylic acid group for conjugation to amino groups of…”
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A truncated RHAMM protein for discovering novel therapeutic peptides by Hauser-Kawaguchi, Alexandra, Tolg, Cornelia, Peart, Teresa, Milne, Mark, Turley, Eva A., Luyt, Leonard G.

“…[Display omitted] •7 kDa RHAMM is a chemically synthesized, truncated receptor of native 95 kDa RHAMM.•7 kDa RHAMM is biologically active and can be…”
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Synthesis of a functionalized gallium(III) tripodyl complex by Luyt, L. G., Katzenellenbogen, J. A.

“…A NS3 tetradentate gallium(III) complex bearing an amine functionality has been synthesized, and it has been derivatized with various peptides…”
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Design and Synthesis of Functionalized Cyclopentadienyl Tricarbonylmetal Complexes for Technetium-94m PET Imaging of Estrogen Receptors by Bigott, Heather M, Parent, Ephraim, Luyt, Leonard G, Katzenellenbogen, John A, Welch, Michael J

“…Cyclopentadienyl tricarbonylmetal (CpTM, M = Re, 94mTc) complexes, some based on a typical nonsteroidal estrogen, were prepared with the aim of developing…”
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Preparation of cyclopentadienyl tricarbonyl technetium-94m complexes by Luyt, L. G., Mull, E. S., Katzenellenbogen, J. A., Bigott, H. M., Welch, M. J.

“…Cyclopentadienyltricarbonyl complexes with technetium‐94m have been prepared by two methods and were characterized by comparison to rhenium analogues…”
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New dithiocarbamato-carboxylate chelation units for linking M(CO)3+ (M = Tc, Re) species to other molecules by Gorshkov, N. I., Katzenellenbogen, J. A., Luyt, L. G., Lumpov, A. A., Miroslavov, A. E., Suglobov, D. N.

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“Scorpion-like” dithiocarbamato-carboxylate ligands for linking M(CO)3 + (M=Tc, Re) by Gorshkov, N. I., Lumpov, A. A., Miroslavov, A. E., Suglobov, D. N., Katzenellenbogen, J. A., Luyt, L. G.

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Lysine conjugates for the labelling of peptides with technetium-99m and rhenium by Hunter, Duncan H., Luyt, Leonard G.

“…A novel method of preparing 99mTc labelled peptides, through the incorporation of a lysine analogue containing a metal chelation centre, is proposed…”
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