Search Results - "Lux, MP"

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    A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer by Michailidou, Kyriaki, Lu, Yingchang, Cai, Qiuyin, Rozali, Esdy, Li, Bingshan, Barfield, Richard T., Andrulis, Irene L., Anton-Culver, Hoda, Barrdahl, Myrto, Baynes, Caroline, Beckmann, Matthias W., Benitez, Javier, Brauch, Hiltrud, Brinton, Louise, Broberg, Per, Brucker, Sara Y., Burwinkel, Barbara, Caldés, Trinidad, Canzian, Federico, Christiansen, Hans, Collée, Margriet, Cornelissen, Sten, Couch, Fergus J., Cox, David, Cross, Simon S., Cunningham, Julie M., Dörk, Thilo, dos-Santos-Silva, Isabel, Eccles, Diana M., Engel, Christoph, Eriksson, Mikael, Fachal, Laura, Figueroa, Jonine, Flesch-Janys, Dieter, Fletcher, Olivia, Gabrielson, Marike, Gaudet, Mia M., Giles, Graham G., Goldberg, Mark S., González-Neira, Anna, Guénel, Pascal, Håkansson, Niclas, Hall, Per, Hamann, Ute, Harrington, Patricia, Hein, Alexander, Hicks, Belynda, Hoover, Robert N., Huang, Guanmengqian, Humphreys, Keith, Hunter, David J., Jakubowska, Anna, John, Esther M., Jones, Kristine, Jones, Michael E., Jung, Audrey, Khusnutdinova, Elza, Kristensen, Vessela N., Lambrechts, Diether, Le Marchand, Loic, Li, Jingmei, Lo, Wing-Yee, Loibl, Sibylle, Lubinski, Jan, Luccarini, Craig, Lux, Michael P., Meindl, Alfons, Nevanlinna, Heli, Olopade, Olufunmilayo I., Peterlongo, Paolo, Peto, Julian, Presneau, Nadege, Rennert, Gad, Romero, Atocha, Romm, Jane, Rudolph, Anja, Saloustros, Emmanouil, Sandler, Dale P., Schmidt, Marjanka K., Scott, Rodney J., Scott, Christopher G., Seal, Sheila, Surowy, Harald, Tamimi, Rulla M., Tapper, William, Tessier, Daniel C., Tollenaar, Rob A. E. M., Torres, Diana, Truong, Thérèse, Van Den Berg, David, Vincent, Daniel, Whittemore, Alice S., Wildiers, Hans, Willett, Walter C., Wolk, Alicja, Ziogas, Argyrios, Dunning, Alison M., Simard, Jacques, Easton, Douglas F., Zheng, Wei

    Published in Nature genetics (01-07-2018)
    “…The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes…”
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    Genome-wide association analysis identifies three new breast cancer susceptibility loci by Fletcher, Olivia, Turnbull, Clare, Dicks, Ed, Dennis, Joe, Luccarini, Craig, Baynes, Caroline, Driver, Kristy, Orr, Nicholas, dos Santos Silva, Isabel, Uitterlinden, Andre G, Rivadeneira, Fernando, Hall, Per, Czene, Kamila, Aittomäki, Kristiina, Meindl, Alfons, Lichtner, Peter, Nickels, Stefan, Flesch-Janys, Dieter, Tsimiklis, Helen, Schmidt, Daniel, Bui, Minh, Apicella, Carmel, Park, Daniel J, Chanock, Stephen J, Verhoef, Senno, Hogervorst, Frans B L, Fasching, Peter A, Beckmann, Matthias W, Ekici, Arif B, Tomlinson, Ian, Kerin, Michael, Sohn, Christof, Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Menegaux, Florence, Nordestgaard, Børge G, Flyger, Henrik, Milne, Roger L, Alonso, M Rosario, Benítez, Javier, Anton-Culver, Hoda, Ziogas, Argyrios, Brenner, Hermann, Stegmaier, Christa, Brauch, Hiltrud, Brüning, Thomas, Eilber, Ursula, Bremer, Michael, Hillemanns, Peter, Antonenkova, Natalia N, Rogov, Yuri I, Karstens, Johann H, Bermisheva, Marina, Khusnutdinova, Elza, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Hartikainen, Jaana M, Floris, Giuseppe, Fortuzzi, Stefano, Peterlongo, Paolo, Couch, Fergus J, Stevens, Kristen, Giles, Graham G, Baglietto, Laura, Severi, Gianluca, Alnæs, Grethe Grenaker, Kristensen, Vessela, Børrensen-Dale, Anne-Lise, John, Esther M, Miron, Alexander, Andrulis, Irene L, Devilee, Peter, Seynaeve, Caroline, Figueroa, Jonine D, Garcia-Closas, Montserrat, Brinton, Louise, Hooning, Maartje J, van den Ouweland, Ans M W, Reed, Malcolm W R, Shah, Mitul, Jakubowska, Ania, Lubinski, Jan, Durda, Katarzyna, Jones, Michael, Schoemaker, Minouk, Swerdlow, Anthony, Beesley, Jonathan, Chen, Xiaoqing, Lophatananon, Artitaya, Rattanamongkongul, Suthee, Noh, Dong-Young, Velentzis, Louiza, Tapper, Will J, Gerty, Susan M, Graham, Nikki J, Ponder, Bruce A J, Dunning, Alison M, Peto, Julian

    Published in Nature genetics (01-03-2012)
    “…Douglas Easton and colleagues report a genome-wide association analyses for breast cancer in ~70,000 cases and ~68,000 controls. They identify three new breast…”
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    Genome-wide association study of germline variants and breast cancer-specific mortality by Canisius, Sander, Beesley, Jonathan, Lecarpentier, Julie, Anton-Culver, Hoda, Bermisheva, Marina, Bernstein, Leslie, Blomqvist, Carl, Bonanni, Bernardo, Børresen-Dale, Anne-Lise, Brucker, Sara Y., Burwinkel, Barbara, Campa, Daniele, Carter, Brian D., Chang-Claude, Jenny, Chenevix-Trench, Georgia, Cheng, Ting-Yuan David, Clarke, Christine L., Cordina-Duverger, Emilie, Couch, Fergus J., Dunn, Janet A., Dunning, Alison M., Durcan, Lorraine, Eliassen, A. Heather, Ellberg, Carolina, Eriksson, Mikael, Gabrielson, Marike, Galle, Eva, Gapstur, Susan M., García-Closas, Montserrat, García-Sáenz, José A., Gaudet, Mia M., Giles, Graham G., Goldgar, David E., Guénel, Pascal, Haeberle, Lothar, Hahnen, Eric, Haiman, Christopher A., Hankinson, Susan, Hart, Steven N., Hillemanns, Peter, Holleczek, Bernd, Hooning, Maartje J., Hopper, John L., Huang, Guanmengqian, Humphreys, Keith, Hunter, David J., John, Esther M., Jones, Michael E., Kabisch, Maria, Kaczmarek, Katarzyna, Kiiski, Johanna I., Knight, Julia A., Ko, Yon-Dschun, Kosma, Veli-Matti, Kristensen, Vessela N., Lee, Eunjung, Li, Lian, Lindblom, Annika, Lindström, Sara, Lo, Wing-Yee, Lux, Michael P., MacInnis, Robert J., Makalic, Enes, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Martinez, Maria Elena, Mavroudis, Dimitrios, Meindl, Alfons, Middha, Pooja, Mulligan, Anna Marie, Nassir, Rami, Nielsen, Sune F., Orr, Nick, Pankratz, V. Shane, Perez, Jose I. A., Pinchev, Mila, Pylkäs, Katri, Rack, Brigitte, Rennert, Hedy S., Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Schumacher, Fredrick, Shah, Mitul, Simard, Jacques, Smeets, Ann, Tamimi, Rulla M., Teixeira, Manuel R., Turnbull, Clare, van Asperen, Christi J., van den Ouweland, Ans M. W., Whittemore, Alice S., Yang, Xiaohong R., Zhang, Yan, Easton, Douglas F., Fasching, Peter A., Pharoah, Paul D. P., Schmidt, Marjanka K.

    Published in British journal of cancer (2019)
    “…Background We examined the associations between germline variants and breast cancer mortality using a large meta-analysis of women of European ancestry…”
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    Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer by Purrington, Kristen S., Eccles, Diana, Yannoukakos, Drakoulis, Fasching, Peter A., Miron, Penelope, Carpenter, Jane, Chang-Claude, Jenny, Martin, Nicholas G., Montgomery, Grant W., Kristensen, Vessela, Anton-Culver, Hoda, Goodfellow, Paul, Tapper, William J., Rafiq, Sajjad, Gerty, Susan M., Durcan, Lorraine, Konstantopoulou, Irene, Fostira, Florentia, Vratimos, Athanassios, Konstanta, Irene, Kotoula, Vassiliki, Lakis, Sotiris, Dimopoulos, Meletios A., Skarlos, Dimosthenis, Pectasides, Dimitrios, Fountzilas, George, Beckmann, Matthias W., Hein, Alexander, Ruebner, Matthias, Ekici, Arif B., Hartmann, Arndt, Schulz-Wendtland, Ruediger, Renner, Stefan P., Janni, Wolfgang, Rack, Brigitte, Scholz, Christoph, Neugebauer, Julia, Andergassen, Ulrich, Lux, Michael P., Haeberle, Lothar, Clarke, Christine, Pathmanathan, Nirmala, Rudolph, Anja, Flesch-Janys, Dieter, Nickels, Stefan, Olson, Janet E., Ingle, James N., Olswold, Curtis, Slettedahl, Seth, Eckel-Passow, Jeanette E., Anderson, S.Keith, Visscher, Daniel W., Cafourek, Victoria L., Sicotte, Hugues, Prodduturi, Naresh, Weiderpass, Elisabete, Bernstein, Leslie, Ziogas, Argyrios, Giles, Graham G., Baglietto, Laura, Kosma, Veli-Matti, Fischer, Hans-Peter, Reed, Malcom W.R., Cross, Simon S., Deming-Halverson, Sandra, Shrubsole, Martha, Cai, Qiuyin, Shu, Xiao-Ou, Daly, Mary, Weaver, JoEllen, Ross, Eric, Klemp, Jennifer, Sharma, Priyanka, Rüdiger, Thomas, Ulmer, Hans-Ulrich, Försti, Asta, Khoury, Thaer, Kumar, Shicha, Pilarski, Robert, Shapiro, Charles L., Greco, Dario, Heikkilä, Päivi, Aittomäki, Kristiina, Blomqvist, Carl, Irwanto, Astrid, Liu, Jianjun, Pankratz, Vernon Shane, Wang, Xianshu, Severi, Gianluca, Easton, Douglas, Hall, Per, Brauch, Hiltrud, Cox, Angela, Godwin, Andrew K., Hamann, Ute, Ambrosone, Christine, Toland, Amanda Ewart, Nevanlinna, Heli, Vachon, Celine M., Couch, Fergus J.

    Published in Carcinogenesis (New York) (01-05-2014)
    “…Summary In a genome-wide scan, we show that 30 variants in 25 genomic regions are associated with risk of TN breast cancer. Women carrying many of the risk…”
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    Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1 by Michailidou, Kyriaki, Edwards, Stacey L., Prathalingham, Radhika, Dennis, Joe, de Santiago, Ines, Hopper, John L., Van ’t Veer, Laura J., Hogervorst, Frans B., Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Lux, Michael P., Peto, Julian, dos Santos Silva, Isabel, Johnson, Nichola, Miller, Nicola, Marme, Federick, Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Menegaux, Florence, Bojesen, Stig E., Nordestgaard, Børge G., Flyger, Henrik, Zamora, M. Pilar, Benitez, Javier, Ziogas, Argyrios, Brenner, Hermann, Müller, Heiko, Arndt, Volker, Schmutzler, Rita K., Engel, Christoph, Brauch, Hiltrud, Brüning, Thomas, Ko, Yon-Dschun, Muranen, Taru A., Blomqvist, Carl, Matsuo, Keitaro, Dörk, Thilo, Helbig, Sonja, Bogdanova, Natalia V., Lindblom, Annika, Mannermaa, Arto, Wu, Anna H., Stram, Daniel O., Thienpont, Bernard, Christiaens, Marie-Rose, Flesch-Janys, Dieter, Radice, Paolo, Peterlongo, Paolo, Bernard, Loris, Wang, Xianshu, Purrington, Kristen, Severi, Gianluca, Baglietto, Laura, McLean, Catriona, Henderson, Brian E., Simard, Jacques, Goldberg, Mark S., Labrèche, France, Yip, Cheng-Har, Phuah, Sze-Yee, Grenaker Alnæs, Grethe, Børresen-Dale, Anne-Lise, Pylkäs, Katri, Kauppila, Saila, Knight, Julia A., Devilee, Peter, Seynaeve, Caroline M., García-Closas, Montserrat, Figueroa, Jonine, Czene, Kamila, Darabi, Hartef, Hooning, Maartje J., Martens, John W.M., van den Ouweland, Ans M.W., Li, Jingmei, Shu, Xiao-Ou, Lu, Wei, Gao, Yu-Tang, Cai, Hui, Reed, Malcolm W.R., Signorello, Lisa B., Pharoah, Paul D.P., Ghoussaini, Maya, Choi, Ji-Yeob, Noh, Dong-Young, Hui, Miao, Ulmer, Hans-Ulrich, Jakubowska, Anna, Lubinski, Jan, Durda, Katarzyna, McKay, James, Slager, Susan, Shen, Chen-Yang, Hou, Ming-Feng, Swerdlow, Anthony, Ashworth, Alan, Schoemaker, Minouk J., Dunning, Alison M.

    Published in American journal of human genetics (05-12-2013)
    “…The 10q26 locus in the second intron of FGFR2 is the locus most strongly associated with estrogen-receptor-positive breast cancer in genome-wide association…”
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    The Impasse on Overall Survival in Oncology Reimbursement Decision-Making: How Can We Resolve This? by Lux, Michael Patrick, Ciani, Oriana, Dunlop, William C N, Ferris, Andrea, Friedlander, Michael

    Published in Cancer management and research (01-01-2021)
    “…Mature overall survival (OS) data are often unavailable at the time of regulatory and reimbursement decisions for a new cancer treatment. For patients with…”
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    Abstract P2-09-04: Identification of a neoantigen targeted by tumor-infiltrating lymphocytes in a patient with Her2+ breast cancer by Reimann, H, Nguyen, A, Hübner, H, Erber, R, Bausenwein, J, Van der Meijden, ED, Lux, MP, Jud, S, Griffioen, M, Rauh, C, Sanborn, JZ, Benz, SC, Rabizadeh, S, Beckmann, MW, Mackensen, A, Rübner, M, Fasching, PA, Kremer, AN

    Published in Cancer research (Chicago, Ill.) (15-02-2019)
    “…Abstract Background: Recent studies have demonstrated that the number of tumor infiltrating lymphocytes (TILs) positively correlates with outcome and response…”
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    Hereditary breast and ovarian cancer : review and future perspectives by LUX, Michael P, FASCHING, Peter A, BECKMANN, Matthias W

    “…Breast cancer (BC) is the most frequent carcinoma in women. The cumulative risk for the disease is 10% up to the age of 80 years. A familial history of BC and…”
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    Abstract OT3-02-09: Seraphina – Safety efficacy and patient reported outcomes of advanced breast cancer patients: Therapy management with NAB-paclitaxel in daily routine by Fasching, PA, Wallwiener, M, Lux, MP, Mueller, V, Schneeweiss, A, Tesch, H, Brucker, SY, Haeberle, L, Spall, T, Belleville, E, Lück, H-J

    Published in Cancer research (Chicago, Ill.) (15-02-2016)
    “…Abstract BACKGROUND Treatment of patients with advanced breast cancer (ABC) has evolved significantly. Nevertheless, further improvement in ABC treatment is a…”
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