Search Results - "Luukkonen, M"

DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras by Zhang, Xiaoyu, Luukkonen, Lena M, Eissler, Christie L, Crowley, Vincent M, Yamashita, Yu, Schafroth, Michael A, Kikuchi, Shota, Weinstein, David S, Symons, Kent T, Nordin, Brian E, Rodriguez, Joe L, Wucherpfennig, Thomas G, Bauer, Ludwig G, Dix, Melissa M, Stamos, Dean, Kinsella, Todd M, Simon, Gabriel M, Baltgalvis, Kristen A, Cravatt, Benjamin F

“…Ligand-induced protein degradation has emerged as a compelling approach to promote the targeted elimination of proteins from cells by directing these proteins…”
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Footprint Evaluation for Flux and Concentration Measurements for an Urban-Like Canopy with Coupled Lagrangian Stochastic and Large-Eddy Simulation Models by Hellsten, Antti, Luukkonen, Sofia-M., Steinfeld, Gerald, Kanani-Sühring, Farah, Markkanen, Tiina, Järvi, Leena, Lento, Juha, Vesala, Timo, Raasch, Siegfried

“…A footprint algorithm, based on a Lagrangian stochastic (LS) model embedded into a parallelized large-eddy simulation (LES) model, is used for the evaluation…”
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Disc herniation-related back pain impairs feed-forward control of paraspinal muscles by Leinonen, V, Kankaanpää, M, Luukkonen, M, Hänninen, O, Airaksinen, O, Taimela, S

“…A comparative study of lumbar paraspinal muscle reflexes during sudden upper limb loading in healthy control subjects and patients with sciatica. To assess…”
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Lumbar spinal stenosis: a matched-pair study of operated and non-operated patients by Herno, A, Airaksinen, O, Saari, T, Luukkonen, M

“…The prevailing opinion seems to accept that the natural course of lumbar spinal stenosis is one of progressive worsening, and that only surgery can check this…”
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A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm by Luukkonen, Tiia M, Pöyhönen, Minna, Palotie, Aarno, Ellonen, Pekka, Lagström, Sonja, Lee, Joseph H, Terwilliger, Joseph D, Salonen, Riitta, Varilo, Teppo

“…Balanced chromosomal rearrangements occasionally have strong phenotypic effects, which may be useful in understanding pathobiology. However, conventional…”
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One-year outcome in early aneurysm surgery : a 14 years experience by HERNESNIEMI, J, VAPALAHTI, M, NISKANEN, M, TAPANINAHO, A, KARI, A, LUUKKONEN, M, PURANEN, M, SAARI, T, RAJPAR, M

“…In a consecutive series of 1150 patients with cerebral aneurysms diagnosed in our department by angiography or autopsy between the years 1977-1990, 1007…”
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Shunt-dependent hydrocephalus after subarachnoid haemorrhage and aneurysm surgery : timing of surgery is not a risk factor by TAPANINAHO, A, HERNESNIEMI, J, VAPALAHTI, M, NISKANEN, M, KARI, A, LUUKKONEN, M, PURANEN, M

“…Early hydrocephalus is a risk factor of shunt-dependent late hydrocephalus (SDHC). In the CT era 1980-1990 we had 835 consecutive patients operated on because…”
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Lumbar disc herniations in children: a long-term clinical and magnetic resonance imaging follow-up study by Luukkonen, K. Partanen, M. Vapalahti, M.

“…Abstract To determine the long-term outcome of 12 youthful patients with lumbar disc herniation, who, at the time of surgery, were 15 years old or younger…”
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Evaluation of a hand-held blood gas analyzer for rapid determination of blood gases, electrolytes and metabolites in intensive care setting by Luukkonen, Antti A M, Lehto, Tiina M, Hedberg, Pirjo S M, Vaskivuo, Tommy E

“…Intensive care units, operating rooms, emergency departments, and neonatology units need rapid measurements of blood gases, electrolytes, and metabolites…”
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The effect of prior back surgery on surgical outcome in patients operated on for lumbar spinal stenosis. A matched-pair study by Herno, A, Airaksinen, O, Saari, T, Sihvonen, T, Luukkonen, M

“…It has been widely observed that the outcome after repeat lumbar surgery is rarely comparable to that of primary surgery. In particular, the results of repeat…”
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Comparative immunohistochemical study of group II (synovial-type) and group IV (cytosolic) phospholipases A2 in disc prolapse tissue by Habtemariam, A, Grönblad, M, Virri, J, Airaksinen, O, Luukkonen, M, Turunen, V, Savolainen, S, Karaharju, E

“…Phospholipase A2 (PLA2) has been suggested to be present in herniated disc tissue and it could possibly be involved in sciatica/ discogenic back pain…”
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Microvascular myocutaneous flaps in the lumbosacral area using the iliac artery and vein as recipient vessels by Mustonen, Paula Katriina, Härmä, Markku Antero, Berg, Marja Helena, Luukkonen, Matti Tapani

“…Lumbosacral tissue defects are usually closed with local flaps. Sometimes in large high-situated defects free microvascular flaps are used. However, finding a…”
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Inhibitory activity of the equine infectious anemia virus major 5' splice site in the absence of Rev by Tan, W. (Karolinska Institute, Stockholm, Sweden.), Schalling, M, Zhao, C, Luukkonen, M, Nilsson, M, Fenyo, E.M, Pavlakis, G.N, Schwartz, S

“…The major 5' splice site of equine infectious anemia virus (EIAV) conforms to the consensus 5' splice site in eight consecutive positions and is located…”
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Unruptured Intracranial Aneurysms — Risk of Rupture and Risks of Surgical Intervention by Wiebers, D, Whisnant, J, bes, G, Meissner, I

“…Intracranial aneurysms are common. 1 – 6 Autopsy studies have shown that the overall frequency in the general population ranges from 0.2 to 9.9 percent (mean…”
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Lumbar Paraspinal Muscle Function, Perception of Lumbar Position, and Postural Control in Disc Herniation-Related Back Pain by LEINONEN, Ville, KANKAANPÄÄ, Markku, LUUKKONEN, Matti, KANSANEN, Martti, HÄNNINEN, Osmo, AIRAKSINEN, Olavi, TAIMELA, Simo

“…A follow-up study evaluating postural control, lumbar movement perception, and paraspinal muscle reflexes in disc herniation-related chronic low back pain…”
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A conditional U5 snRNA mutation affecting pre-mRNA splicing and nuclear pre-mRNA retention identifies SSD1/SRK1 as a general splicing mutant suppressor by Luukkonen, B.G. Mattias, Séraphin, Bertrand

“…A combination of point mutations disrupting both stem 1 and stem 2 of U5 snRNA (U5AI) was found to confer a thermosensitive phenotype in vivo. In a strain…”
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Hyaluronan Enters Keratinocytes by a Novel Endocytic Route for Catabolism by Tammi, Raija, Rilla, Kirsi, Pienimäki, Juha-Pekka, MacCallum, Donald K., Hogg, Michael, Luukkonen, Merja, Hascall, Vincent C., Tammi, Markku

“…Hyaluronan synthesized in the epidermis has an exceptionally short half-life, indicative of its catabolism by epidermal keratinocytes. An intracellular pool of…”
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Fulfilling a wish by Eizenga, P, Luukkonen, M E

“…As awareness of the need for organ donations grows, so does the frequency of requests by terminal patients to become donors. Recently, we experienced just such…”
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Impaired utilization of exogenous amino acids after surgery for subarachnoid haemorrhage by Hersio, K, Vapalahti, M, Kari, A, Takala, J, Hernesniemi, J, Tapaninaho, A, Luukkonen, M

“…We studied the metabolic response to acute aneurysm surgery and its modification by parenteral nutrition. Forty-eight patients receiving perioperative…”
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Changed lamellipodial extension, adhesion plaques and migration in epidermal keratinocytes containing constitutively expressed sense and antisense hyaluronan synthase 2 (Has2) genes by Rilla, Kirsi, Lammi, Mikko J, Sironen, Reijo, Törrönen, Kari, Luukkonen, Merja, Hascall, Vincent C, Midura, Ronald J, Hyttinen, Mika, Pelkonen, Jukka, Tammi, Markku, Tammi, Raija

“…Hyaluronan is a major component of the epidermal extracellular matrix, is actively synthesized by keratinocytes and shows fast matrix turnover in the…”
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