Search Results - "Luu‐The, Van"

The intracrine sex steroid biosynthesis pathways by Luu-The, Van, Labrie, Fernand

“…There is an increasing number of differences reported between the steroidogenesis pathways described in the traditional literature related to gonadal…”
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Assessment of steroidogenesis and steroidogenic enzyme functions by Luu-The, Van

“…•Clarification of steroidogenesis in endocrine glands and steroidogenesis in peripheral intracrine tissues.•Pathways of dihydrotestosterone and estradiol…”
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Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue by Veilleux, Alain, Laberge, Philippe Y., Morency, Jacques, Noël, Suzanne, Luu-The, Van, Tchernof, André

“…Adipose tissue glucocorticoid action relies on local enzymatic interconversion and glucocorticoid receptor (GR) availability. 11β-Hydroxysteroid dehydrogenase…”
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Effects of androgens on adipocyte differentiation and adipose tissue explant metabolism in men and women by Blouin, Karine, Nadeau, Mélanie, Perreault, Martin, Veilleux, Alain, Drolet, Renée, Marceau, Picard, Mailloux, Jacques, Luu-The, Van, Tchernof, André

“…Summary Objective  To examine the effects of aromatizable or nonaromatizable androgens on abdominal subcutaneous (SC) and omental (OM) adipose tissue lipid…”
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Steroid biosynthesis within the frog brain: a model of neuroendocrine regulation by Do Rego, Jean-Luc, Seong, Jae Young, Burel, Delphine, Luu-The, Van, Larhammar, Dan, Tsutsui, Kazuyoshi, Pelletier, Georges, Tonon, Marie-Christine, Vaudry, Hubert

“…There is now clear evidence that the brain, similar to the adrenal gland, gonads, and placenta, is a steroidogenic organ. Notably in the frog brain, the…”
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Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides by Do Rego, Jean Luc, Seong, Jae Young, Burel, Delphine, Leprince, Jerôme, Luu-The, Van, Tsutsui, Kazuyoshi, Tonon, Marie-Christine, Pelletier, Georges, Vaudry, Hubert

“…Abstract Neuroactive steroids synthesized in neuronal tissue, referred to as neurosteroids, are implicated in proliferation, differentiation, activity and…”
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Characterization of Type 12 17β-Hydroxysteroid Dehydrogenase, an Isoform of Type 3 17β-Hydroxysteroid Dehydrogenase Responsible for Estradiol Formation in Women by Luu-The, Van, Tremblay, Philippe, Labrie, Fernand

“…A novel 17β-hydroxysteroid dehydrogenase (17β-HSD) chronologically named type 12 17β-HSD (17β-HSD12), that transforms estrone (E1) into estradiol (E2) was…”
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Updated survey of the steroid-converting enzymes in human adipose tissues by Tchernof, André, Mansour, Mohamed Fouad, Pelletier, Mélissa, Boulet, Marie-Michèle, Nadeau, Mélanie, Luu-The, Van

“…•We provide a survey of the many steroid-converting enzymes found in adipose tissues.•Their activities and potential roles are also reviewed.•Some enzymes may…”
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Androgen biosynthetic pathways in the human prostate by Luu-The, Van, PhD, Bélanger, Alain, PhD, Labrie, Fernand, MD, PhD

“…It is well recognized that there are two androgens, namely testosterone (T) and dihydrotestosterone (DHT); T plays an important role in the testis and muscle,…”
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Improved real-time RT-PCR method for high-throughput measurements using second derivative calculation and double correction by Luu-The, Van, Paquet, Nathalie, Calvo, Ezequiel, Cumps, Jean

“…Quantification of mRNA expression levels using real-time reverse transcription PCR (RT-PCR) is increasingly used to validate results of DNA microarrays or…”
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Analysis and characteristics of multiple types of human 17β-hydroxysteroid dehydrogenase by Luu-The, Van

“…Androgens and estrogens are not only synthesized in the gonads but also in peripheral target tissues. Accordingly, recent molecular cloning has allowed us to…”
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Steroid Biosynthesis within the Frog Brain by Rego, Jean-Luc Do, Seong, Jae Young, Burel, Delphine, Luu-The, Van, Larhammar, Dan, Tsutsui, Kazuyoshi, Pelletier, Georges, Tonon, Marie-Christine, Vaudry, Hubert

“…There is now clear evidence that the brain, similar to the adrenal gland, gonads, and placenta, is a steroidogenic organ. Notably in the frog brain, the…”
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Endocrine and Intracrine Sources of Androgens in Women: Inhibition of Breast Cancer and Other Roles of Androgens and Their Precursor Dehydroepiandrosterone by Labrie, Fernand, Luu-The, Van, Labrie, Claude, Bélanger, Alain, Simard, Jacques, Lin, Sheng-Xiang, Pelletier, Georges

“…Serum androgens as well as their precursors and metabolites decrease from the age of 30–40 yr in women, thus suggesting that a more physiological hormone…”
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Pathways of adipose tissue androgen metabolism in women: depot differences and modulation by adipogenesis by Blouin, Karine, Nadeau, Mélanie, Mailloux, Jacques, Daris, Marleen, Lebel, Stephane, Luu-The, Van, Tchernof, André

“…The objective was to examine pathways of androgen metabolism in abdominal adipose tissue in women. Abdominal subcutaneous (SC) and omental (OM) adipose tissue…”
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Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin™ and full thickness model from Episkin by Luu-The, Van, Duche, Daniel, Ferraris, Corinne, Meunier, Jean-Roch, Leclaire, Jacques, Labrie, Fernand

“…Episkin™ and full thickness model from Episkin™ (FTM) are human skin models obtained from in vitro growth of keratinocytes into the five typical layers of the…”
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Glucocorticoid-induced androgen inactivation by aldo-keto reductase 1C2 promotes adipogenesis in human preadipocytes by Veilleux, Alain, Côté, Julie-Anne, Blouin, Karine, Nadeau, Mélanie, Pelletier, Mélissa, Marceau, Picard, Laberge, Philippe Y, Luu-The, Van, Tchernof, André

“…Adipogenesis and lipid storage in human adipose tissue are inhibited by androgens such as DHT. Inactivation of DHT to 3α-diol is stimulated by glucocorticoids…”
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Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland by Calvo, Ezequiel, Luu-The, Van, Belleau, Pascal, Martel, Céline, Labrie, Fernand

“…Novel agents for the endocrine therapy of breast cancer are needed, especially in order to take advantage of the multiple consecutive responses observed in…”
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Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line by Samson, Mélanie, Labrie, Fernand, Luu-The, Van

“…Estradiol (E2) plays a crucial role in all reproduction processes. In the placenta, it is well recognized that E2 is synthesized from fetal…”
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Differential androgen and estrogen substrates specificity in the mouse and primates type 12 17β-hydroxysteroid dehydrogenase by Blanchard, Pierre-Gilles, Luu-The, Van

“…Recently, we have shown that human and monkey type 12 17β-hydroxysteroid dehydrogenases (17β-HSD12) are estrogen-specific enzymes catalyzing the transformation…”
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The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central‐type benzodiazepine receptors by Do‐Rego, Jean‐Luc, Mensah‐Nyagan, Ayikoe Guy, Beaujean, Delphine, Leprince, Jérôme, Tonon, Marie‐Christine, Luu‐The, Van, Pelletier, Georges, Vaudry, Hubert

“…Neurosteroids may play a major role in the regulation of various neurophysiological and behavioural processes. However, while the biochemical pathways involved…”
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