Search Results - "Lutz, Stefan Z."

Insulin receptor isoforms A and B as well as insulin receptor substrates-1 and -2 are differentially expressed in prostate cancer by Heni, Martin, Hennenlotter, Jörg, Scharpf, Marcus, Lutz, Stefan Z, Schwentner, Christian, Todenhöfer, Tilman, Schilling, David, Kühs, Ursula, Gerber, Valentina, Machicao, Fausto, Staiger, Harald, Häring, Hans-Ulrich, Stenzl, Arnulf

“…In different cancers types, insulin receptor isoform composition or insulin receptor substrate (IRS) isoforms are different to healthy tissue. This may be a…”
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Inceptor correlates with markers of prostate cancer progression and modulates insulin/IGF1 signaling and cancer cell migration by Wissmiller, Katharina, Bilekova, Sara, Franko, Andras, Lutz, Stefan Z., Katsburg, Miriam, Gulde, Sebastian, Pellegata, Natalia S., Stenzl, Arnulf, Heni, Martin, Berti, Lucia, Häring, Hans-Ulrich, Lickert, Heiko

“…The insulin/insulin-like growth factor 1 (IGF1) pathway is emerging as a crucial component of prostate cancer progression. Therefore, we investigated the role…”
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Common genetic variation in the human CTF1 locus, encoding cardiotrophin-1, determines insulin sensitivity by Lutz, Stefan Z, Franck, Olga, Böhm, Anja, Machann, Jürgen, Schick, Fritz, Machicao, Fausto, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald

“…Recently, cardiotrophin-1, a member of the interleukin-6 family of cytokines was described to protect beta-cells from apoptosis, to improve glucose-stimulated…”
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Sex-Specific Associations of Testosterone With Metabolic Traits by Lutz, Stefan Z, Wagner, Robert, Fritsche, Louise, Peter, Andreas, Rettig, Ingo, Willmann, Caroline, Fehlert, Ellen, Martus, Peter, Todenhöfer, Tilman, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich, Heni, Martin

“…Testosterone levels are differentially linked with diabetes risk in men and women: lower testosterone levels in men and higher testosterone levels in women are…”
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Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein by Welte, Stefan A., Sinzger, Christian, Lutz, Stefan Z., Singh‐Jasuja, Harpreet, Sampaio, Kerstin Laib, Eknigk, Ute, Rammensee, Hans‐Georg, Steinle, Alexander

“…Human cytomegalovirus (HCMV) has evolved a multitude of molecular mechanisms to evade the antiviral immune defense of the host. Recently, using soluble…”
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Overexpression of Kinase-Negative Protein Kinase Cδ in Pancreatic β-Cells Protects Mice From Diet-Induced Glucose Intolerance and β-Cell Dysfunction by HENNIGE, Anita M, RANTA, Felicia, HÄRING, Hans-Ulrich, ULLRICH, Susanne, HEINZELMANN, Isabel, DÜFER, Martina, MICHAEL, Diana, BRAUMÜLLER, Heidi, LUTZ, Stefan Z, LAMMERS, Reiner, DREWS, Gisela, BOSCH, Fatima

“…Overexpression of Kinase-Negative Protein Kinase Cδ in Pancreatic β-Cells Protects Mice From Diet-Induced Glucose Intolerance and β-Cell Dysfunction Anita M…”
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Toll‐like receptors 2 and 4 impair insulin‐mediated brain activity by interleukin‐6 and osteopontin and alter sleep architecture by Sartorius, Tina, Lutz, Stefan Z., Hoene, Miriam, Waak, Jens, Peter, Andreas, Weigert, Cora, Rammensee, Hans‐Georg, Kahle, Philipp J., Häring, Hans‐Ulrich, Hennige, Anita M.

“…Impaired insulin action in the brain represents an early step in the progression toward type 2 diabetes, and elevated levels of saturated free fatty acids are…”
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Genetic Ablation of cGMP-Dependent Protein Kinase Type I Causes Liver Inflammation and Fasting Hyperglycemia by LUTZ, Stefan Z, HENNIGE, Anita M, HÄRING, Hans-Ulrich, FEIL, Robert, FEIL, Susanne, PETER, Andreas, GERLING, Andrea, MACHANN, Jürgen, KRÖBER, Stefan M, RATH, Michaela, SCHÜRMANN, Annette, WEIGERT, Cora

“…The nitric oxide/cGMP/cGMP-dependent protein kinase type I (cGKI) signaling pathway regulates cell functions that play a pivotal role in the pathogenesis of…”
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Increased Expressions of Matrix Metalloproteinases (MMPs) in Prostate Cancer Tissues of Men with Type 2 Diabetes by Franko, Andras, Berti, Lucia, Hennenlotter, Jörg, Rausch, Steffen, Scharpf, Marcus O., de Angelis, Martin Hrabĕ de, Stenzl, Arnulf, Peter, Andreas, Birkenfeld, Andreas L., Lutz, Stefan Z., Häring, Hans-Ulrich, Heni, Martin

“…Type 2 diabetes (T2D) is associated with worse prognosis of prostate cancer (PCa). The molecular mechanisms behind this association are still not fully…”
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Sunitinib specifically augments glucose-induced insulin secretion by Lutz, Stefan Z., Ullrich, Axel, Häring, Hans-Ulrich, Ullrich, Susanne, Gerst, Felicia

“…The tyrosine kinase inhibitor sunitinib is used for the treatment of numerous cancers in humans. In diabetic patients, sunitinib lowers blood glucose levels…”
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Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity by Lutz, Stefan Z, Peter, Andreas, Machicao, Fausto, Lamprinou, Apostolia, Machann, Jürgen, Schick, Fritz, Königsrainer, Ingmar, Königsrainer, Alfred, Fritsche, Andreas, Staiger, Harald, Häring, Hans-Ulrich, Stefan, Norbert, Kantartzis, Konstantinos

“…Context/Objective: Acute pharmacological inhibition of 11β-hydroxysteroid-dehydrogenase 1 (11β-HSD1), which converts cortisone into the much more potent…”
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Telemedicine in mobile geriatric rehabilitation : Results of the VITAAL study by Burdinski, Sandra, Smeaton, Susan, Lutz, Stefan Z, Partheymüller, Anja, Geyik, Ugur, Eschweiler, Gerhard W, Metzger, Florian G

“…In order to implement the principle of rehabilitation before care, adaptive concepts for geriatric patients are required. Patients with visual impairments,…”
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Human Prostate Cancer is Characterized by an Increase in Urea Cycle Metabolites by Franko, Andras, Shao, Yaping, Heni, Martin, Hennenlotter, Jörg, Hoene, Miriam, Hu, Chunxiu, Liu, Xinyu, Zhao, Xinjie, Wang, Qingqing, Birkenfeld, Andreas L, Todenhöfer, Tilman, Stenzl, Arnulf, Peter, Andreas, Häring, Hans-Ulrich, Lehmann, Rainer, Xu, Guowang, Lutz, Stefan Z

“…Despite it being the most common incident of cancer among men, the pathophysiological mechanisms contributing to prostate cancer (PCa) are still poorly…”
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cGMP-dependent protein kinase I (cGKI) modulates human hepatic stellate cell activation by Franko, Andras, Kovarova, Marketa, Feil, Susanne, Feil, Robert, Wagner, Robert, Heni, Martin, Königsrainer, Alfred, Ruoß, Marc, Nüssler, Andreas K., Weigert, Cora, Häring, Hans-Ulrich, Lutz, Stefan Z., Peter, Andreas

“…The activation of hepatic stellate cells (HSCs) plays a crucial role in liver fibrosis, however the role of HSCs is less understood in hepatic insulin…”
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The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet by Lutz, Stefan Z, Hennige, Anita M, Peter, Andreas, Kovarova, Marketa, Totsikas, Charisis, Machann, Jürgen, Kröber, Stefan M, Sperl, Bianca, Schleicher, Erwin, Schick, Fritz, Heni, Martin, Ullrich, Axel, Häring, Hans-Ulrich, Stefan, Norbert

“…Abstract Context The effect of a lifestyle intervention to reduce liver fat content in nonalcoholic fatty liver disease in humans is influenced by genetics. We…”
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Antihyperglycaemic therapies and cancer risk by Lutz, Stefan Z, Staiger, Harald, Fritsche, Andreas, Häring, Hans-Ulrich

“…This review is aimed at highlighting the potential mitogenic/tumour growth-promoting or antimitogenic/tumour growth-inhibiting effects of the main…”
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Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans by Lutz, Stefan Z., Falcenberg, Mathias, Machicao, Fausto, Peter, Andreas, Kächele, Martin, Randrianarisoa, Elko, Lehn-Stefan, Angela, Wagner, Robert, Machann, Jürgen, Schick, Fritz, Heni, Martin, Ullrich, Axel, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald, Kantartzis, Konstantinos

“…Genetically modified mice models suggest an important role for G-protein-coupled receptor kinase 5 (GRK5) in the pathophysiology of obesity and related…”
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MICA/NKG2D-mediated immunogene therapy of experimental gliomas by FRIESE, Manuel A, PLATTEN, Michael, WELLER, Michael, LUTZ, Stefan Z, NAUMANN, Ulrike, AULWURM, Steffen, BISCHOF, Felix, BÜHRING, Hans-Jörg, DICHGANS, Johannes, RAMMENSEE, Hans-Georg, STEINLE, Alexander

“…The failure of conventional cancer therapy renders glioblastoma an attractive target for immunotherapy. Tumor cells expressing ligands of the activating…”
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Characterization of Hormone-Dependent Pathways in Six Human Prostate-Cancer Cell Lines: A Gene-Expression Study by Franko, Andras, Berti, Lucia, Guirguis, Alke, Hennenlotter, Jörg, Wagner, Robert, Scharpf, Marcus O, de Angelis, Martin Hrabĕ, Wißmiller, Katharina, Lickert, Heiko, Stenzl, Arnulf, Birkenfeld, Andreas L, Peter, Andreas, Häring, Hans-Ulrich, Lutz, Stefan Z, Heni, Martin

“…Prostate cancer (PCa), the most incident cancer in men, is tightly regulated by endocrine signals. A number of different PCa cell lines are commonly used for…”
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Transcript Levels of Aldo-Keto Reductase Family 1 Subfamily C (AKR1C) Are Increased in Prostate Tissue of Patients with Type 2 Diabetes by Franko, Andras, Berti, Lucia, Hennenlotter, Jörg, Rausch, Steffen, Scharpf, Marcus O., de Angelis, Martin Hrabĕ, Stenzl, Arnulf, Birkenfeld, Andreas L., Peter, Andreas, Lutz, Stefan Z., Häring, Hans-Ulrich, Heni, Martin

“…Aldo-keto reductase family 1 (AKR1) enzymes play a crucial role in diabetic complications. Since type 2 diabetes (T2D) is associated with cancer progression,…”
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