Search Results - "Luty, AJF"

Human genetic factors related to susceptibility to mild malaria in Gabon by Migot-Nabias, F, Mombo, L E, Luty, A J, Dubois, B, Nabias, R, Bisseye, C, Millet, P, Lu, C Y, Deloron, P

“…Several human genetic factors, including red blood cell polymorphisms (ABO blood group, sickle-cell trait, G6PD deficiency) as well as point mutations in the…”
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HLA alleles in relation to specific immunity to Liver Stage Antigen-1 from Plasmodium falciparum in Gabon by MIGOT-NABIAS, F, LUTY, A. J. F, MINH, T. N, FAJARDY, I, TAMOUZA, R, MARZAIS, F, CHARRON, D, DANZE, P.-M, RENAUT, A, DELORON, P

“…Cellular responses to synthetic peptides from the Liver Stage Antigen-1 (LSA-1) from Plasmodium falciparum were determined in 229 Gabonese children. HLA class…”
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Placental Malaria Increases Malaria Risk in the First 30 Months of Life by Schwarz, Norbert G., Adegnika, Ayola A., Breitling, Lutz P., Gabor, Julian, Agnandji, Selidji T., Newman, Robert D., Lell, Bertrand, Issifou, Saadou, Yazdanbakhsh, Maria, Luty, Adrian J. F., Kremsner, Peter G., Grobusch, Martin P.

“…Background. Plasmodium falciparum infection during pregnancy is associated with stillbirth, fetal growth restriction, and low birth weight. An additional…”
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Reduced Cord Blood Immune Effector-Cell Responsiveness Mediated by CD4+ Cells Induced in Utero as a Consequence of Placental Plasmodium falciparum Infection by Brustoski, Kim, Möller, Ulrike, Kramer, Martin, Hartgers, Franca C., Kremsner, Peter G., Krzych, Urszula, Luty, Adrian J. F.

“…To determine mechanisms of neonatal parasite antigen (Ag)–specific immune suppression associated with placental Plasmodium falciparum infection, we isolated…”
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Schistosoma haematobium infection affects Plasmodium falciparum-specific IgG responses associated with protection against malaria by COURTIN, D, DJILALI-SAÏAH, A, MILET, J, SOULARD, V, GAYE, O, MIGOT-NABIAS, F, SAUERWEIN, R, GARCIA, A, LUTY, A.J.F

“…We have previously shown that antibody responses directed to Plasmodium falciparum merozoite surface protein (MSP)-1, MSP-2 and glutamate-rich protein (GLURP)…”
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Safety and Enhanced Immunogenicity of a Hepatitis B Core Particle Plasmodium falciparum Malaria Vaccine Formulated in Adjuvant Montanide ISA 720 in a Phase I Trial by Oliveira, Giane A, Wetzel, Kristiane, Calvo-Calle, J. Mauricio, Nussenzweig, Ruth, Schmidt, Annette, Birkett, Ashley, Dubovsky, Filip, Tierney, Eveline, Gleiter, Christoph H, Boehmer, Gabriele, Luty, Adrian J. F, Ramharter, Michael, Thornton, George B, Kremsner, Peter G, Nardin, Elizabeth H

“…Highly purified subunit vaccines require potent adjuvants in order to elicit optimal immune responses. In a previous phase I trial, an alum formulation of…”
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Association of In Utero Sensitization to Schistosoma haematobium with Enhanced Cord Blood IgE and Increased Frequencies of CD sub(5) - B Cells in African Newborns by Seydel, L S, Petelski, A, van Dam, GJ, van der Kleij, D, Kruize-Hoeksma, YCM, Luty, AJF, Yazdanbakhsh, M, Kremsner, P G

“…This study investigated in utero priming as a consequence of maternal parasitic infections. Cord blood plasma samples of 63 African newborns were assessed by…”
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The Sickle Cell Trait Is Associated with Enhanced Immunoglobulin G Antibody Responses to Plasmodium falciparum Variant Surface Antigens by Cabrera, Gerardo, Cot, Michel, Migot-Nabias, Florence, Kremsner, Peter G., Deloron, Philippe, Luty, Adrian J. F.

“…The sickle cell trait (HbAS) protects against severe Plasmodium falciparum malaria in young African children. We investigated the extent of the association…”
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Mosaics of gene variations in the Interleukin-10 gene promoter affect interleukin-10 production depending on the stimulation used by Mörmann, M, Rieth, H, Hua, T D, Assohou, C, Roupelieva, M, Hu, S L, Kremsner, P G, Luty, A J F, Kube, D

“…Interleukin-10 (IL-10), a cytokine involved in many aspects of the immune response shows interindividual variations in their expression. However, genetic…”
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Low Interleukin-12 Activity in Severe Plasmodium falciparum Malaria by LUTY, A. J. F, PERKINS, D. J, WEINBERG, J. B, KREMSNER, P. G, LELL, B, SCHMIDT-OTT, R, LEHMAN, L. G, LUCKNER, D, GREVE, B, MATOUSEK, P, HERBICH, K, SCHMID, D

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IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria by Brustoski, Kim, Möller, Ulrike, Kramer, Martin, Petelski, Annika, Brenner, Stephan, Palmer, Dupeh R, Bongartz, Martina, Kremsner, Peter G, Luty, Adrian J F, Krzych, Urszula

“…Available evidence suggests that immune cells from neonates born to mothers with placental Plasmodium falciparum (Pf) infection are sensitized to parasite Ag…”
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Interferon-γ Responses Are Associated with Resistance to Reinfection with Plasmodium falciparum in Young African Children by Luty, Adrian J. F., Lell, Bertrand, Schmidt-Ott, Ruprecht, Lehman, Leopold G., Luckner, Doris, Greve, Bernhard, Matousek, Peter, Herbich, Klaus, Schmid, Daniela, Migot-Nabias, Florence, Deloron, Philippe, Nussenzweig, Ruth S., Kremsner, Peter G.

“…The contribution of T cell-mediated responses was studied with regard to resistance to reinfection in groups of Gabonese children participating in a…”
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Plasma Interleukin-10: Tumor Necrosis Factor (TNF)—α Ratio Is Associated with TNF Promoter Variants and Predicts Malarial Complications by May, Jürgen, Lell, Bertrand, Luty, Adrian J. F., Meyer, Christian G., Kremsner, Peter G.

“…In individuals with severe malarial anemia, plasma levels of tumor necrosis factor (TNF)—α tend to exceed those of interleukin (IL)—10. In this study,…”
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Neonatal and Maternal Immunological Responses to Conserved Epitopes within the DBL- gamma 3 Chondroitin Sulfate A-Binding Domain of Plasmodium falciparum Erythrocyte Membrane Protein 1 by Brustoski, Kim, Kramer, Martin, Moeller, Ulrike, Kremsner, Peter G, Luty, Adrian JF

“…Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) mediates the adherence of P. falciparum-infected erythrocytes to placental syncytiotrophoblasts…”
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New Approach for High-Throughput Screening of Drug Activity on Plasmodium Liver Stages by GEGO, Audrey, SILVIE, Olivier, FRANETICH, Jean-Francois, FARHATI, Khemaïs, HANNOUN, Laurent, LUTY, Adrian J. F, SAUERWEIN, Robert W, BOUCHEIX, Claude, RUBINSTEIN, Eric, MAZIER, Dominique

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Fcγ receptor‐mediated phagocytosis of Plasmodium falciparum‐infected erythrocytes in vitro by TEBO, A. E., KREMSNER, P. G., LUTY, A. J. F.

“…Summary Although convincing evidence exists for the role of immunoglobulin G (IgG) antibodies in immunity to malaria, antibody titres do not usually predict…”
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Activation status of cord blood gamma delta T cells reflects in utero exposure to Plasmodium falciparum antigen by Engelmann, Ilka, Santamaria, Andrea, Kremsner, Peter G, Luty, Adrian J F

“…Placental Plasmodium falciparum infection modulates neonatal cell-mediated immune responses and is associated with increased susceptibility of infants to…”
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Influenza virosomes: a flu jab for malaria? by Cavanagh, David R, Remarque, Edmond J, Sauerwein, Robert W, Hermsen, Cornelus C, Luty, Adrian J.F

“…The major attractions of vaccines based on viral carriers (vectors) include their immunogenicity without adjuvant and the relative simplicity of their…”
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Association of haptoglobin levels with age, parasite density, and haptoglobin genotype in a malaria-endemic area of Gabon by Fowkes, Freya J I, Imrie, Heather, Migot-Nabias, Florence, Michon, Pascal, Justice, Anita, Deloron, Phillipe, Luty, Adrian J F, Day, Karen P

“…Haptoglobin (Hp) levels were investigated in relation to host genotype in a malaria-endemic area in Gabon. A cross-sectional study of 1-12-year-old children…”
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Reduced Cord Blood Immune Effector-Cell Responsiveness Mediated by CD4 super(+) Cells Induced in Utero as a Consequence of Placental Plasmodium falciparum Infection by Brustoski, K, Moeller, U, Kramer, M, Hartgers, F C, Kremsner, P G, Krzych, U, Luty, AJF

“…To determine mechanisms of neonatal parasite antigen (Ag)-specific immune suppression associated with placental Plasmodium falciparum infection, we isolated…”
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