Search Results - "Lutton, John D"

Zinc Porphyrins: Potent Inhibitors of Hematopoieses in Animal and Human Bone Marrow by Lutton, John D., Abraham, Nader G., Drummond, George S., Levere, Richard D., Kappas, Attallah

“…The effects of selected heme analogues on heme oxygenase activity in tissues and on human and rabbit bone marrow hematopoietic colony growth were examined…”
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Leukemia cells and the cytokine network: therapeutic prospects by Moqattash, Satei, Lutton, John D

“…The network and balance of cytokines is of major importance in maintaining proper homeostasis of hematopoiesis. Abnormalities in this network may result in a…”
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Circulating natural IgM antibodies and their corresponding human cord blood cell–derived Mabs specifically combat the Tat protein of HIV by Rodman, Toby C, Lutton, John D, Jiang, Shanlong, Al-Kouatly, Huda B, Winston, Ronald

“…IgM antibodies reactive with each of two specifically defined sequences of HIV Tat protein have been identified in sera from both HIV + and normal (HIV −)…”
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Dual role of heme oxygenase in epithelial cell injury: Contrasting effects of short-term and long-term exposure to oxidant stress by Da Silva, Jean-Louis, Morishita, Tomoyuki, Escalante, Bruno, Staudinger, Robert, Drummond, George, Goligorsky, Michael S, Lutton, John D, Abraham, Nader G

“…This study examined the role of heme oxygenase (HO) in the acquisition of resistance to hydrogen peroxide (H 2O 2) and hemin toxicity by renal epithelial cells…”
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Developmental expression of cytochrome P450s within intrasplenically transplanted fetal hepatocytes from spontaneously hypertensive rats by Kato, K, Hodgson, W J, Lutton, J D, Abraham, N G

“…Fetal hepatocytes were harvested at 20 days of gestation from spontaneously hypertensive rats (SHR) and then transplanted into recipient adult SHR spleens…”
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Suppression of erythroid-colony formation by lymphocytes from patients with aplastic anemia by Hoffman, R, Zanjani, E D, Lutton, J D, Zalusky, R, Wasserman, L R

“…To explore the possible role of cell-mediated suppression of erythropoiesis in acquired aplastic anemia, we studied the effect of peripheral blood lymphocytes…”
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Decreased in vivo and in vitro colony stimulating activity responses to bacterial lipopolysaccharide in C3H/HeJ mice by Russo, M, Lutton, J D

“…Mice of the C3H/HeJ strain exhibit low inflammatory and immunological responses to certain bacterial lipopolysaccharide (LPS) preparations. Lymphocytes from…”
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Osteoclast demise in the rat: physiological versus degenerative cell death by Lutton, J D, Moonga, B S, Dempster, D W

“…Time-lapse video microscopy was used to assess the temporal morphological events undergone by rat osteoclasts after exposure to a variety of agents that…”
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Modulation of Erythropoiesis by Novel Human Bone Marrow Cytochrome P450-Dependent Metabolites of Arachidonic Acid by Abraham, Nader G., Feldman, Eric, Falck, John R., Lutton, John D., Schwartzman, Michel Laniado

“…In the hematopoietic system the adherent stromal cells produce cytokines necessary for proliferation and differentiation of hematopoietic cells. In the present…”
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Additive Effect of Erythropoietin and Heme on Murine Hematopoietic Recovery After Azidothymidine Treatment by Harrison, Jonathan, Kappas, Attallah, Levere, Richard D., Lutton, John D., Chertkov, Joseph L., Jiang, Shanlong, Abraham, Nader G.

“…The ability of combination treatment with erythropoietin (Epo) and heme to rescue hematopoietic activity in mice from the suppressive effect of azidothymidine…”
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Effect of blood substitute, recombinant hemoglobin, on in vivo hematopoietic recovery from AZT toxicity by Moqattash, S, Lutton, J D, Rosenthal, G, Abu-Hijleh, M F, Abraham, N G

“…We determined the in vivo ability of infused human recombinant hemoglobin 1.1 (hr-Hb) and erythropoietin to rescue the hematopoietic activity from the…”
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Mechanisms of differentiation of U937 leukemic cells induced by GM-CSF and 1,25(OH)2 vitamin D3 by Kim, Y R, Abraham, N G, Lutton, J D

“…The human monoblast cell line, U937, was employed to elucidate early events associated with differentiation induced by granulocyte-macrophage…”
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Differential effects of iron and iron carrier on hematopoietic cells differentiation and human ADA gene transfer by Abraham, N G, Lutton, J D

“…The role of iron and heme was examined in bone marrow cells from iron-deficient and chronically iron-overloaded rats. Erythroid colony cultures (CFU-E)…”
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Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells by Lutton, J D, Griffin, M O, Nishimura, M, Levere, R D, Kappas, A, Abraham, N G, Shibahara, S

“…Exposure of Hep3B cells to metalloporphyrins (tinprotoporphyrin and heme) or cobalt chloride resulted in the production of a significant number of heme…”
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Modulation of growth supportive and oncogenic properties of murine leukemia cells by Moqattash, S, Abraham, N G, Lutton, J D

“…A leukemoid reaction occurs after inoculation of L1210 leukemic cells into recipient mice and the degree of granulocytosis is correlated with tumor…”
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Synergistic effect of heme and IL-1 on hematopoietic stromal regeneration after radiation by Lutton, J D, Chertkov, J L, Jiang, S, Kappas, A, Levere, R D, Abraham, N G

“…Results from this study show that a combination of heme and interleukin-1 (IL-1) treatment resulted in the most improved recovery of hematopoietic-stromal…”
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The role of haem biosynthetic and degradative enzymes in erythroid colony development: the effect of haemin by Ibrahim, N G, Lutton, J D, Levere, R D

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Modulation of human hemopoietic progenitor cell growth in vitro by recombinant human β-interferon by SHU-JUN LIU, ASCENSAO, J. L, LUTTON, J. D, LINCOLN, R

“…Interferons are known to have modulatory effects on hemopoiesis. Human bone marrow mononuclear cells were employed to test the effects of human recombinant…”
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Diamond-Blackfan Syndrome: Lymphocyte-Mediated Suppression of Erythropoiesis by Hoffman, Ronald, Zanjani, Esmail D., Vila, Jose, Zalusky, Ralph, Lutton, John D., Wasserman, Louis R.

“…Peripheral blood lymphocytes from six patients with congenital hypoplastic anemia suppressed erythroid cell formation by normal human bone marrow cells in…”
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Endogenous erythroid colony formation by peripheral blood mononuclear cells from patients with myelofibrosis and polycythemia vera by Lutton, J D, Levere, R D

“…Peripheral blood mononuclear cells from patients with polycythemia vera or myelofibrosis with myeloid metaplasia were studied for their erythroid colony growth…”
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