Search Results - "Lutolf, M.P."

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling by Ehrbar, M., Sala, A., Lienemann, P., Ranga, A., Mosiewicz, K., Bittermann, A., Rizzi, S.C., Weber, F.E., Lutolf, M.P.

“…Reductionist in vitro model systems which mimic specific extracellular matrix functions in a highly controlled manner, termed artificial extracellular matrices…”
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Artificial niches that direct stem cell fate by Lutolf, M.P

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Cell-Responsive Synthetic Hydrogels by Lutolf, M.P., Raeber, G.P., Zisch, A.H., Tirelli, N., Hubbell, J.A.

“…Synthetic biomaterial matrices have been formed in the presence of cells by a Michael‐type addition reaction between a difunctional protease substrate peptide,…”
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Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment by Vardar, E., Larsson, H.M., Allazetta, S., Engelhardt, E.M., Pinnagoda, K., Vythilingam, G., Hubbell, J.A., Lutolf, M.P., Frey, P.

“…[Display omitted] Endoscopic injection of bulking agents has been widely used to treat urinary incontinence, often due to urethral sphincter complex…”
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The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides by Fittkau, M.H, Zilla, P, Bezuidenhout, D, Lutolf, M.P, Human, P, Hubbell, J.A, Davies, N

“…The ability of the biomimetic peptides YIGSR, PHSRN and RGD to selectively affect adhesion and migration of human microvascular endothelial cells (MVEC) and…”
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Extracellular matrix requirements for gastrointestinal organoid cultures by Rezakhani, S., Gjorevski, N., Lutolf, M.P.

“…Organoids are a new class of biological model systems that have garnered significant interest in the life sciences. When provided with the proper 3D matrix and…”
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Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures by Decembrini, S., Hoehnel, S., Brandenberg, N., Arsenijevic, Y., Lutolf, M. P.

“…The development of improved methods to culture retinal organoids is relevant for the investigation of mechanisms of retinal development under…”
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Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering by Hubbell, J A, Lutolf, M P

“…New generations of synthetic biomaterials are being developed at a rapid pace for use as three-dimensional extracellular microenvironments to mimic the…”
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Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture by Gilbert, P.M, Havenstrite, K.L, Magnusson, K.E.G, Sacco, A, Leonardi, N.A, Kraft, P, Nguyen, N.K, Thrun, S, Lutolf, M.P, Blau, H.M

“…Stem cells that naturally reside in adult tissues, such as muscle stem cells (MuSCs), exhibit robust regenerative capacity in vivo that is rapidly lost in…”
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Molecularly Engineered PEG Hydrogels: A Novel Model System for Proteolytically Mediated Cell Migration by Raeber, G.P., Lutolf, M.P., Hubbell, J.A.

“…Model systems mimicking the extracellular matrix (ECM) have greatly helped in quantifying cell migration in three dimensions and elucidated the molecular…”
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A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence by Vardar, E., Vythilingam, G., Pinnagoda, K., Engelhardt, E.M., Zambelli, P.Y., Hubbell, J.A., Lutolf, M.P., Frey, P., Larsson, H.M.

“…Stress urinary incontinence (SUI) is a life changing condition, affecting 20 million women worldwide. In this study, we developed a bioactive, injectable…”
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Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs by Raeber, G.P., Lutolf, M.P., Hubbell, J.A.

“…The elucidation of molecular cell–extracellular matrix (ECM) interactions regulating tissue dynamics necessitates straightforward model systems that can…”
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Poly(ethylene glycol) block copolymers by Tirelli, N, Lutolf, M.P, Napoli, A, Hubbell, J.A

“…The ubiquitous use of poly(ethylene glycol) in the biomaterials field has also boosted the research activity in the chemical derivatization of this polymer. We…”
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