Search Results - "Luthin, David R"

Anti-obesity effects of small molecule melanin-concentrating hormone receptor1 (MCHR1) antagonists by Luthin, David R.

“…Over the past ten years, tremendous advances in our understanding of the role of the hypothalamic neurohormone, melanin-concentrating hormone (MCH), and its…”
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Current and Emerging Treatments for Irritable Bowel Syndrome with Constipation and Chronic Idiopathic Constipation: Focus on Prosecretory Agents by Thomas, Rachel H., Luthin, David R.

“…Irritable bowel syndrome with constipation (IBS‐C) and chronic idiopathic constipation (CIC) are two common functional gastrointestinal disorders that impair…”
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Biological characterization of a novel, orally active small molecule gonadotropin-releasing hormone (GnRH) antagonist using castrated and intact rats by Anderes, Kenna L, Luthin, David R, Castillo, Rosemary, Kraynov, Eugenia A, Castro, Mary, Nared-Hood, Karen, Gregory, Margaret L, Pathak, Ved P, Christie, Lance C, Paderes, Genevieve, Vazir, Haresh, Ye, Qiang, Anderson, Mark B, May, John M

“…Gonadotropin-releasing hormone (GnRH) receptor antagonists have potential in treating numerous hormone-dependent pathologies including cancers of the prostate,…”
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Impact of an inter-professional concussion awareness program for intramural athletes on students’ readiness for inter-professional learning by Luthin, David R, Holston, Jane T, Adams-Mitchell, Candice J

“…AbstractSports-related concussions are the third leading cause of traumatic brain injuries in student athletes throughout the country. In a survey of all NCAA…”
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Linaclotide: A Novel Approach to the Treatment of Irritable Bowel Syndrome by Wensel, Terri M, Luthin, David R

“…Objective: To review the pharmacology, pharmacokinetics, efficacy, and safety of linaclotide for irritable bowel syndrome (IBS). Data Sources: A literature…”
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Wheel access does not attenuate weight gain in mice fed high-fat or high-CHO diets by Jung, Alan P, Luthin, David R

“…To determine the effect of a high-fat or high-carbohydrate diet and running wheel activity on body composition, body mass, and caloric intake in C57Bl/6 mice…”
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D-cycloserine in the treatment of posttraumatic stress disorder by Baker, Joni F, Cates, Marshall E, Luthin, David R

“…Posttraumatic stress disorder (PTSD) is a common and serious psychiatric illness. Exposure therapy is a type of cognitive behavioral therapy that is considered…”
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Parental perspectives of diabetes management in Alabama public schools by Skelley, Jason P, Luthin, David R, Skelley, Jessica W, Kabagambe, Edmond K, Ashraf, Ambika P, Atchison, Joycelyn A

“…The purpose of this study was to assess parental perceptions of the current state of care for children with diabetes in the Alabama public school system,…”
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Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist by Li, Haitao, Anderes, Kenna L, Kraynov, Eugenia A, Luthin, David R, Do, Quyen-Quyen, Hong, Yufeng, Tompkins, Eileen, Sun, Eric T, Rajapakse, Ranjan, Pathak, Ved P, Christie, Lance C, Vazir, Haresh, Castillo, Rosemary, Gregory, Margaret L, Castro, Mary, Nared-Hood, Karen, Paderes, Genevieve, Anderson, Mark B

“…Gonadotropin releasing hormone (GnRH) plays an important role in the biology of reproduction. The use of GnRH receptor antagonists has been reported in the…”
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Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist by Li, Haitao, Anderes, Kenna L, Kraynov, Eugenia A, Luthin, David R, Do, Quyen-Quyen, Hong, Yufeng, Tompkins, Eileen, Sun, Eric T, Rajapakse, Ranjan, Pathak, Ved P, Christie, Lance C, Feng, Jun, Vazir, Haresh, Castillo, Rosemary, Gregory, Margaret L, Castro, Mary, Nared-Hood, Karen, Paderes, Genevieve, Anderson, Mark B

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Characterization of mono- and diaminopyrimidine derivatives as novel, nonpeptide gonadotropin releasing hormone (GnRH) receptor antagonists by Luthin, David R, Hong, Yufeng, Tompkins, Eileen, Anderes, Kenna L, Paderes, Genevieve, Kraynov, Eugenia A, Castro, Mary A, Nared-Hood, Karen D, Castillo, Rosemary, Gregory, Margaret, Vazir, Haresh, May, John M, Anderson, Mark B

“…A novel series of derivatives of mono- and diaminopyrimidines 1 potently displaced binding of a radiolabeled GnRH analogue to human and rat GnRH receptors…”
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The discovery of novel small molecule non-peptide gonadotropin releasing hormone (GnRH) receptor antagonists by Luthin, David R., Hong, Yufeng, Pathak, Ved P., Paderes, Genevieve, Nared-Hood, Karen D., Castro, Mary A., Vazir, Haresh, Li, Haitao, Tompkins, Eileen, Christie, Lance, May, John M., Anderson, Mark B.

“…A novel series of non-peptide derivatives 1, 14, and 15 that bind with high affinity to the human GnRH receptors is discussed. The discovery was made from…”
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Synthesis and biological activity of oxo-7H-benzo[E]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists by LUTHIN, D. R, RABINOVICH, A. K, BHUMRALKAR, D. R, YOUNGBLOOD, K. L, BYCHOWSKI, R. A, DHANOA, D. S, MAY, J. M

“…A novel series of derivatives of oxo-7H-benzo[e]perimidine-4-carboxylic acid (I) potently displaced radioligand binding of 125I-CRF to both CRF1 and CRF2…”
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Genomic Analysis and Expression Patterns Reveal Distinct Genes for Endothelial and Brain Nitric Oxide Synthase by Sessa, William C, Harrison, Jeffrey K, Luthin, David R, Pollock, Jennifer S, Lynch, Kevin R

“…Constitutively active nitric oxide synthases (NOS) are a unique class of NADPH-dependent, calcium/ caimodulin-dependent enzymes that catalyze the conversion of…”
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Anti-obesity effects of small molecule melanin-concentrating hormone receptor 1 (MCHR1) antagonists by Luthin, David R

“…Over the past ten years, tremendous advances in our understanding of the role of the hypothalamic neurohormone, melanin-concentrating hormone (MCH), and its…”
Get full text

Wheel Activity Provides No Protection Against Weight Gain in Mice Fed High-Fat or High-Carbohydrate Diets: 1893 Board #57 May 29 3:30 PM - 5:00 PM by Jung, Alan P., Luthin, David R., Penrod, Cody H., Alfaro, Christopher

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Relationship between pharmacy students' knowledge about, attitudes toward, and intention to provide pharmacy-based immunization services by Luthin, David R., King, Sean R., Wensel, Terri M., Rosser, Ashley N., Monk-Tutor, Mary R.

“…The purpose of this study was to examine pharmacy students' knowledge about, attitudes toward, and intention to provide pharmacy-based immunization services…”
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Double tagging recombinant A1- and A2A-adenosine receptors with hexahistidine and the FLAG epitope : Development of an efficient generic protein purification procedure by ROBEVA, A. S, WOODARD, R, LUTHIN, D. R, TAYLOR, H. E, LINDEN, J

“…An expression plasmid for mammalian cells (CLDN10B) has been modified to add nucleotides encoding hexahistidine and the FLAG peptide (H/F) to cDNAs. The new…”
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Effect of testosterone suppression on the pharmacokinetics of a potent GnRH receptor antagonist by IATSIMIRSKAIA, Eugenia A, GREGORY, Margaret L, MAY, John M, ANDERES, Kenna L, CASTILLO, Rosemary, MILGRAM, K. Eric, LUTHIN, David R, PATHAK, Ved P, CHRISTIE, Lance C, VAZIR, Haresh, ANDERSON, Mark B

“…The expression of cytochrome P450 enzymes (CYPs) in animals and humans is under complex hormonal regulation. Chronic treatment with drugs that alter sex…”
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Characterization of two affinity states of adenosine A2a receptors with a new radioligand, 2-[2-(4-amino-3-[125I]iodophenyl)ethylamino]adenosine by Luthin, D R, Olsson, R A, Thompson, R D, Sawmiller, D R, Linden, J

“…Adenosine analogs substituted in the 2-position with arylamino groups have been found to have high affinity and selectivity for A2a adenosine receptors. Two…”
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