Search Results - "Luthi, Anita"

Coordinated infraslow neural and cardiac oscillations mark fragility and offline periods in mammalian sleep by Lecci, Sandro, Fernandez, Laura M J, Weber, Frederik D, Cardis, Romain, Chatton, Jean-Yves, Born, Jan, Lüthi, Anita

“…Rodents sleep in bouts lasting minutes; humans sleep for hours. What are the universal needs served by sleep given such variability? In sleeping mice and…”
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T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites by Cueni, Lucius, Canepari, Marco, Luján, Rafael, Emmenegger, Yann, Watanabe, Masahiko, Bond, Chris T, Franken, Paul, Adelman, John P, Lüthi, Anita

“…T-type Ca 2+ channels (T channels) underlie rhythmic burst discharges during neuronal oscillations that are typical during sleep. However, the Ca 2+ -dependent…”
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Phasic, nonsynaptic GABA-A receptor-mediated inhibition entrains thalamocortical oscillations by Rovó, Zita, Mátyás, Ferenc, Barthó, Péter, Slézia, Andrea, Lecci, Sandro, Pellegrini, Chiara, Astori, Simone, Dávid, Csaba, Hangya, Balázs, Lüthi, Anita, Acsády, László

“…GABA-A receptors (GABA-ARs) are typically expressed at synaptic or nonsynaptic sites mediating phasic and tonic inhibition, respectively. These two forms of…”
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Sleep Spindles: Mechanisms and Functions by Fernandez, Laura M J, Lüthi, Anita

“…Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping mammalian brain and electrical surface correlates of neuronal…”
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Sleep: Switching Off the Off-Switch by Lüthi, Anita

“…What are the synaptic drives controlling the sleep–wake circuitry in the mammalian brain? In a new study it was found that GABAergic cells in posterior lateral…”
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NR2A at CA1 Synapses Is Obligatory for the Susceptibility of Hippocampal Plasticity to Sleep Loss by Longordo, Fabio, Kopp, Caroline, Mishina, Masayoshi, Lujan, Rafael, Luthi, Anita

“…A loss in the necessary amount of sleep alters expression of genes and proteins implicated in brain plasticity, but key proteins that render neuronal circuits…”
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Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures by Hammelmann, Verena, Stieglitz, Marc Sebastian, Hülle, Henrik, Le Meur, Karim, Kass, Jennifer, Brümmer, Manuela, Gruner, Christian, Rötzer, René Dominik, Fenske, Stefanie, Hartmann, Jana, Zott, Benedikt, Lüthi, Anita, Spahn, Saskia, Moser, Markus, Isbrandt, Dirk, Ludwig, Andreas, Konnerth, Arthur, Wahl-Schott, Christian, Biel, Martin

“…Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are dually gated channels that are operated by voltage and by neurotransmitters via the cAMP…”
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Contrasting the Functional Properties of GABAergic Axon Terminals with Single and Multiple Synapses in the Thalamus by Wanaverbecq, Nicolas, Bodor, Agnes L, Bokor, Hajnalka, Slezia, Andrea, Luthi, Anita, Acsady, Laszlo

“…Diverse sources of GABAergic inhibition are a major feature of cortical networks, but distinct inhibitory input systems have not been systematically…”
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When the Locus Coeruleus Speaks Up in Sleep: Recent Insights, Emerging Perspectives by Osorio-Forero, Alejandro, Cherrad, Najma, Banterle, Lila, Fernandez, Laura M J, Lüthi, Anita

“…For decades, numerous seminal studies have built our understanding of the (LC), the vertebrate brain's principal noradrenergic system. Containing a numerically…”
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Noradrenergic circuit control of non-REM sleep substates by Osorio-Forero, Alejandro, Cardis, Romain, Vantomme, Gil, Guillaume-Gentil, Aurélie, Katsioudi, Georgia, Devenoges, Christiane, Fernandez, Laura M.J., Lüthi, Anita

“…To understand what makes sleep vulnerable in disease, it is useful to look at how wake-promoting mechanisms affect healthy sleep. Wake-promoting neuronal…”
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Thalamic reticular control of local sleep in mouse sensory cortex by Fernandez, Laura Mj, Vantomme, Gil, Osorio-Forero, Alejandro, Cardis, Romain, Béard, Elidie, Lüthi, Anita

“…Sleep affects brain activity globally, but many cortical sleep waves are spatially confined. Local rhythms serve cortical area-specific sleep needs and…”
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Homeostatic regulation of rapid eye movement sleep by the preoptic area of the hypothalamus by Maurer, John J, Lin, Alexandra, Jin, Xi, Hong, Jiso, Sathi, Nicholas, Cardis, Romain, Osorio-Forero, Alejandro, Lüthi, Anita, Weber, Franz, Chung, Shinjae

“…Rapid eye movement sleep (REMs) is characterized by activated electroencephalogram (EEG) and muscle atonia, accompanied by vivid dreams. REMs is…”
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Insufficient Sleep Reversibly Alters Bidirectional Synaptic Plasticity and NMDA Receptor Function by Kopp, Caroline, Longordo, Fabio, Nicholson, Janet R, Luthi, Anita

“…Insufficient sleep impairs cognitive functions in humans and animals. However, whether long-term synaptic plasticity, a cellular substrate of learning and…”
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Regulation of Local Sleep by the Thalamic Reticular Nucleus by Vantomme, Gil, Osorio-Forero, Alejandro, Lüthi, Anita, Fernandez, Laura M J

“…In spite of the uniform appearance of sleep as a behavior, the sleeping brain does not produce electrical activities in unison. Different types of brain…”
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Do all norepinephrine surges disrupt sleep? by Lüthi, Anita, Franken, Paul, Fulda, Stephany, Siclari, Francesca, Van Someren, Eus J. W.

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The lactate receptor HCAR1: A key modulator of epileptic seizure activity by Alessandri, Maxime, Osorio-Forero, Alejandro, Lüthi, Anita, Chatton, Jean-Yves

“…Epilepsy affects millions globally with a significant portion exhibiting pharmacoresistance. Abnormal neuronal activity elevates brain lactate levels, which…”
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Consequences of sleep deprivation on neurotransmitter receptor expression and function by Longordo, Fabio, Kopp, Caroline, Lüthi, Anita

“…Several pieces of evidence suggest that sleep deprivation causes marked alterations in neurotransmitter receptor function in diverse neuronal cell types. To…”
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Cortical afferents onto the nucleus Reticularis thalami promote plasticity of low-threshold excitability through GluN2C-NMDARs by Fernandez, Laura M. J., Pellegrini, Chiara, Vantomme, Gil, Béard, Elidie, Lüthi, Anita, Astori, Simone

“…Thalamus and cortex represent a highly integrated processing unit that elaborates sensory representations. Interposed between cortex and thalamus, the nucleus…”
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Optogenetic Dissection of Sleep-Wake States In Vitro and In Vivo by Adamantidis, Antoine, Lüthi, Anita

“…Optogenetic tools have revolutionized insights into the fundamentals of brain function. This is particularly true for our current understanding of sleep-wake…”
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Diurnal inhibition of NMDA‐EPSCs at rat hippocampal mossy fibre synapses through orexin‐2 receptors by Perin, Martina, Longordo, Fabio, Massonnet, Christine, Welker, Egbert, Lüthi, Anita

“…Key points Orexins are well described for their excitatory actions on feeding‐ and arousal‐promoting brain centres; we describe here an inhibitory action of…”
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