Search Results - "Lutgens, Ludy C."
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Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer-Combined Analysis of the PORTEC Cohorts
Published in Clinical cancer research (15-08-2016)“…Recommendations for adjuvant treatment for women with early-stage endometrial carcinoma are based on clinicopathologic features. Comprehensive genomic…”
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Five-year quality of life of endometrial cancer patients treated in the randomised Post Operative Radiation Therapy in Endometrial Cancer (PORTEC-2) trial and comparison with norm data
Published in European journal of cancer (1990) (01-07-2012)“…Abstract Background The PORTEC-2 trial showed efficacy and reduced side-effects of vaginal brachytherapy (VBT) compared with external beam pelvic radiotherapy…”
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Prediction of recurrence risk in endometrial cancer with multimodal deep learning
Published in Nature medicine (24-05-2024)“…Predicting distant recurrence of endometrial cancer (EC) is crucial for personalized adjuvant treatment. The current gold standard of combined pathological and…”
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Efficacy of a nurse-led sexual rehabilitation intervention for women with gynaecological cancers receiving radiotherapy: results of a randomised trial
Published in British journal of cancer (01-09-2024)“…Background The multicentre randomised SPARC trial evaluated the efficacy of a nurse-led sexual rehabilitation intervention on sexual functioning, distress,…”
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Author Correction: Prediction of recurrence risk in endometrial cancer with multimodal deep learning
Published in Nature medicine (01-07-2024)Get full text
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Quality of Life After Pelvic Radiotherapy or Vaginal Brachytherapy for Endometrial Cancer: First Results of the Randomized PORTEC-2 Trial
Published in Journal of clinical oncology (20-07-2009)“…PURPOSE Studies on quality of life (QOL) among women with endometrial cancer have shown that patients who undergo pelvic radiotherapy report lower role…”
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Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials
Published in The lancet oncology (01-06-2024)“…Numerous studies have shown that older women with endometrial cancer have a higher risk of recurrence and cancer-related death. However, it remains unclear…”
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Monitoring myeloablative therapy-induced small bowel toxicity by serum citrulline concentration a comparison with sugar permeability tests
Published in Cancer (2005)“…Intestinal mucositis is an important cause of cancer treatment-related morbidity and mortality, carrying a serious economic burden. Currently, objective…”
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Radiotherapy and Hyperthermia for Treatment of Primary Locally Advanced Cervix Cancer: Results in 378 Patients
Published in International journal of radiation oncology, biology, physics (2009)“…Purpose To report response rate, pelvic tumor control, survival, and late toxicity after treatment with combined radiotherapy and hyperthermia (RHT) for…”
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Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer – A pooled analysis of PORTEC 1 and 2 trials
Published in European journal of cancer (1990) (01-09-2015)“…Abstract Background Lymph-vascular space invasion (LVSI) is an important adverse prognostic factor in endometrial cancer (EC). However, its role in relation to…”
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Confirmation of thermal dose as a predictor of local control in cervical carcinoma patients treated with state-of-the-art radiation therapy and hyperthermia
Published in Radiotherapy and oncology (01-11-2019)“…•Significant local control improvement in cervical cancer patients due to hyperthermia was validated in a recent patient cohort.•Hyperthermia is effective in…”
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Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer
Published in JNCI : Journal of the National Cancer Institute (04-09-2021)“…Standard screening of endometrial cancer (EC) for Lynch syndrome (LS) is gaining traction; however, the prognostic impact of an underlying hereditary etiology…”
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Defining Substantial Lymphovascular Space Invasion in Endometrial Cancer
Published in International journal of gynecological pathology (01-05-2022)“…Lymphovascular space invasion (LVSI) occurs in a minority of endometrial cancer (EC) cases, and the extent of LVSI is an important risk factor for recurrence…”
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Fifteen-Year Radiotherapy Outcomes of the Randomized PORTEC-1 Trial for Endometrial Carcinoma
Published in International journal of radiation oncology, biology, physics (15-11-2011)“…Purpose To evaluate the very long-term results of the randomized Post Operative Radiation Therapy in Endometrial Carcinoma (PORTEC)-1 trial for patients with…”
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Association of persistent morbidity after radiotherapy with quality of life in locally advanced cervical cancer survivors
Published in Radiotherapy and oncology (01-04-2023)“…•Impact of morbidity on quality of life (QOL) of cancer survivors depends on severity and persistence.•Prospective data from EMBRACE-I allowed to assess the…”
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Radiation Therapy Techniques and Treatment-Related Toxicity in the PORTEC-3 Trial: Comparison of 3-Dimensional Conformal Radiation Therapy Versus Intensity-Modulated Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-02-2022)“…Radiation therapy techniques have developed from 3-dimensional conformal radiation therapy (3DCRT) to intensity modulated radiation therapy (IMRT), with better…”
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Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future
Published in International journal of radiation oncology, biology, physics (01-03-2022)“…The purpose was to evaluate patient- and treatment-related risk factors for physician-assessed and patient-reported gastrointestinal (GI) symptoms after…”
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Long-Term Outcome and Quality of Life of Patients With Endometrial Carcinoma Treated With or Without Pelvic Radiotherapy in the Post Operative Radiation Therapy in Endometrial Carcinoma 1 (PORTEC-1) Trial
Published in Journal of clinical oncology (01-05-2011)“…To determine the long-term outcome and health-related quality of life (HRQL) of patients with endometrial carcinoma (EC) treated with or without pelvic…”
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Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer
Published in Cancer immunology research (01-12-2020)“…Optimum risk stratification in early-stage endometrial cancer combines clinicopathologic factors and the molecular endometrial cancer classification defined by…”
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Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study
Published in International journal of radiation oncology, biology, physics (01-04-2022)“…This study aimed to evaluate patient- and treatment-related risk factors for late persistent fatigue within the prospective, multicenter EMBRACE-I study…”
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