Search Results - "Lusky, M"

Vaccinia-based oncolytic immunotherapy Pexastimogene Devacirepvec in patients with advanced hepatocellular carcinoma after sorafenib failure: a randomized multicenter Phase IIb trial (TRAVERSE) by Moehler, M., Heo, J., Lee, H.C., Tak, W.Y., Chao, Y., Paik, S.W., Yim, H.J., Byun, K.S., Baron, A., Ungerechts, G., Jonker, D., Ruo, L., Cho, M., Kaubisch, A., Wege, H., Merle, P., Ebert, O., Habersetzer, F., Blanc, J.F., Rosmorduc, Olivier, Lencioni, R., Patt, R., Leen, A.M., Foerster, F., Homerin, M., Stojkowitz, N., Lusky, M., Limacher, J.M., Hennequi, M., Gaspar, N., McFadden, B., De Silva, N., Shen, D., Pelusio, A., Kirn, D.H., Breitbach, C.J., Burke, J.M.

“…Pexastimogene devacirepvec (Pexa-Vec) is a vaccinia virus-based oncolytic immunotherapy designed to preferentially replicate in and destroy tumor cells while…”
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Immunogenicity of oncolytic vaccinia viruses JX-GFP and TG6002 in a human melanoma in vitro model: studying immunogenic cell death, dendritic cell maturation and interaction with cytotoxic T lymphocytes by Heinrich, B, Klein, J, Delic, M, Goepfert, K, Engel, V, Geberzahn, L, Lusky, M, Erbs, P, Preville, X, Moehler, M

“…Oncolytic virotherapy is an emerging immunotherapeutic modality for cancer treatment. Oncolytic viruses with genetic modifications can further enhance the…”
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2219 Intratumoral injection of the oncolytic immunotherapeutic Pexa-Vec (JX-594) in liver tumors and hepatocellular carcinoma: Recommendations for clinical practice by Lencioni, R, Kim, C.W, Rose, S.C, Breitbach, C.J, Burke, J.M, Hickman, T, Kirn, D.H, Stojkowitz, N, Lusky, M, Homerin, M

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In Vitro and In Vivo Biology of Recombinant Adenovirus Vectors with E1, E1/E2A, or E1/E4 Deleted by Lusky, M, Christ, M, Rittner, K, Dieterle, A, Dreyer, D, Mourot, B, Schultz, H, Stoeckel, F, Pavirani, A, Mehtali, M

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Targeting of adenovirus vectors carrying a tumor cell-specific peptide: in vitro and in vivo studies by Rittner, K, Schreiber, V, Erbs, P, Lusky, M

“…Previously, we have identified a tumor cell-specific peptide, HEW, by panning of phage display libraries on the human colorectal cancer cell line WiDr. In this…”
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The use of fibrin adhesive in trabeculectomy: a pilot study by Bahar, I, Lusky, M, Gaton, D, Robinson, A, Avisar, R, Weinberger, D

“…To overcome these problems, investigators have suggested the use of laser suture lysis 1 or releasable sutures 2 or other types of closure methods, such as…”
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Regulation of Adenovirus-Mediated Transgene Expression by the Viral E4 Gene Products: Requirement for E4 ORF3 by Lusky, M, Grave, L, Dieterlé, A, Dreyer, D, Christ, M, Ziller, C, Furstenberger, P, Kintz, J, Hadji, D A, Pavirani, A, Mehtali, M

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Pupillary block following posterior chamber intraocular lens implantation in adults by Gaton, D D, Mimouni, K, Lusky, M, Ehrlich, R, Weinberger, D

“…Background: Pupillary block rarely occurs after cataract extraction with posterior chamber intraocular lens implantation. Methods: A series of six patients…”
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Augmented trabeculectomy in paediatric glaucoma by Ehrlich, R, Snir, M, Lusky, M, Weinberger, D, Friling, R, Gaton, D D

“…Aims: To report the experience with trabeculectomy augmented with mitomycin C and 5-fluorouracil for the treatment of paediatric glaucoma. Methods:…”
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Bovine papilloma virus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication by Seo, Y.S. (Sloan-Kettering Cancer Center, New York, NY), Muller, F, Lusky, M, Hurwitz, J

“…Replication of bovine papilloma virus (BPV) DNA requires two virus-encoded proteins, E1 and E2, while all other proteins are supplied by the host cell. Here,…”
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Formation of the complex of bovine papillomavirus E1 and E2 proteins is modulated by E2 phosphorylation and depends upon sequences within the carboxyl terminus of E1 by Lusky, M. (Cornell University Medical College, New York, NY), Fontane, E

“…The 68-kDa bovine papillomavirus (BPV) type 1 replication protein E1 and the 48-kDa transactivator protein E2 form a complex that specifically binds DNA [Mohr,…”
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Short-wavelength color visual fields in glaucoma suspects at risk by Sample, P A, Taylor, J D, Martinez, G A, Lusky, M, Weinreb, R N

“…Glaucoma suspect eyes were seen during a five-year study on color visual fields that used a 440-nm test on a bright-yellow background (96 normal eyes, 55…”
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Bovine Papilloma Virus (BPV)-Encoded E2 Protein Enhances Binding of E1 Protein to the BPV Replication Origin by Seo, Yeon-Soo, Muller, Friedemann, Lusky, Monika, Gibbs, Emma, Kim, Hae-Yeong, Phillips, Barbara, Hurwitz, Jerard

“…The replication of bovine papilloma virus (BPV) DNA in vivo requires two viral-encoded proteins, E1 and E2, while all other proteins are derived from the host…”
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Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteins by Gillette, T.G, Lusky, M, Borowiec, J.A

“…Chemical and enzymatic probing techniques were used to examine the interaction of the bovine papillomavirus type 1 E1 and E2 proteins with the viral origin of…”
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Cooperative assembly of the bovine papilloma virus E1 and E2 proteins on the replication origin requires an intact E2 binding site by Lusky, M, Hurwitz, J, Seo, Y.S

“…Using quantitative gel retardation assays the properties of the bovine papilloma virus (BPV) origin recognition protein E1 and the effect of the viral E2…”
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The bovine papillomavirus E2 protein modulates the assembly of but is not stably maintained in a replication-competent multimeric E1-replication origin complex by Lusky, M, Hurwitz, J, Seo, Y.S

“…Initiation of bovine papillomavirus (BPV) DNA synthesis in vivo and in vitro depends on the interaction of the viral initiator protein E1 with the replication…”
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Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy by Lerondel, S, Le Pape, A, Sené, C, Faure, L, Bernard, S, Diot, P, Nicolis, E, Mehtali, M, Lusky, M, Cabrini, G, Pavirani, A

“…Cystic fibrosis is a common, heriditary disease resulting from mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Airway…”
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Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors by LUSKY, M, BOTCHAN, M. R

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A phase Ib trial of JX-594 (Pexa-Vec), a targeted multimechanistic oncolytic vaccinia virus, in combination with low-dose cyclophosphamide in patients with advanced solid tumors by Toulmonde, M., Cousin, S., Bessede, A., Homerin, M., Stojkowitz, N., Lusky, M., Pulido, M., Italiano, A.

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Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit [Model system] by Lusky, M, Berg, L, Weiher, H, Botchan, M

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