Search Results - "Lusczek, Elizabeth"
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Characterizing COVID-19 clinical phenotypes and associated comorbidities and complication profiles
Published in PloS one (31-03-2021)“…Heterogeneity has been observed in outcomes of hospitalized patients with coronavirus disease 2019 (COVID-19). Identification of clinical phenotypes may…”
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Urinary metabolites predict mortality or need for renal replacement therapy after combat injury
Published in Critical care (London, England) (23-03-2021)“…Traditionally, patient risk scoring is done by evaluating vital signs and clinical severity scores with clinical intuition. Urinary biomarkers can add…”
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Minimizing bias when using artificial intelligence in critical care medicine
Published in Journal of critical care (01-08-2024)“…•As artificial intelligence (AI) use in critical care increases, identifying and minimizing sources of bias is essential•Bias can be introduced (and be…”
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Hibernation-Based Approaches in the Treatment of Hemorrhagic Shock
Published in Shock (Augusta, Ga.) (01-07-2018)“…ABSTRACTHemorrhagic shock is the leading cause of preventable death after trauma. Hibernation-based treatment approaches have been of increasing interest for…”
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Plasma metabolomics pilot study suggests age and sex-based differences in the metabolic response to traumatic injury
Published in Injury (01-12-2018)“…Age and sex affect outcomes from trauma. Older patients tend to be under-triaged, consume more healthcare resources, and experience worse outcomes relative to…”
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Correction: Chronic Alcohol Ingestion Increases Mortality and Organ Injury in a Murine Model of Septic Peritonitis
Published in PloS one (17-09-2020)“…[This corrects the article DOI: 10.1371/journal.pone.0062792.]…”
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Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement
Published in American journal of respiratory and critical care medicine (01-04-2023)“…Sleep and circadian disruption (SCD) is common and severe in the ICU. On the basis of rigorous evidence in non-ICU populations and emerging evidence in ICU…”
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Enhancing cosinor analysis of circadian phase markers using the gamma distribution
Published in Sleep medicine (01-04-2022)“…The cosinor model, in which a cosine curve is fitted to periodic data within a regression model, is a frequently used method for describing patterns of…”
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Assessment of key plasma metabolites in combat casualties
Published in The journal of trauma and acute care surgery (01-02-2017)“…Previous studies have indicated that hemorrhagic shock and injury cause significant early changes in metabolism. Recently, global changes in metabolism have…”
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Chronic alcohol ingestion increases mortality and organ injury in a murine model of septic peritonitis
Published in PloS one (22-05-2013)“…Patients admitted to the intensive care unit with alcohol use disorders have increased morbidity and mortality. The purpose of this study was to determine how…”
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Light Levels in ICU Patient Rooms: Dimming of Daytime Light in Occupied Rooms
Published in Journal of patient experience (2021)“…One-third of patients report disruption of sleep by overnight light. Importantly, light causes both immediate sleep disturbance and influences circadian…”
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Risk Factors of Mortality for Patients Receiving Venovenous Extracorporeal Membrane Oxygenation for COVID-19 Acute Respiratory Distress Syndrome
Published in Surgical infections (01-12-2021)“…Venovenous extracorporeal membrane oxygenation (VV-ECMO) for select adults with severe acute respiratory distress syndrome (ARDS) cause by coronavirus disease…”
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Perioperative Coagulation Changes in Total Pancreatectomy and Islet Autotransplantation
Published in Pancreas (01-07-2022)“…Objectives Thrombotic complications after total pancreatectomy with islet autotransplantation (TPIAT) are common. However, the systemic changes to coagulation…”
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The Use of Venovenous Extracorporeal Membrane Oxygenation in COVID-19 Infection: One Region’s Comprehensive Experience
Published in ASAIO journal (1992) (01-05-2021)“…Severe acute respiratory distress syndrome (ARDS) unresponsive to conventional intensive care unit (ICU) management is an accepted indication for venovenous…”
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Development of a proteomic signature associated with severe disease for patients with COVID-19 using data from 5 multicenter, randomized, controlled, and prospective studies
Published in Scientific reports (20-11-2023)“…Significant progress has been made in preventing severe COVID-19 disease through the development of vaccines. However, we still lack a validated baseline…”
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Evaluation of Minnesota Score in the Allocation of Venovenous Extracorporeal Membrane Oxygenation During Resource Scarcity
Published in Critical care research and practice (06-04-2022)“…Background. In this study, we evaluate the previously reported novel Minnesota Score for association with in-hospital mortality and allocation of venovenous…”
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Metabolomics Pilot Study Identifies Desynchronization of 24-H Rhythms and Distinct Intra-patient Variability Patterns in Critical Illness: A Preliminary Report
Published in Frontiers in neurology (02-10-2020)“…Background: Synchronized circadian rhythms play a key role in coordinating physiologic health. Desynchronized circadian rhythms may predispose individuals to…”
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A four-compartment metabolomics analysis of the liver, muscle, serum, and urine response to polytrauma with hemorrhagic shock following carbohydrate prefeed
Published in PloS one (14-04-2015)“…Hemorrhagic shock accompanied by injury represents a major physiologic stress. Fasted animals are often used to study hemorrhagic shock (with injury). A fasted…”
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Metabolomics in COPD Acute Respiratory Failure Requiring Noninvasive Positive Pressure Ventilation
Published in Canadian respiratory journal (01-01-2017)“…We aimed to investigate whether metabolomic analysis can discriminate acute respiratory failure due to COPD exacerbation from respiratory failure due to heart…”
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