Search Results - "Luque, Irene"

Study of the Applicability Domain of the QSAR Classification Models by Means of the Rivality and Modelability Indexes by Ruiz, Irene Luque, Gómez-Nieto, Miguel Ángel

“…The reliability of a QSAR classification model depends on its capacity to achieve confident predictions of new compounds not considered in the building of the…”
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State of the Art, Trends and Future of Bluetooth Low Energy, Near Field Communication and Visible Light Communication in the Development of Smart Cities by Cerruela García, Gonzalo, Luque Ruiz, Irene, Gómez-Nieto, Miguel Ángel

“…The current social impact of new technologies has produced major changes in all areas of society, creating the concept of a smart city supported by an…”
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Expert Consensus Guidelines on Minimally Invasive Donor Hepatectomy for Living Donor Liver Transplantation From Innovation to Implementation: A Joint Initiative From the International Laparoscopic Liver Society (ILLS) and the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA) by Cherqui, Daniel, Ciria, Ruben, Kwon, Choon Hyuck David, Kim, Ki-Hun, Broering, Dieter, Wakabayashi, Go, Samstein, Benjamin, Troisi, Roberto I., Han, Ho Seong, Rotellar, Fernando, Soubrane, Olivier, Briceño, Javier, Alconchel, Felipe, Ayllón, María Dolores, Berardi, Giammauro, Cauchy, Francois, Luque, Irene Gómez, Hong, Suk Kyun, Yoon, Young-Yin, Egawa, Hiroto, Lerut, Jan, Lo, Chung-Mau, Rela, Mohamed, Sapisochin, Gonzalo, Suh, Kyung-Suk

“…The Expert Consensus Guidelines initiative on MIDH for LDLT was organized with the goal of safe implementation and development of these complex techniques with…”
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Splicing factor SF3B1 is overexpressed and implicated in the aggressiveness and survival of hepatocellular carcinoma by López-Cánovas, Juan L., del Rio-Moreno, Mercedes, García-Fernandez, Helena, Jiménez-Vacas, Juan M., Moreno-Montilla, M.Trinidad, Sánchez-Frias, Marina E., Amado, Víctor, L-López, Fernando, Fondevila, Marcos F., Ciria, Rubén, Gómez-Luque, Irene, Briceño, Javier, Nogueiras, Rubén, de la Mata, Manuel, Castaño, Justo P., Rodriguez-Perálvarez, Manuel, Luque, Raúl M., Gahete, Manuel D.

“…Splicing alterations represent an actionable cancer hallmark. Splicing factor 3B subunit 1 (SF3B1) is a crucial splicing factor that can be targeted…”
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Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein–protein interaction domains by Zafra-Ruano, Ana, Luque, Irene

“…The recognition of proline-rich sequences by protein–protein interaction modules is essential for many cellular processes. Nonetheless, in spite of the wealth…”
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The Strawberry Pathogenesis-related 10 (PR-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding to Metabolic Intermediates by Casañal, Ana, Zander, Ulrich, Muñoz, Cristina, Dupeux, Florine, Luque, Irene, Botella, Miguel Angel, Schwab, Wilfried, Valpuesta, Victoriano, Marquez, José A.

“…Pathogenesis-related 10 (PR-10) proteins are involved in many aspects of plant biology but their molecular function is still unclear. They are related by…”
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WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands by Iglesias-Bexiga, Manuel, Castillo, Francisco, Cobos, Eva S, Oka, Tsutomu, Sudol, Marius, Luque, Irene

“…YAP is a WW domain-containing effector of the Hippo tumor suppressor pathway, and the object of heightened interest as a potent oncogene and stemness factor…”
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Interaction between tacrolimus, MELD score and acute kidney injury after liver transplantation. Analysis on a large contemporary bicenter meld‐era series by Ciria, Rubén, Gómez‐Luque, Irene, Cortés, Miriam, Khorsandi, Shirin E., Ayllón, Maria D., Rodríguez‐Perálvarez, Manuel, López‐Cillero, Pedro, De La Mata, Manuel, O'Grady, John, Heaton, Nigel, Briceño, Javier

“…Background Acute kidney injury (AKI) after liver transplantation (LT) is a common problem with complex management. The aims were to analyze the profile of…”
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Corrigendum to “Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway” [Biomed. Pharmacother. 175 (2024) 116785] by Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo

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New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells by Alburquerque-González, Begoña, Bernabé-García, Manuel, Montoro-García, Silvia, Bernabé-García, Ángel, Rodrigues, Priscila Campioni, Ruiz Sanz, Javier, López-Calderón, Fernando F., Luque, Irene, Nicolas, Francisco José, Cayuela, María Luisa, Salo, Tuula, Pérez-Sánchez, Horacio, Conesa-Zamora, Pablo

“…Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to…”
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Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway by Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo

“…Rearrangement of the actin cytoskeleton is a prerequisite for carcinoma cells to develop cellular protrusions, which are required for migration, invasion, and…”
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A Systematic Review and Meta-Analysis Comparing the Short- and Long-Term Outcomes for Laparoscopic and Open Liver Resections for Hepatocellular Carcinoma: Updated Results from the European Guidelines Meeting on Laparoscopic Liver Surgery, Southampton, UK, 2017 by Ciria, Ruben, Gomez-Luque, Irene, Ocaña, Sira, Cipriani, Federica, Halls, Mark, Briceño, Javier, Okuda, Yukihiro, Troisi, Roberto, Rotellar, Fernando, Soubrane, Olivier, Abu Hilal, Mohammed

“…Background The laparoscopic approach to liver resection has experienced exponential growth in recent years; however, its application is still under debate and…”
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Prototype Selection Method Based on the Rivality and Reliability Indexes for the Improvement of the Classification Models and External Predictions by Ruiz, Irene Luque, Gómez-Nieto, Miguel Ángel

“…Prototype or instance selection techniques is an important field of research in knowledge discovery, data mining, and machine learning. In QSAR, the use of…”
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Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition by Martin-Garcia, Jose M, Ruiz-Sanz, Javier, Luque, Irene

“…In spite of its biomedical relevance, polyproline recognition is still not fully understood. The disagreement between the current description of SH3 (Src…”
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Two-state dynamics of the SH3–SH2 tandem of Abl kinase and the allosteric role of the N-cap by Carles Corbi-Verge, Fabrizio Marinelli, Ana Zafra-Ruano, Javier Ruiz-Sanz, Irene Luque, José D. Faraldo-Gómez

“…The regulation and localization of signaling enzymes is often mediated by accessory modular domains, which frequently function in tandems. The ability of these…”
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Study of Data Set Modelability: Modelability, Rivality, and Weighted Modelability Indexes by Luque Ruiz, Irene, Gómez-Nieto, Miguel Ángel

“…The knowledge of the capacity of a data set to be modeled in the first stages of the building of quantitative structure–activity relationship (QSAR) prediction…”
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Effectiveness of an absorbable fibrin sealant patch to reduce lymphoceles formation after axillary lymphadenectomy for breast cancer: a matched-pair analysis by Navarro-Rodríguez, Elena, M.D, Gómez-Luque, Irene, M.D, Díaz-Jiménez, Nélida, M.D, Rioja-Torres, Pilar, M.D., Ph.D, Bascuñana-Estudillo, Guillermo, M.D, Ruiz-Rabelo, Juan Francisco, M.D., Ph.D, Ciria-Bru, Rubén, M.D., Ph.D, Álvarez-Benito, Marina, M.D., Ph.D, Rufián-Peña, Sebastián, M.D., Ph.D, Briceño-Delgado, Javier, M.D., Ph.D

“…Abstract Background This study evaluated the use of TachoSil as an adjunctive therapy for reducing axillary lymphocele formation. Methods Eighty-six patients…”
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Building of Robust and Interpretable QSAR Classification Models by Means of the Rivality Index by Luque Ruiz, Irene, Gómez-Nieto, Miguel Ángel

“…An unambiguous algorithm, added to the study of the applicability domain and appropriate measures of the goodness of fit and robustness, represent the key…”
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A systematic review and meta-analysis comparing the short- and long-term outcomes for laparoscopic and open liver resections for liver metastases from colorectal cancer by Ciria, Ruben, Ocaña, Sira, Gomez-Luque, Irene, Cipriani, Federica, Halls, Mark, Fretland, Åsmund Avdem, Okuda, Yukihiro, Aroori, Somaiah, Briceño, Javier, Aldrighetti, Luca, Edwin, Bjorn, Hilal, Mohammed Abu

“…Background The laparoscopic approach to liver resection has experienced exponential growth in recent years. However, evidence-based guidelines are needed for…”
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Structural parameterization of the binding enthalpy of small ligands by Luque, Irene, Freire, Ernesto

“…A major goal in ligand and drug design is the optimization of the binding affinity of selected lead molecules. However, the binding affinity is defined by the…”
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