Search Results - "Lupu, Loredana"
-
1
Michael Przybylski (1948–2023) Devoted Half a Century to Mass Spectrometry
Published in Journal of the American Society for Mass Spectrometry (06-09-2023)“…Michael Przybylski (1948–2023) was a Polymer Chemist by training and devoted nearly his entire scientific life, almost 50 years, to mass spectrometry and its…”
Get full text
Journal Article -
2
Identification and Affinity Determination of Protein-Antibody and Protein-Aptamer Epitopes by Biosensor-Mass Spectrometry Combination
Published in International journal of molecular sciences (27-11-2021)“…Analytical methods for molecular characterization of diagnostic or therapeutic targets have recently gained high interest. This review summarizes the…”
Get full text
Journal Article -
3
Antibody Epitope and Affinity Determination of the Myocardial Infarction Marker Myoglobin by SPR-Biosensor Mass Spectrometry
Published in Journal of the American Society for Mass Spectrometry (06-01-2021)“…Myoglobin (MG) is a biomarker for heart muscle injury, making it a potential target protein for early detection of myocardial infarction. Elevated myoglobin…”
Get full text
Journal Article -
4
Unveiling the molecular mechanisms underpinning biorecognition of early-glycated human serum albumin and receptor for advanced glycation end products
Published in Analytical and bioanalytical chemistry (01-07-2020)“…Serum levels of early-glycated albumin are significantly increased in patients with diabetes mellitus and may play a role in worsening inflammatory status and…”
Get full text
Journal Article -
5
Epitope characterization of proteins and aptamers with mass spectrometry
Published in European journal of mass spectrometry (Chichester, England) (01-12-2023)“…The way in which professor Michael Przybylski has combined the spirit of research with entrepreneurship has set an example for any and all scientists. He has…”
Get full text
Journal Article -
6
Epitope Identification and Affinity Determination of an Inhibiting Human Antibody to Interleukin IL8 (CXCL8) by SPR- Biosensor–Mass Spectrometry Combination
Published in Journal of the American Society for Mass Spectrometry (02-01-2020)“…The polypeptide chemokine Interleukin-8 (IL8) plays a crucial role in inflammatory processes in humans. IL8 is involved in chronic inflammatory lung diseases,…”
Get full text
Journal Article -
7
Epitope Ligand Binding Sites of Blood Group Oligosaccharides in Lectins Revealed by Pressure-Assisted Proteolytic Excision Affinity Mass Spectrometry
Published in Journal of the American Society for Mass Spectrometry (01-09-2018)“…Affinity mass spectrometry using selective proteolytic excision and extraction combined with MALDI and ESI mass spectrometry has been applied to the…”
Get full text
Journal Article -
8
Epitope and affinity determination of recombinant Mycobacterium tuberculosis Ag85B antigen towards anti-Ag85 antibodies using proteolytic affinity-mass spectrometry and biosensor analysis
Published in Analytical and bioanalytical chemistry (01-01-2019)“…Tuberculosis (TB) is the first cause of death from infectious diseases worldwide. Only a single anti-TB vaccine is currently available for clinical use, but…”
Get full text
Journal Article -
9
Molecular characterization of the [beta]-amyloid(4-10) epitope of plaque specific A[beta] antibodies by affinity-mass spectrometry using alanine site mutation
Published in Journal of peptide science (01-01-2018)“…Alzheimer disease is a neurodegenerative disease affecting an increasing number of patients worldwide. Current therapeutic strategies are directed to molecules…”
Get full text
Journal Article -
10
Molecular characterization of the β‐amyloid(4‐10) epitope of plaque specific Aβ antibodies by affinity‐mass spectrometry using alanine site mutation
Published in Journal of peptide science (01-01-2018)“…Alzheimer disease is a neurodegenerative disease affecting an increasing number of patients worldwide. Current therapeutic strategies are directed to molecules…”
Get full text
Journal Article -
11
Molecular Epitope Determination of Aptamer Complexes of the Multidomain Protein C‐Met by Proteolytic Affinity‐Mass Spectrometry
Published in ChemMedChem (17-02-2020)“…C‐Met protein is a glycosylated receptor tyrosine kinase of the hepatocyte growth factor (HGF), composed of an α and a β chain. Upon ligand binding, C‐Met…”
Get full text
Journal Article -
12
Front Cover: Molecular Epitope Determination of Aptamer Complexes of the Multidomain Protein C‐Met by Proteolytic Affinity‐Mass Spectrometry (ChemMedChem 4/2020)
Published in ChemMedChem (17-02-2020)“…The Front Cover shows the interaction epitopes of the extracellular structure of human C‐Met receptor protein complexes with two DNA‐aptamers of 60 and 64…”
Get full text
Journal Article -
13
Antibody Epitope of Human α‐Galactosidase A Revealed by Affinity Mass Spectrometry: A Basis for Reversing Immunoreactivity in Enzyme Replacement Therapy of Fabry Disease
Published in ChemMedChem (08-05-2018)“…α‐Galactosidase (αGal) is a lysosomal enzyme that hydrolyses the terminal α‐galactosyl moiety from glycosphingolipids. Mutations in the encoding genes for αGal…”
Get full text
Journal Article -
14
Investigation of Tumor Differentiation Factor (TDF)‐induced Cell Differentiation using Mass Spectrometry
Published in The FASEB journal (01-04-2015)“…Abstract only Tumor differentiation factor is a protein, produced by the pituitary gland and is secreted into the bloodstream. TDF is known to induce…”
Get full text
Journal Article -
15
Rational Design, Synthesis, and Characterization of Glycoconjugates as Potential Vaccines against Tuberculosis
Published in Proceedings (01-08-2019)“…Tuberculosis (TB) is the first cause of death from infectious diseases. [...]…”
Get full text
Journal Article -
16
Application layer protocol for IoT using wireless sensor networks communication protocols
Published in 2017 9th International Congress on Ultra Modern Telecommunications and Control Systems and Workshops (ICUMT) (01-11-2017)“…This paper aims at providing a communication architecture in order to enable the integration of traditional Wireless Sensor Networks into the Internet of…”
Get full text
Conference Proceeding