Electrophilic substitution as a convenient approach to functionalized N-benzyl-1,4-dihydropyridines

The reactivity of 1-benzyl-3-cyano-1,4-dihydropyridine was studied in reactions with electrophilic reagents based on structural analogy of 1,4-dihydropyridines with enamines. Different 5-functionalized derivatives were obtained by direct electrophilic substitution. Graphic

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Bibliographic Details
Published in:Tetrahedron letters Vol. 43; no. 31; pp. 5423 - 5425
Main Authors: Kostyuk, Aleksandr N, Volochnyuk, Dmitriy M, Lupihal, Larisa N, Pinchuk, Aleksandr M, Tolmachev, Andrei A
Format: Journal Article
Language:English
Published: Elsevier Ltd 29-07-2002
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Summary:The reactivity of 1-benzyl-3-cyano-1,4-dihydropyridine was studied in reactions with electrophilic reagents based on structural analogy of 1,4-dihydropyridines with enamines. Different 5-functionalized derivatives were obtained by direct electrophilic substitution. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(02)01083-3