Search Results - "Lupar, Ekaterina"
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Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function
Published in Proceedings of the National Academy of Sciences - PNAS (09-10-2018)“…Plasma cell differentiation involves coordinated changes in gene expression and functional properties of B cells. Here, we study the role of Mzb1, a Grp94…”
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EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential
Published in Nature immunology (01-03-2020)“…Crosstalk between mesenchymal stromal cells (MSCs) and hematopoietic stem cells (HSCs) is essential for hematopoietic homeostasis and lineage output. Here, we…”
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EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia
Published in Leukemia (01-08-2021)“…The transcription factor eomesodermin (EOMES) promotes interleukin (IL)-10 expression in CD4 + T cells, which has been linked to immunosuppressive and…”
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EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4.sup.+ T cells in chronic lymphocytic leukemia
Published in Leukemia (01-08-2021)“…The transcription factor eomesodermin (EOMES) promotes interleukin (IL)-10 expression in CD4.sup.+ T cells, which has been linked to immunosuppressive and…”
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Eomes and IL-10 Regulate Anti-Tumor Activity of T Cells in Chronic Lymphocytic Leukemia
Published in Blood (13-11-2019)“…Introduction: Genome-wide association studies showed that a single-nucleotide polymorphism (SNP) affecting the transcription factor Eomesodermin (Eomes) is…”
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Eomesodermin Expression in CD4+ T Cells Restricts Peripheral Foxp3 Induction
Published in The Journal of immunology (1950) (15-11-2015)“…CD4(+) T cells polarize into effector Th subsets characterized by signature transcription factors and cytokines. Although T-bet drives Th1 responses and…”
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Id3 Maintains Foxp3 Expression in Regulatory T Cells by Controlling a Transcriptional Network of E47, Spi-B, and SOCS3
Published in Cell reports (Cambridge) (13-12-2016)“…The transcription factor Foxp3 dominantly controls regulatory T (Treg) cell function, and only its continuous expression guarantees the maintenance of full…”
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Id3 Maintains Foxp3 Expression in Regulatory T Cells by Controlling a TranscriptionalNetwork of E47, Spi-B, and SOCS3
Published in Cell reports (Cambridge) (2016)“…The transcription factor Foxp3 dominantly controls regulatory T (Treg) cell function, and only its continuous expression guarantees the maintenance of full…”
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Journal Article