Search Results - "Luo, Yuewen"
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TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb
Published in eLife (17-01-2019)“…Comprehensively elucidating the molecular mechanisms of human immunodeficiency virus type 1 (HIV-1) latency is a priority to achieve a functional cure. As…”
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Two waves of pro-inflammatory factors are released during the influenza A virus (IAV)-driven pulmonary immunopathogenesis
Published in PLoS pathogens (01-02-2020)“…Influenza A virus (IAV) infection is a complicated process. After IAVs spread to the lung, extensive pro-inflammatory cytokines and chemokines are released,…”
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Improvement of a SARS-CoV-2 vaccine by enhancing the conjugation efficiency of the immunogen to self-assembled nanoparticles
Published in Cellular & molecular immunology (01-08-2021)Get full text
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Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors
Published in mBio (19-01-2021)“…The etiologic agent of COVID-19 is highly contagious and has caused a severe global pandemic. Until now, there has been no simple and reliable system available…”
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Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD
Published in European journal of medical research (03-07-2023)“…Chronic obstructive pulmonary disease (COPD) is a serious chronic lung disease. Schisandrin A (SchA) is one of the most important active ingredients in…”
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USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID
Published in Signal transduction and targeted therapy (04-01-2022)“…Activation-induced cytidine deaminase (AID) initiates class-switch recombination and somatic hypermutation (SHM) in antibody genes. Protein expression and…”
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USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
Published in eLife (09-08-2019)“…The antiviral activity of host factor apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G (APOBEC3G, A3G) and its degradation mediated by human…”
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Generation of a new therapeutic d-peptide that induces the differentiation of acute myeloid leukemia cells through A TLR-2 signaling pathway
Published in Cell death discovery (26-01-2024)“…Acute myeloid leukemia (AML) is caused by clonal disorders of hematopoietic stem cells. Differentiation therapy is emerging as an important treatment modality…”
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Deletion of a hybrid NRPS‐T1PKS biosynthetic gene cluster via Latour gene knockout system in Saccharopolyspora pogona and its effect on butenyl‐spinosyn biosynthesis and growth development
Published in Microbial biotechnology (01-11-2021)“…Using the Latour system, a hybrid NRPS‐T1PKS cluster (˜20 kb) which was responsible for phthoxazolin biosynthesis was efficiently deleted in S. pogona. A TetR…”
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Comparative Proteomics Reveals the Effect of the Transcriptional Regulator Sp13016 on Butenyl-Spinosyn Biosynthesis in Saccharopolysp ora pogona
Published in Journal of agricultural and food chemistry (27-10-2021)“…Butenyl-spinosyn is a highly effective and broad-spectrum biopesticide produced by Saccharopolyspora pogona. However, the yield of this compound is difficult…”
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RNA-Seq-Based Transcriptomic Analysis of Saccharopolyspora spinosa Revealed the Critical Function of PEP Phosphonomutase in the Replenishment Pathway
Published in Journal of agricultural and food chemistry (09-12-2020)“…Spinosyns, the secondary metabolites produced by Saccharopolyspora spinosa, are the active ingredients in a family of novel biological insecticides. Although…”
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Counting Permutations in $S_{2n}$ and $S_{2n+1}
Published 10-07-2024“…Let $\alpha(n)$ denote the number of perfect square permutations in the symmetric group $S_n$. The conjecture $\alpha(2n+1) = (2n+1) \alpha(2n)$, provided by…”
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CRL2KLHDC3 mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression
Published in Oncogene (27-05-2022)“…Kelch superfamily involves a variety of proteins containing multiple kelch motif and is well characterized as substrate adaptors for CUL3 E3 ligases, which…”
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Quanzhen Yiqi decoction attenuates inflammation in mice with smoking-induced COPD by activating the Nrf2/HO-1 pathway and inhibiting the NLRP3 inflammasome
Published in Journal of pharmacy and pharmacology (26-04-2024)“…Quanzhen Yiqi decoction (QZYQ) is a traditional Chinese medicine for treating chronic obstructive pulmonary disease. Mice were exposed to cigarette smoke (CS)…”
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CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes
Published in The Journal of immunology (1950) (01-07-2019)“…Activation-induced cytidine deaminase (AID) initiates class switch recombination and somatic hypermutation in Ig genes. The activity and protein levels of AID…”
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Two waves of pro-inflammatory factors are released during the influenza A virus
Published in PLoS pathogens (26-02-2020)Get full text
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CRL2 KLHDC3 mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression
Published in Oncogene (01-05-2022)“…Kelch superfamily involves a variety of proteins containing multiple kelch motif and is well characterized as substrate adaptors for CUL3 E3 ligases, which…”
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VibraForge: A Scalable Prototyping Toolkit For Creating Spatialized Vibrotactile Feedback Systems
Published 25-09-2024“…Spatialized vibrotactile feedback systems deliver tactile information by placing multiple vibrotactile actuators on the body. As increasing numbers of…”
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