Search Results - "Luo, QingYu"

Ubiquitination and deubiquitination of MCL1 in cancer: deciphering chemoresistance mechanisms and providing potential therapeutic options by Wu, Xiaowei, Luo, Qingyu, Liu, Zhihua

“…MCL1 is an important antiapoptotic member of the BCL-2 family that is distinguishable from other family members based on its relatively short half-life…”
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JOSD1 inhibits mitochondrial apoptotic signalling to drive acquired chemoresistance in gynaecological cancer by stabilizing MCL1 by Wu, Xiaowei, Luo, Qingyu, Zhao, Pengfei, Chang, Wan, Wang, Yating, Shu, Tong, Ding, Fang, Li, Bin, Liu, Zhihua

“…Gynaecological cancer is a main subtype of cancer in women, and acquired chemoresistance is a major contributor to the poor prognosis of gynaecological cancer,…”
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Identification of critical links in a large-scale road network considering the traffic flow betweenness index by Li, Feiyan, Jia, Hongfei, Luo, Qingyu, Li, Yongxing, Yang, Lili

“…The traditional full-scan method is commonly used for identifying critical links in road networks. This method simulates each link to be closed iteratively and…”
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MGMT-activated DUB3 stabilizes MCL1 and drives chemoresistance in ovarian cancer by Wu, Xiaowei, Luo, Qingyu, Zhao, Pengfei, Chang, Wan, Wang, Yating, Shu, Tong, Ding, Fang, Li, Bin, Liu, Zhihua

“…Chemoresistance is a severe outcome among patients with ovarian cancer that leads to a poor prognosis. MCL1 is an antiapoptotic member of the BCL-2 family that…”
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ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c-Myc-mediated cancer stemness by Luo, Qingyu, Wu, Xiaowei, Chang, Wan, Zhao, Pengfei, Nan, Yabing, Zhu, Xiaolin, Katz, Jonathan P., Su, Dan, Liu, Zhihua

“…Squamous cell carcinoma (SCC) is defined as a category of aggressive malignancies arising from the squamous epithelium of various organs. Resistance to…”
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Multi-objective optimization of urban road intersection signal timing based on particle swarm optimization algorithm by Jia, Hongfei, Lin, Yu, Luo, Qingyu, Li, Yongxing, Miao, Hongzhi

“…Currently, signal control mode is the main control method of urban road intersections. Given that the traffic efficiency of road intersections is mainly…”
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Downregulation of the GLP-1/CREB/adiponectin pathway is partially responsible for diabetes-induced dysregulated vascular tone and VSMC dysfunction by Xiong, Xiaowei, Lu, Weihang, Qin, Xuan, Luo, Qingyu, Zhou, Weimin

“…[Display omitted] •Increased vascular tones were observed in both diabetic patients and animals.•GLP-1 supplementation improved the mitochondrial functions and…”
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TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma by Luo, Qingyu, Wu, Xiaowei, Nan, Yabing, Chang, Wan, Zhao, Pengfei, Zhang, Yiping, Su, Dan, Liu, Zhihua

“…Squamous cell carcinoma (SCC) is an aggressive epithelial malignancy, yet the molecular mechanisms underlying SCC development are elusive. ARID1A is frequently…”
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OTUD1 Activates Caspase‐Independent and Caspase‐Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation by Luo, Qingyu, Wu, Xiaowei, Zhao, Pengfei, Nan, Yabing, Chang, Wan, Zhu, Xiaolin, Su, Dan, Liu, Zhihua

“…Apoptosis‐inducing factor (AIF) plays a dual role in regulating cell survival and apoptosis, acting as a prosurvival factor in mitochondria via its NADH…”
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ARID1A Hypermethylation Disrupts Transcriptional Homeostasis to Promote Squamous Cell Carcinoma Progression by Luo, Qingyu, Wu, Xiaowei, Chang, Wan, Zhao, Pengfei, Zhu, Xiaolin, Chen, Hongyan, Nan, Yabing, Luo, Aiping, Zhou, Xuantong, Su, Dan, Jiao, Wenjie, Liu, Zhihua

“…Switch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complexes have a mutation rate of approximately 20% in human cancer, and is the most frequently…”
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m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation by Nan, Yabing, Liu, Shi, Luo, Qingyu, Wu, Xiaowei, Zhao, Pengfei, Chang, Wan, Zhang, Ruixiang, Li, Yin, Liu, Zhihua

“…RNA N6-methyladenosine (m6A) modification is implicated in cancer progression, yet its role in regulating long noncoding RNAs during cancer progression remains…”
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The deubiquitinase USP11 promotes ovarian cancer chemoresistance by stabilizing BIP by Zhu, Xiaolin, Zhang, Yiping, Luo, Qingyu, Wu, Xiaowei, Huang, Furong, Shu, Tong, Wan, Yong, Chen, Hongyan, Liu, Zhihua

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A two-stage layout method for functional areas in logistics park by Luo, Qingyu, Zhu, Jiaxiang, Jia, Hongfei, Xu, Yingjun

“…The layout of functional areas has a great impact on the implementing of a logistics park. Existing layout models with multiple planning objectives and…”
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Dynamic Cascading Failure Analysis in Congested Urban Road Networks With Self-Organization by Jia, Hongfei, Li, Feiyan, Yang, Lili, Luo, Qingyu, Li, Yongxing

“…An efficient freight transportation system is a core part of the modern urban logistics. The transportation system depends on an efficient urban road network…”
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Dynamic Path Planning for Autonomous Driving on Branch Streets With Crossing Pedestrian Avoidance Guidance by Wu, Wenjing, Jia, Hongfei, Luo, Qingyu, Wang, Zhanzhong

“…This paper presents a real-time dynamic path planning method for autonomous driving to avoid collision with crossing pedestrian on branch streets. The velocity…”
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Inhibition of XIAP increases carboplatin sensitivity in ovarian cancer by Zhang, Yiping, Huang, Furong, Luo, Qingyu, Wu, Xiaowei, Liu, Zhihua, Chen, Hongyan, Huang, Yinghui

“…Carboplatin is a first-line treatment for ovarian cancer. However, most patients develop resistance and undergo disease recurrence. This study aims to explore…”
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Game Theory Modelling for Vehicle U-Turn Behavior and Simulation Based on Cellular Automata by Ma, Fangwu, Luo, QingYu, Liang, ZhiKang, Wu, WenJing

“…In order to analyze the effect of U-turn vehicle on traffic performance, the work develops a game theory-based description of drivers’ interactions in U-turn…”
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Facile Synthesis of Quaternary Structurally Ordered L12‑Pt(Fe, Co, Ni)3 Nanoparticles with Low Content of Platinum as Efficient Oxygen Reduction Reaction Electrocatalysts by Wang, Sihao, Luo, Qingyu, Zhu, Yingfang, Tang, Shaolong, Du, Youwei

“…Synthesis of electrocatalysts for oxygen reduction reaction (ORR) with not only prominent electrocatalytic performance but also a low amount of Pt is the…”
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The clinical efficacy of collagen dressing on chronic wounds: A meta-analysis of 11 randomized controlled trials by Shu, Hongxin, Xia, Zhiyu, Qin, Xuan, Wang, Xiaowei, Lu, Weihang, Luo, Qingyu, Zhang, Zhenxiong, Xiong, Xiaowei

“…ObjectiveThis study aims to evaluate the clinical efficacy of collagen dressing for patients with chronic wounds. Materials and methodsRelevant randomized…”
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Fabricating high-loading ultra-small PtCu3/rGO via a traceless protectant and spray-freeze-drying method by Luo, Qingyu, Xu, Wei, Tang, Shaolong

“…Exploring excellent catalysts for oxygen reduction reaction (ORR) with a facile and cost-effective method is desirable but remains challenging. Herein,…”
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