Search Results - "Luo, Michelle L"

Current and future prospects for CRISPR-based tools in bacteria by Luo, Michelle L., Leenay, Ryan T., Beisel, Chase L.

“…ABSTRACT CRISPR‐Cas systems have rapidly transitioned from intriguing prokaryotic defense systems to powerful and versatile biomolecular tools. This article…”
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Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System by Marshall, Ryan, Maxwell, Colin S., Collins, Scott P., Jacobsen, Thomas, Luo, Michelle L., Begemann, Matthew B., Gray, Benjamin N., January, Emma, Singer, Anna, He, Yonghua, Beisel, Chase L., Noireaux, Vincent

“…CRISPR-Cas systems offer versatile technologies for genome engineering, yet their implementation has been outpaced by ongoing discoveries of new Cas nucleases…”
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Programmable removal of bacterial strains by use of genome-targeting CRISPR-Cas systems by Gomaa, Ahmed A, Klumpe, Heidi E, Luo, Michelle L, Selle, Kurt, Barrangou, Rodolphe, Beisel, Chase L

“…CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems in bacteria and archaea employ CRISPR RNAs to specifically…”
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Impact of Residual Inducer on Titratable Expression Systems by Afroz, Taliman, Luo, Michelle L, Beisel, Chase L

“…Inducible expression systems are widely employed for the titratable control of gene expression, yet molecules inadvertently present in the growth medium or…”
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Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression by Luo, Michelle L, Mullis, Adam S, Leenay, Ryan T, Beisel, Chase L

“…CRISPR-Cas systems have shown tremendous promise as heterologous tools for genome editing and transcriptional regulation. Because these RNA-directed immune…”
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The CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacers by Luo, Michelle L, Jackson, Ryan N, Denny, Steven R, Tokmina-Lukaszewska, Monika, Maksimchuk, Kenneth R, Lin, Wayne, Bothner, Brian, Wiedenheft, Blake, Beisel, Chase L

“…Bacteria and archaea acquire resistance to foreign genetic elements by integrating fragments of foreign DNA into CRISPR (clustered regularly interspaced short…”
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Engineering Genes with CRISPR-Cas9 by Luo, Michelle L, Beisel, Chase L

“…While parties are warring over CRISPR-Cas9 patents, other CRISPR discoveries and innovations have continued to surface. Recently, a new Cas protein called Cpfl…”
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