Search Results - "Luo, Li Z."

HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation by Chia, Lionel, Wang, Bowen, Kim, Jung-Hyun, Luo, Li Z, Shuai, Shuai, Herrera, Iliana, Chen, Sophia Y, Li, Liping, Xian, Lingling, Huso, Tait, Heydarian, Mohammad, Reddy, Karen, Sung, Woo Jung, Ishiyama, Shun, Guo, Gongbo, Jaffee, Elizabeth, Zheng, Lei, Cope, Leslie M, Gabrielson, Kathy, Wood, Laura, Resar, Linda

“…High mobility group A1 (HMGA1) chromatin regulators are upregulated in diverse tumors where they portend adverse outcomes, although how they function in cancer…”
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HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression by Li, Liping, Kim, Jung-Hyun, Lu, Wenyan, Williams, Donna M., Kim, Joseph, Cope, Leslie, Rampal, Raajit K., Koche, Richard P., Xian, Lingling, Luo, Li Z., Vasiljevic, Marija, Matson, Daniel R., Zhao, Zhizhuang Joe, Rogers, Ophelia, Stubbs, Matthew C., Reddy, Karen, Romero, Antonio-Rodriguez, Psaila, Bethan, Spivak, Jerry L., Moliterno, Alison R., Resar, Linda M.S.

“…Myeloproliferative neoplasms (MPNs) transform to myelofibrosis (MF) and highly lethal acute myeloid leukemia (AML), although the actionable mechanisms driving…”
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DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells by Luo, Li Z, Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L, Park, Sang-Won, Bates, Steven E, Zeng, Xianmin, Iverson, Linda E, O'Connor, Timothy R

“…The potential for human disease treatment using human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), also…”
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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Luo, Li Z., Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L., Park, Sang-Won, Bates, Steven E., Zeng, Xianmin, Iverson, Linda E., O'Connor, Timothy R.

“…The author's affiliation is 2 Department of Stem Cell Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United…”
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The High Mobility Group A1 ( HMGA1 ) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 ( MMP-2 ) in a subset of tumors by Hillion, Joelle, Roy, Sujayita, Heydarian, Mohammad, Cope, Leslie, Xian, Lingling, Koo, Michael, Luo, Li Z, Kellyn, Kathleen, Ronnett, Brigitte M, Huso, Tait, Armstrong, Deborah, Reddy, Karen, Huso, David L, Resar, L.M.S

“…Abstract Objectives Although uterine cancer is the fourth most common cause for cancer death in women worldwide, the molecular underpinnings of tumor…”
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Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures by Lourdusamy, Anbarasu, Luo, Li Z, Storer, Lisa Cd, Cohen, Kenneth J, Resar, Linda, Grundy, Richard G

“…Pediatric spinal ependymomas (SEPN) are important albeit uncommon malignant central nervous system tumors with limited treatment options. Our current knowledge…”
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STAT3 inhibitor has potent antitumor activity in B-lineage acute lymphoblastic leukemia cells overexpressing the high mobility group A1 (HMGA1)-STAT3 pathway by Belton, Amy, Xian, Lingling, Huso, Tait, Koo, Michael, Luo, Li Z., Turkson, James, Page, Brent D. G., Gunning, Patrick T., Liu, Guosheng, Huso, David L., Resar, Linda M. S.

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Cigarette smoke induces anaphase bridges and genomic imbalances in normal cells by Luo, Li Z, Werner, Kristen M, Gollin, Susanne M, Saunders, William S

“…Exposure to cigarette smoke has long been linked to carcinogenesis, but the emphasis has been placed on mutational changes in the DNA sequence caused by the…”
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High Mobility Group A1 Chromatin Regulators Drive Regenerative Capacity during Stress Hematopoiesis through Modulation of TNF-α and Aging Transcriptional Networks by Thompson, Zanshe, Luo, Li Z, Wang, Bowen, Kim, Jung-Hyun, Woo, Hyunsung, Cope, Leslie, Resar, Linda

“…Introduction: Chromatin structure and epigenetic modifications are key determinants of regenerative function and cell fate decisions, although mechanisms…”
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Single Cell Transcriptomics Reveal That HMGA1 Chromatin Regulators Drive Transcriptional Networks Involved in Megakaryocyte Expansion, Platelet Activation, and Interferon Signaling in JAK2 V617F Myeloproliferative Neoplasms by Thompson, Zanshe, Luo, Li Z, Li, Liping, Wang, Bowen, Kim, Jung-Hyun, Woo, Hyunsung, West, Bailey, Krishnan, Anandi, Cope, Leslie, Moliterno, Alison R., Spivak, Jerry L., Resar, Linda

“…Introduction: Myeloproliferative neoplasms (MPN) are clonal hematopoietic stem cell (HSC) disorders characterized by hyperactive JAK/STAT signaling,…”
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A c- MPL Splice Variant up-Regulated in Myeloproliferative Neoplasms Modulates Thrombopoietin Signaling and Induces Cycling of Hematopoietic Stem Cells and Inflammatory Progenitors by Resar, Linda, Thompson, Zanshe, Luo, Li Z, Williams, Donna Marie, Li, Liping, Cope, Leslie, Herrera, Iliana, Rogers, Ophelia, Moliterno, Alison R., Spivak, Jerry L.

“…Introduction: Myeloproliferative neoplasms (MPN) are clonal disorders caused by mutations that activate JAK/STAT signaling through the thrombopoietin receptor,…”
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Abstract 1259: HMGA1: An epigenetic gatekeeper of Wnt signals during colon tumorigenesis and regeneration by Resar, Linda M. S., Luo, Li Z., Xian, Lingling, Herrera, Iliana, Wu, Shaoguang, Kim, Jung-Hyun, Feng, Ying, Calderon-Espinosa, Julian, Fearon, Eric R., Sears, Cynthia

“…Abstract Cancer cells undergo epigenetic reprogramming to co-opt stem cell networks and drive tumor progression, although how this occurs remains unclear. The…”
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Abstract LB-224: A novel model of pediatric spinal ependymoma using conditionally reprogrammed cells from a primary tumor demonstrates aberrant expression of HMGA, HOX, MYC and other Wnt target genes by Luo, Li Z., Krawczyk, Ewa, Lourdusamy, Anbarasu, Storer, Lisa C., Xian, Lingling, Cohen, Kenneth J., Schlegel, Richard, Grundy, Richard, Resar, Linda

“…Abstract Pediatric spinal ependymomas are rare tumors of the central nervous system with limited treatment options. Successful outcomes depend primarily upon…”
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Abstract 5592: HMGA1 modulates chromatin state and transcriptional networks involved in plasticity in refractory myeloid leukemia by West, Bailey E., Kim, Jung-Hyun, Supreme, Audrey-Ann, Herrera, Iliana, Thompson, Zanshé, Luo, Li Z., Shaik, Faiza, Kim, Joseph, Woo, Hyunsung, Meshinchi, Soheil, Ries, Rhonda E., Resar, Linda M.

“…Abstract Although High Mobility Group A1 (HMGA1) chromatin regulators are overexpressed in refractory acute myeloid leukemia (AML) and diverse solid tumors,…”
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The High Mobility Group A1 (HMGA1) Gene is Highly Overexpressed in Human Uterine Serous Carcinomas and Carsinosarcomas and Drives Matrix Metalloproteinase-2 (MMP-2) in a Subset of Tumors by Hillion, Joelle, Roy, Sujayita, Heydarian, Mohammad, Cope, Leslie, Xian, Lingling, Koo, Michael, Luo, Li Z., Kellyn, Kathleen, Ronnett, Brigitte M., Huso, Tait, Armstrong, Deborah, Reddy, Karen, Huso, David L., Resar, L. M. S.

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Deficiency in myosin light-chain phosphorylation causes cytokinesis failure and multipolarity in cancer cells by Wu, Q, Sahasrabudhe, R M, Luo, L Z, Lewis, D W, Gollin, S M, Saunders, W S

“…Cancer cells often have unstable genomes and increased centrosome and chromosome numbers, which are an important part of malignant transformation in the most…”
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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Luo, Li Z., Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L., Park, Sang-Won, Bates, Steven E., Zeng, Xianmin, Iverson, Linda E., O'Connor, Timothy R.

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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Luo, Li Z., Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L., Park, Sang-Won, Bates, Steven E., Zeng, Xianmin, Iverson, Linda E., O'Connor, Timothy R.

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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Li Z. Luo, Sailesh Gopalakrishna-Pillai, Stephanie L. Nay, Sang-Won Park, Steven E. Bates, Xianmin Zeng, Linda E. Iverson, Timothy R. O'Connor

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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Li Z. Luo, Sailesh Gopalakrishna-Pillai, Stephanie L. Nay, Sang-Won Park, Steven E. Bates, Xianmin Zeng, Linda E. Iverson, Timothy R. O'Connor

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