Search Results - "Luo, JinLi"

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts by Shaw, Jacqueline A, Guttery, David S, Hills, Allison, Fernandez-Garcia, Daniel, Page, Karen, Rosales, Brenda M, Goddard, Kate S, Hastings, Robert K, Luo, Jinli, Ogle, Olivia, Woodley, Laura, Ali, Simak, Stebbing, Justin, Coombes, R Charles

“…The purpose of this study was to directly compare mutation profiles in multiple single circulating tumor cells (CTC) and cell-free DNA (cfDNA) isolated from…”
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Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer by Guttery, David S, Page, Karen, Hills, Allison, Woodley, Laura, Marchese, Stephanie D, Rghebi, Basma, Hastings, Robert K, Luo, Jinli, Pringle, J Howard, Stebbing, Justin, Coombes, R Charles, Ali, Simak, Shaw, Jacqueline A

“…Activating mutations in the estrogen receptor 1 (ESR1) gene are acquired on treatment and can drive resistance to endocrine therapy. Because of the spatial and…”
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Molecular mechanisms, targets and clinical potential of berberine in regulating metabolism: a review focussing on databases and molecular docking studies by Sun, Aru, Yang, Haoyu, Li, Tao, Luo, Jinli, Zhou, Ling, Chen, Rui, Han, Lin, Lin, Yiqun

“…Metabolic imbalance is the common basis of many diseases. As natural isoquinoline alkaloid, berberine (BBR) has shown great promise in regulating glucose and…”
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Jiedutongluotiaogan formula restores pancreatic function by suppressing excessive autophagy and endoplasmic reticulum stress by Luo, Jinli, Jin, Wenqi, Jin, Meiying, Pan, Weiwei, Gao, Shengnan, Zhao, Xiaohua, Lai, Xingrong, Sun, Liwei, Piao, Chunli

“…Jiedutongluotiaogan formula (JTTF), a traditional Chinese medicine (TCM), could promote islet function. However, the potential effect of JTTF on endoplasmic…”
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Clinical comparative efficacy and therapeutic strategies for the Hashimoto's thyroiditis: A systematic review and network meta-analysis by Luo, Jinli, Zhou, Ling, Sun, Aru, Min, Ye, Lin, Yiqun, Han, Lin

“…Vitamin D (VD), selenium preparations (Se), and thyroid hormone replacement therapy are commonly used to treat Hashimoto thyroiditis (HT). Increasing evidence…”
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Identifying Biomarkers from Transcriptomic Signatures in Renal Allograft Biopsies Using Deceased and Living Donors by Yang, Bin, Sylvius, Nicolas, Luo, Jinli, Yang, Cheng, Da, Zhanyun, Crotty, Charlottelrm, Nicholson, Michael L.

“…The survival of transplant kidneys using deceased donors (DD) is inferior to living donors (LD). In this study, we conducted a whole-transcriptome expression…”
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Treatment of COVID-19 in Hemodialysis Patients Using Traditional Chinese Medicine: A Single-Center, Retrospective Study by Huang, Wei, Jiang, Bo, Luo, Jinli, Luo, Meng, Ding, Xiaoming, Yang, Qian, Zhao, Lin-Hua, Sun, Qin-Guo, Tong, Xiao-Lin

“…To explore the effect of combining traditional Chinese medicine (TCM) and Western medicine in hemodialysis patients with coronavirus disease 2019 (COVID-19)…”
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Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation by Pointon, Amy V, Walker, Tracy M, Phillips, Kate M, Luo, Jinli, Riley, Joan, Zhang, Shu-Dong, Parry, Joel D, Lyon, Jonathan J, Marczylo, Emma L, Gant, Timothy W

“…Doxorubicin is one of the most effective anti-cancer drugs but its use is limited by cumulative cardiotoxicity that restricts lifetime dose. Redox damage is…”
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Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK by Hey, Fiona, Andreadi, Catherine, Noble, Catherine, Patel, Bipin, Jin, Hong, Kamata, Tamihiro, Straatman, Kees, Luo, Jinli, Balmanno, Kathryn, Jones, David T.W., Collins, V. Peter, Cook, Simon J., Caunt, Christopher J., Pritchard, Catrin

“…BRAF is a cytoplasmic protein kinase, which activates the MEK-ERK signalling pathway. Deregulation of the pathway is associated with the presence of BRAF…”
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Essential Role of the AH Receptor in the Dysfunction of Heme Metabolism Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin by Davies, Reginald, Clothier, Bruce, Robinson, Susan W, Edwards, Richard E, Greaves, Peter, Luo, JinLi, Gant, Timothy W, Chernova, Tatyana, Smith, Andrew G

“…The dysfunction of hepatic heme synthesis by 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD) in mice, enhanced by iron, leads to accumulation of uroporphyrins I and…”
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Pharmacological effects of polydatin in the treatment of metabolic diseases: A review by Luo, Jinli, Chen, Shuo, Wang, Li, Zhao, Xiaohua, Piao, Chunli

“…Metabolic diseases (MDs), a series of chronic disorders, severely decreases the quality of life for patients but also cause a heavy economic burden. Emerging…”
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Characterization of Heparin Oligosaccharide Mixtures as Ammonium Salts Using Electrospray Mass Spectrometry by Chai, Wengang, Luo, Jinli, Lim, Chang Kee, Lawson, Alexander M

“…Among glycosaminoglycans, polysulfated heparin chains provide the greatest challenge to characterization due to high polarity, structural diversity, and…”
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Herbal medicine for Hashimoto's thyroiditis: A systematic review and network meta-analysis by Luo, Jinli, Zhou, Ling, Sun, Aru, Yang, Haoyu, Zhang, Pei, Liu, Ke, Yu, Xiaotong, Lin, Yiqun, Huang, Yishan, Han, Lin

“…Conventional treatments for Hashimoto's thyroiditis (HT) are limited. Herbal medicines (HM) are considered a potential intervention for the treatment of HT…”
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Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development by Kamata, Tamihiro, So, Tsz Y., Ahmed, Qasim, Giblett, Susan, Patel, Bipin, Luo, Jinli, Reddel, Roger, Pritchard, Catrin

“…The tumor microenvironment (TME) consists of different cell types, including tumor-associated macrophages (TAMs) and tumor-associated fibroblasts (TAFs). How…”
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Investigation of the mechanism of action of simiao pill against gout using network pharmacology and experimental validation by Luo, Jinli, Chen, Shuo, Zhang, Naiwen, Gao, Shengnan, Piao, Chunli

“…Gout is a chronic disease of deposition of monosodium urate crystals, characterised by hyperuricaemia and gouty arthritis, plaguing the whole world. Simiao…”
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Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism by Smith, A G, Clothier, B, Robinson, S, Scullion, M J, Carthew, P, Edwards, R, Luo, J, Lim, C K, Toledano, M

“…The binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with the aryl hydrocarbon (AH) receptor and subsequent changes in gene expression have been studied…”
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Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer by Page, Karen, Guttery, David S, Fernandez-Garcia, Daniel, Hills, Allison, Hastings, Robert K, Luo, Jinli, Goddard, Kate, Shahin, Vedia, Woodley-Barker, Laura, Rosales, Brenda M, Coombes, R Charles, Stebbing, Justin, Shaw, Jacqueline A

“…Breast cancer tissues are heterogeneous and show diverse somatic mutations and somatic copy number alterations (CNAs). We used a novel targeted next generation…”
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Mechanism of Rhubarb for Diabetic Kidney Disease through the AMPK/NF‐κB Signaling Pathway Based on Network Pharmacology by Luo, Jinli, Piao, Chunli, Jin, De, Wang, Li, Zhao, Xiaohua, Lian, Fengmei, Tong, Xiaolin

“…Rhubarb (Da‐huang in pinyin, Radix Rhei Et Rhizome in pharmaceutical name) is a heat‐clearing and laxative herbal medicine, which is widely used to treat…”
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Profiling tumour heterogeneity through circulating tumour DNA in patients with pancreatic cancer by Adamo, Patricia, Cowley, Caroline M, Neal, Christopher P, Mistry, Vilas, Page, Karen, Dennison, Ashley R, Isherwood, John, Hastings, Robert, Luo, JinLi, Moore, David A, Howard, Pringle J, Miguel, Martins L, Pritchard, Catrin, Manson, Margaret, Shaw, Jacqui A

“…The majority of pancreatic ductal adenocarcinomas (PDAC) are diagnosed late so that surgery is rarely curative. Earlier detection could significantly increase…”
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Study of temoporfin metabolism by HPLC and electrospray mass spectrometry by Cai, Hong, Wang, Qiang, Luo, Jinli, Lim, C. K.

“…The in vivo and in vitro metabolism of temoporfin (m‐THPC), one of the most potent photosensitizers for the treatment of cancer by photodynamic therapy, has…”
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