Search Results - "Luo, Hui Chen"

C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse by Yang, Li-Xue, Zhang, Cheng-Tao, Yang, Meng-Ying, Zhang, Xue-Hong, Liu, Hong-Chen, Luo, Chen-Hui, Jiang, Yue, Wang, Zhang-Man, Yang, Zhong-Yin, Shi, Zhao-Peng, Yang, Yi-Ci, Wei, Ruo-Qu, Zhou, Li, Mi, Jun, Zhou, Ai-Wu, Yao, Zhi-Rong, Xia, Li, Yan, Jin-Song, Lu, Ying

“…•C1Q+ cells represent a highly tissue-infiltrative leukemia population and could reconstitute EMI phenotype of AML.•Fibroblast attracts C1Q+ leukemia cell via…”
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Downregulation of RIF1 Enhances Sensitivity to Platinum-Based Chemotherapy in Epithelial Ovarian Cancer (EOC) by Regulating Nucleotide Excision Repair (NER) Pathway by Liu, Yong-Bin, Mei, Ying, Tian, Zheng-Wen, Long, Jing, Luo, Chen-Hui, Zhou, Hong-Hao

“…Background/Aims: Rap1 interacting factor 1 (RIF1) was deemed to be involved in replication timing regulation and DNA damage response. However, little is known…”
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Mitochondrial oxidative phosphorylation is dispensable for survival of CD34+ chronic myeloid leukemia stem and progenitor cells by Yan, Jin-Song, Yang, Meng-Ying, Zhang, Xue-Hong, Luo, Chen-Hui, Du, Cheng-Kan, Jiang, Yue, Dong, Xuan-Jia, Wang, Zhang-Man, Yang, Li-Xue, Li, Yi-Dong, Xia, Li, Lu, Ying

“…Chronic myeloid leukemia (CML) are initiated and sustained by self-renewing malignant CD34 + stem cells. Extensive efforts have been made to reveal the…”
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TRPM7 is required for ovarian cancer cell growth, migration and invasion by Wang, Jing, Liao, Qian-jin, Zhang, Yi, Zhou, Hui, Luo, Chen-hui, Tang, Jie, Wang, Ying, Tang, Yan, Zhao, Min, Zhao, Xue-heng, Zhang, Qiong-yu, Xiao, Ling

“…•Silence of TRPM7 in ovarian cancer cells inhibits cell proliferation, migration and invasion.•Silence of TRPM7 decreases phosphorylation levels of Akt, Src…”
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A two-stage genome-wide association study identifies novel germline genetic variations in CACNA2D3 associated with radiotherapy response in nasopharyngeal carcinoma by Yu, Lu-Lu, Hu, Bi-Wen, Huang, Han-Xue, Yu, Bing, Xiao, Qi, Lv, Qiao-Li, Luo, Chen-Hui, Guo, Cheng-Xian, Li, Jin-Gao, Xie, Xiao-Xue, Yin, Ji-Ye

“…Radiotherapy (RT) is the standard treatment for nasopharyngeal carcinoma (NPC). However, due to individual differences in radiosensitivity, biomarkers are…”
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Determinants of the over-anticoagulation response during warfarin initiation therapy in Asian patients based on population pharmacokinetic-pharmacodynamic analyses by Ohara, Minami, Takahashi, Harumi, Lee, Ming Ta Michael, Wen, Ming-Shien, Lee, Tsong-Hai, Chuang, Hui-Ping, Luo, Chen-Hui, Arima, Aki, Onozuka, Akiko, Nagai, Rui, Shiomi, Mari, Mihara, Kiyoshi, Morita, Takashi, Chen, Yuan-Tsong

“…To clarify pharmacokinetic-pharmacodynamic (PK-PD) factors associated with the over-anticoagulation response in Asians during warfarin induction therapy,…”
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Complex analysis of the personalized pharmacotherapy in the management of COVID-19 patients and suggestions for applications of predictive, preventive, and personalized medicine attitude by Wang, Lei-Yun, Cui, Jia-Jia, OuYang, Qian-Ying, Zhan, Yan, Wang, Yi-Min, Xu, Xiang-Yang, Yu, Lu-Lu, Yin, Hui, Wang, Yang, Luo, Chen-Hui, Guo, Cheng-Xian, Yin, Ji-Ye

“…Aims Coronavirus disease 2019 (COVID-19) is rapidly spreading worldwide. Drug therapy is one of the major treatments, but contradictory results of clinical…”
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Validation of a liquid chromatography-electrospray ionization-tandem mass spectrometry method for determination of all-trans retinoic acid in human plasma and its application to a bioequivalence study by Peng, Jing-Bo, Luo, Chen-Hui, Wang, Yi-Cheng, Huang, Wei-Hua, Chen, Yao, Zhou, Hong-Hao, Tan, Zhi-Rong

“…A sensitive, reliable and specific LC-MS-MS method was developed and validated for the identification and quantitation of all-trans retinoic acid (ATRA) in…”
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Effect of Probenecid on Pharmacokinetics and Tolerability of Olmesartan in Healthy Chinese Volunteers by Li, Kun-Yan, PhD, Qiu, Yu, MS, Jiang, Yun, BS, Luo, Chen-Hui, MS, Lin, Xiao-Ping, BS, Wang, Jing, BS, Yang, Nong, MS

“…Abstract Background Olmesartan is an angiotensin II receptor antagonist and is effective and well tolerated in the treatment of arterial hypertension…”
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Identification of SARS-CoV-2 m6A modification sites correlate with viral pathogenicity by Liu, Ke, Zhang, Ying-Zi, Yin, Hui, Yu, Lu-Lu, Cui, Jia-Jia, Yin, Ji-Ye, Luo, Chen-Hui, Guo, Cheng-Xian

“…It has recently been found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) m6A modifications can affect viral replication and function…”
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Ile118Val genetic polymorphism of CYP3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients by AN WANG, YU, Bang-Ning, LUO, Chen-Hui, TAN, Zhi-Rong, GAN ZHOU, WANG, Lian-Sheng, WEI ZHANG, ZHI LI, JIE LIU, ZHOU, Hong-Hao

“…To determine the frequencies of CYP3A4 alleles (CYP3A4*4,*5 and *6) in Chinese hyperlipidemic patients and to observe the impact of CYP3A4*4 (Ile118Val)…”
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The relative bioavailability and fasting pharmacokinetics of three formulations of olmesartan medoxomil 20-mg capsules and tablets in healthy Chinese male volunteers: An open-label, randomized-sequence, single-dose, three-way crossover study by Li, Kun-Yan, PhD, Liang, Jian-Ping, BS, Hu, Bing-Qiang, PhD, Qiu, Yu, MS, Luo, Chen-Hui, MS, Jiang, Yun, BS, Lin, Xiao-Ping, BS, Yang, Nong, MS

“…Abstract Background: Olmesartan medoxomil is an angiotensin II-receptor antagonist used in the treatment of hypertension. It is a prodrug and is converted to…”
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CYP2C9 allele variants in Chinese hypertension patients and healthy controls by Yu, Bang-ning, Luo, Chen-Hui, Wang, Dan, Wang, An, Li, Zhi, Zhang, Wei, Mo, Wei, Zhou, Hong-Hao

“…Background: Cytochromes P450 (CYP) 2C9 are polymorphic enzymes which catalyze a wide spectrum of drugs. It is also responsible for the metabolism of…”
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Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells by Xia, Li, Liu, Jie-Yang, Yang, Meng-Ying, Zhang, Xue-Hong, Jiang, Yue, Yin, Qian-Qian, Luo, Chen-Hui, Liu, Hong-Chen, Kang, Zhi-Jie, Zhang, Cheng-Tao, Gao, Bei-Bei, Zhou, Ai-Wu, Cai, Hai-Yan, Waller, Edmund K, Yan, Jin-Song, Lu, Ying

“…Osimertinib is a third-generation covalent EGFR inhibitor that is used in treating non-small cell lung cancer. First-generation EGFR inhibitors were found to…”
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Overexpression of TRPM7 is associated with poor prognosis in human ovarian carcinoma by Wang, Jing, Xiao, Ling, Luo, Chen-Hui, Zhou, Hui, Hu, Jun, Tang, Yu-Xi, Fang, Kai-Ning, Zhang, Yi

“…The melastatin-related transient receptor potential 7 channel (TRPM7) is a nonselective cation channel that has been shown to promote tumor metastasis and…”
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Effect of the CYP2C93 allele on lornoxicam metabolism by Liu, Ya-Li, Zhang, Wei, Tan, Zhi-Rong, Ouyang, Dong-Sheng, Luo, Chen-hui, Liu, Zhao-Qian, Qiu, Yu, Chen, Yao, He, Yi-Jing, Zhou, Gan, Zhou, Hong-Hao

“…We investigated whether the CYP2C9 genotypes would affect lornoxicam metabolism in healthy volunteers. Twelve healthy volunteers who had been genotyped for…”
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HE4 and eIF3a Expression Correlates with Surgical Outcome and Overall Survival in Ovarian Cancer Patients with Secondary Cytoreduction by Luo, Chen-Hui, Zhao, Min, Chen, Xiao-Yan, Shahabi, Shohreh, Qiang, Wenan, Zeng, Liang, Wang, Jing, Zhou, Hong-Hao

“…For recurrent ovarian cancer (ROC), secondary cytoreductive surgery (SCS) is recommended as one optional treatment. However, little is known about the…”
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Increased HE4 mRNA Expression Correlates with High Level Of eIF3a mRNA And Better Survival in Women with Epithelial Ovarian Cancer by Luo, Chen-Hui, Zhao, Min, Tang, Yu-Xi, Shahabi, Shohreh, Fang, Kai-Ning, Chen, Yan, Tang, Yan, Chen, Xiao-Yan, Wang, Jing, Zhou, Hong-Hao

“…Human epididymis protein 4 (HE4) is one of the most promising biomarkers for epithelial ovarian cancer (EOC). The majority of previous studies utilized the…”
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Gender specific association of CYP2C93 with hyperlipidaemia in Chinese by Luo, Chen‐Hui, Wang, An, Zhu, Rong‐Hua, Zhang, Wei‐Xia, Mo, Wei, Yu, Bang‐Ning, Chen, Guo‐Lin, Ou‐Yang, Dong‐Sheng, Duan, Xiao‐Hong, El‐Aty, A. M. Abd, Zhou, Hong‐Hao

“…Aims To investigate the association of CYP2C9*3 and *6 with hyperlipidaemia in Chinese. Methods Four hundred and seventy‐six Chinese participated in the study,…”
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CD44v6 promotes β-catenin and TGF-β expression, inducing aggression in ovarian cancer cells by WANG, JING, XIAO, LING, LUO, CHEN-HUI, ZHOU, HUI, ZENG, LIANG, ZHONG, JINGMIN, TANG, YAN, ZHAO, XUE-HENG, ZHAO, MIN, ZHANG, YI

“…A high expression of CD44v6 has been reported in numerous malignant cancers, including stomach, prostate, lung and colon. However, the pathological role and…”
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