Search Results - "Luo, Guanzheng"
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RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
Published in Nature communications (06-05-2019)“…N6-Methyladenosine (m6A) modification has been implicated in the progression of several cancers. We reveal that during epithelial-mesenchymal transition (EMT),…”
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2
Keth-seq for transcriptome-wide RNA structure mapping
Published in Nature chemical biology (01-05-2020)“…RNA secondary structure is critical to RNA regulation and function. We report a new N 3 -kethoxal reagent that allows fast and reversible labeling of…”
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3
Adar Regulates Drosophila melanogaster Spermatogenesis via Modulation of BMP Signaling
Published in International journal of molecular sciences (22-05-2024)“…The dynamic process of spermatogenesis involves asymmetric division, mitosis, and meiosis, which ultimately results in the production of mature spermatozoa…”
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4
Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing
Published in Genome research (01-07-2018)“…N6-Methyladenine (m dA) has been discovered as a novel form of DNA methylation prevalent in eukaryotes; however, methods for high-resolution mapping of m dA…”
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5
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs
Published in Nucleic acids research (18-03-2019)Get full text
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Retraction Note: RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
Published in Nature communications (16-11-2023)Get full text
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7
Dynamics of brassinosteroid response modulated by negative regulator LIC in rice
Published in PLoS genetics (01-04-2012)“…Brassinosteroids (BRs) regulate rice plant architecture, including leaf bending, which affects grain yield. Although BR signaling has been investigated in…”
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8
EpiScan: accurate high-throughput mapping of antibody-specific epitopes using sequence information
Published in NPJ systems biology and applications (09-09-2024)“…The identification of antibody-specific epitopes on virus proteins is crucial for vaccine development and drug design. Nonetheless, traditional wet-lab…”
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9
N6-methyladenosine RNA modification regulates photosynthesis during photodamage in plants
Published in Nature communications (02-12-2022)“…N 6 -methyladenosine (m 6 A) modification of mRNAs affects many biological processes. However, the function of m 6 A in plant photosynthesis remains unknown…”
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10
The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis
Published in Metabolites (06-05-2021)“…The host microbiome plays an important role in regulating physiology through microbiota-derived metabolites during host-microbiome interactions. However,…”
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Investigating and Resolving Cardiotoxicity Induced by COVID‐19 Treatments using Human Pluripotent Stem Cell‐Derived Cardiomyocytes and Engineered Heart Tissues
Published in Advanced science (01-10-2022)“…Coronavirus disease 2019 continues to spread worldwide. Given the urgent need for effective treatments, many clinical trials are ongoing through repurposing…”
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BC10, a DUF266-containing and Golgi-located type II membrane protein, is required for cell-wall biosynthesis in rice (Oryza sativa L.)
Published in The Plant journal : for cell and molecular biology (01-02-2009)“…Glycosyltransferases (GTs) are one of the largest enzyme groups required for the synthesis of complex wall polysaccharides and glycoproteins in plants…”
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13
Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA
Published in Molecular cell (20-06-2019)“…N7-methylguanosine (m7G) is a positively charged, essential modification at the 5′ cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing…”
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14
RETRACTED ARTICLE: RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
Published in Nature communications (06-05-2019)“…N6 -Methyladenosine (m 6 A) modification has been implicated in the progression of several cancers. We reveal that during epithelial-mesenchymal transition…”
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15
Ythdc2 is an N^6-methyladenosine binding protein that regulates mammalian spermatogenesis
Published in Cell research (01-09-2017)“…N^6-methyladenosine (m^6A) is the most common internal modification in eukaryotic mRNA. It is dynamically in- stalled and removed, and acts as a new layer of…”
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16
Bioinformatic analysis of microRNA biogenesis and function related proteins in eleven animal genomes
Published in Journal of genetics and genomics (01-10-2009)“…MicroRNAs are -22 nt long small non-coding RNAs that play important regulatory roles in eukaryotes. The biogenesis and functional processes of microRNAs…”
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17
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs
Published in Nucleic acids research (18-03-2019)“…Abstract Transfer RNA is heavily modified and plays a central role in protein synthesis and cellular functions. Here we demonstrate that ALKBH3 is a…”
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18
Transcriptome-wide Mapping of Internal N 7 -Methylguanosine Methylome in Mammalian mRNA
Published in Molecular cell (20-06-2019)“…N -methylguanosine (m G) is a positively charged, essential modification at the 5' cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m…”
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19
Acute Deletion of METTL14 in β-Cells of Adult Mice Results in Glucose Intolerance
Published in Endocrinology (Philadelphia) (01-10-2019)“…Abstract N6-Methyladenosine (m6A) is the most common and abundant mRNA modification that involves regulating the RNA metabolism. However, the role of m6A in…”
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20
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis
Published in Cell research (01-09-2017)“…N 6 -methyladenosine (m 6 A) is the most common internal modification in eukaryotic mRNA. It is dynamically installed and removed, and acts as a new layer of…”
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