Search Results - "Lunin, Vladimir"

On the suitability of using the diagonal Gaussian approximation in the calculation of the magnitude‐based likelihood function by Lunin, Vladimir Y.

“…Statistical likelihood maximization is currently one of the main tools in computational procedures in biological crystallography. In these procedures, the…”
Get full text

Tuning Spin-Polarized Lifetime in Two-Dimensional Metal–Halide Perovskite through Exciton Binding Energy by Chen, Xihan, Lu, Haipeng, Wang, Kang, Zhai, Yaxin, Lunin, Vladimir, Sercel, Peter C, Beard, Matthew C

“…Metal–halide perovskite semiconductors have attracted attention for opto-spintronic applications where the manipulation of charge and spin degrees of freedom…”
Get full text

Structural biology of human H3K9 methyltransferases by Wu, Hong, Min, Jinrong, Lunin, Vladimir V, Antoshenko, Tatiana, Dombrovski, Ludmila, Zeng, Hong, Allali-Hassani, Abdellah, Campagna-Slater, Valérie, Vedadi, Masoud, Arrowsmith, Cheryl H, Plotnikov, Alexander N, Schapira, Matthieu

“…SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene…”
Get full text

Toward Real Real-Space Refinement of Atomic Models by Urzhumtsev, Alexandre G, Lunin, Vladimir Y

“…High-quality atomic models providing structural information are the results of their refinement versus diffraction data (reciprocal-space refinement), or…”
Get full text

Direct calculation of cryo‐EM and crystallographic model maps for real‐space refinement by Urzhumtsev, Alexandre G., Urzhumtseva, Ludmila M., Lunin, Vladimir Y.

“…This work addresses the problem of the calculation of limited‐resolution maps from an atomic model in cryo‐electron microscopy and in X‐ray and neutron…”
Get full text

Analytic modeling of inhomogeneous-resolution maps in cryo-electron microscopy and crystallography by Urzhumtsev, Alexandre, Lunin, Vladimir Y

“…Refinement of macromolecular atomic models versus experimental maps in crystallography and cryo-electron microscopy is a critical step in structure solution…”
Get full text

Engineering enhanced cellobiohydrolase activity by Taylor, Larry E., Knott, Brandon C., Baker, John O., Alahuhta, P. Markus, Hobdey, Sarah E., Linger, Jeffrey G., Lunin, Vladimir V., Amore, Antonella, Subramanian, Venkataramanan, Podkaminer, Kara, Xu, Qi, VanderWall, Todd A., Schuster, Logan A., Chaudhari, Yogesh B., Adney, William S., Crowley, Michael F., Himmel, Michael E., Decker, Stephen R., Beckham, Gregg T.

“…Glycoside Hydrolase Family 7 cellobiohydrolases (GH7 CBHs) catalyze cellulose depolymerization in cellulolytic eukaryotes, making them key discovery and…”
Get full text

Revealing Nature's Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA by Brunecky, Roman, Alahuhta, Markus, Xu, Qi, Donohoe, Bryon S., Crowley, Michael F., Kataeva, Irina A., Yang, Sung-Jae, Resch, Michael G., Adams, Michael W. W., Lunin, Vladimir V., Himmel, Michael E., Bomble, Yannick J.

“…Most fungi and bacteria degrade plant cell walls by secreting free, complementary enzymes that hydrolyze cellulose; however, some bacteria use large enzymatic…”
Get full text

Structural, mutagenic and in silico studies of xyloglucan fucosylation in Arabidopsis thaliana suggest a water‐mediated mechanism by Urbanowicz, Breeanna R., Bharadwaj, Vivek S., Alahuhta, Markus, Peña, Maria J., Lunin, Vladimir V., Bomble, Yannick J., Wang, Shuo, Yang, Jeong‐Yeh, Tuomivaara, Sami T., Himmel, Michael E., Moremen, Kelley W., York, William S., Crowley, Michael F.

“…Summary The mechanistic underpinnings of the complex process of plant polysaccharide biosynthesis are poorly understood, largely because of the resistance of…”
Get full text

Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis Xylan O-acetyltransferase XOAT1 by Lunin, Vladimir V., Wang, Hsin-Tzu, Bharadwaj, Vivek S., Alahuhta, Markus, Peña, Maria J., Yang, Jeong-Yeh, Archer-Hartmann, Stephanie A., Azadi, Parastoo, Himmel, Michael E., Moremen, Kelley W., York, William S., Bomble, Yannick J., Urbanowicz, Breeanna R.

“…Structural and biochemical analysis of xylan O-acetyltransferase 1 (XOAT1) show that XOAT1 catalyzes xylan acetylation through formation of an acyl-enzyme…”
Get full text

Streamlining heterologous expression of top carbonic anhydrases in Escherichia coli: bioinformatic and experimental approaches by Wei, Hui, Lunin, Vladimir V, Alahuhta, Markus, Himmel, Michael E, Huang, Shu, Bomble, Yannick J, Zhang, Min

“…Carbonic anhydrase (CA) enzymes facilitate the reversible hydration of CO to bicarbonate ions and protons. Identifying efficient and robust CAs and expressing…”
Get full text

Signaling ammonium across membranes through an ammonium sensor histidine kinase by Pflüger, Tobias, Hernández, Camila F., Lewe, Philipp, Frank, Fabian, Mertens, Haydyn, Svergun, Dmitri, Baumstark, Manfred W., Lunin, Vladimir Y., Jetten, Mike S. M., Andrade, Susana L. A.

“…Sensing and uptake of external ammonium is essential for anaerobic ammonium-oxidizing (anammox) bacteria, and is typically the domain of the ubiquitous Amt/Rh…”
Get full text

Resistance to peptidoglycan-degrading enzymes by Grishin, Alexander V, Karyagina, Anna S, Vasina, Daria V, Vasina, Irina V, Gushchin, Vladimir A, Lunin, Vladimir G

“…The spread of bacterial strains resistant to commonly used antibiotics urges the development of novel antibacterial compounds. Ideally, these novel…”
Get more information

Mask‐based approach to phasing of single‐particle diffraction data. II. Likelihood‐based selection criteria by Lunin, Vladimir Y., Lunina, Natalia L., Petrova, Tatiana E., Baumstark, Manfred W., Urzhumtsev, Alexandre G.

“…A new type of mask‐selection criterion is suggested for mask‐based phasing. In this phasing approach, a large number of connected molecular masks are randomly…”
Get full text

Characterization of the Biomass Degrading Enzyme GuxA from Acidothermus cellulolyticus by Hengge, Neal N, Mallinson, Sam J B, Pason, Patthra, Lunin, Vladimir V, Alahuhta, Markus, Chung, Daehwan, Himmel, Michael E, Westpheling, Janet, Bomble, Yannick J

“…Microbial conversion of biomass relies on a complex combination of enzyme systems promoting synergy to overcome biomass recalcitrance. Some thermophilic…”
Get full text

The choice of chromatographic resin for the purification of recombinant lysostaphin affects its activity by Shestak, Nikita V., Grishin, Alexander V., Lyashchuk, Alexander M., Lunin, Vladimir G., Karyagina, Anna S.

“…Lysostaphin is a zinc-dependent endopeptidase that is effective against both antibiotic-sensitive and antibiotic-resistant strains of Staphylococcus aureus…”
Get full text

Introduction to crystallographic refinement of macromolecular atomic models by Urzhumtsev, Alexandre G., Lunin, Vladimir Y.

“…Refinement of atomic models is a necessary step in solving the macromolecular structure by X-ray diffraction methods. Nowadays, high automation and…”
Get full text

Crystallography of Metabolic Enzymes by Alahuhta, Markus, Himmel, Michael E, Bomble, Yannick J, Lunin, Vladimir V

“…The metabolic enzymes like any enzymes generally display globular architecture where secondary structure elements and interactions between them preserve the…”
Get more information

Target highlights in CASP14: Analysis of models by structure providers by Alexander, Leila T., Lepore, Rosalba, Kryshtafovych, Andriy, Adamopoulos, Athanassios, Alahuhta, Markus, Arvin, Ann M., Bomble, Yannick J., Böttcher, Bettina, Breyton, Cécile, Chiarini, Valerio, Chinnam, Naga babu, Chiu, Wah, Fidelis, Krzysztof, Grinter, Rhys, Gupta, Gagan D., Hartmann, Marcus D., Hayes, Christopher S., Heidebrecht, Tatjana, Ilari, Andrea, Joachimiak, Andrzej, Kim, Youngchang, Linares, Romain, Lovering, Andrew L., Lunin, Vladimir V., Lupas, Andrei N., Makbul, Cihan, Michalska, Karolina, Moult, John, Mukherjee, Prasun K., Nutt, William (Sam), Oliver, Stefan L., Perrakis, Anastassis, Stols, Lucy, Tainer, John A., Topf, Maya, Tsutakawa, Susan E., Valdivia‐Delgado, Mauricio, Schwede, Torsten

“…The biological and functional significance of selected Critical Assessment of Techniques for Protein Structure Prediction 14 (CASP14) targets are described by…”
Get full text

Engineering of glycoside hydrolase family 7 cellobiohydrolases directed by natural diversity screening by Brunecky, Roman, Knott, Brandon C., Subramanian, Venkataramanan, Linger, Jeffrey G., Beckham, Gregg T., Amore, Antonella, Taylor, Larry E., Vander Wall, Todd A., Lunin, Vladimir V., Zheng, Fei, Garrido, Mercedes, Schuster, Logan, Fulk, Emily M., Farmer, Samuel, Himmel, Michael E., Decker, Stephen R.

“…Protein engineering and screening of processive fungal cellobiohydrolases (CBHs) remain challenging due to limited expression hosts, synergy-dependency, and…”
Get full text