Search Results - "Lundy, FT"

The neutralising and stimulatory effects of antimicrobial peptide LL-37 in human gingival fibroblasts by Lappin, MJ, Dellett, M., Mills, KI, Lundy, FT, Irwin, CR

“…To investigate the effects of LL-37, a broad spectrum antimicrobial peptide expressed in periodontal tissues, on human gingival fibroblast responsiveness to…”
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aMMP-8 POCT vs. Other Potential Biomarkers in Chair-Side Diagnostics and Treatment Monitoring of Severe Periodontitis by Aji, Nur Rahman Ahmad Seno, Räisänen, Ismo T, Rathnayake, Nilminie, Lundy, Fionnuala T, Mc Crudden, Maelíosa T C, Goyal, Lata, Sorsa, Timo, Gupta, Shipra

“…This study aimed to compare several potential mouthrinse biomarkers for periodontitis including active matrix-metalloproteinase-8 (aMMP-8), total MMP-8, and…”
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In Vivo Regulation of Active Matrix Metalloproteinase-8 (aMMP-8) in Periodontitis: From Transcriptomics to Real-Time Online Diagnostics and Treatment Monitoring by Aji, Nur Rahman Ahmad Seno, Yucel-Lindberg, Tülay, Räisänen, Ismo T, Kuula, Heidi, Nieminen, Mikko T, Mc Crudden, Maelíosa T C, Listyarifah, Dyah, Lundmark, Anna, Lundy, Fionnuala T, Gupta, Shipra, Sorsa, Timo

“…This study investigated in vivo regulation and levels of active matrix metalloproteinase-8 (aMMP-8), a major collagenolytic protease, in periodontitis…”
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Phenotypic differences between oral and skin fibroblasts in wound contraction and growth factor expression by Shannon, Diane B., McKeown, Scott T.W., Lundy, Fionnuala T., Irwin, Chris R.

“…ABSTRACT Wounds of the oral mucosa heal in an accelerated fashion with reduced scarring compared with cutaneous wounds. The differences in healing outcome…”
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PAR-2 Regulates Dental Pulp Inflammation Associated with Caries by Lundy, F.T., About, I., Curtis, T.M., McGahon, M.K., Linden, G.J., Irwin, C.R., El Karim, I.A.

“…Protease-activated receptors (PARs) are G-protein-coupled receptors that are activated enzymatically by proteolysis of an N-terminal domain. The cleavage and…”
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Detection of individual human neutrophil α-defensins (human neutrophil peptides 1, 2 and 3) in unfractionated gingival crevicular fluid—A MALDI-MS approach by Lundy, F.T., Orr, D.F., Shaw, C., Lamey, P.-J., Linden, G.J.

“…The role of antimicrobial peptides is particularly important in the oral cavity where there is constant challenge by microorganisms. The α-defensins are a…”
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NEUROPEPTIDES AND NEUROGENIC MECHANISMS IN ORAL AND PERIODONTAL INFLAMMATION by Lundy, F.T., Linden, G.J.

“…It is generally accepted that the nervous system contributes to the pathophysiology of peripheral inflammation, and a neurogenic component has been implicated…”
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Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth by Awawdeh, L., Lundy, F. T., Shaw, C., Lamey, P-J., Linden, G. J., Kennedy, J. G.

“…Aim The purpose of this study was to investigate the levels of substance P (SP), neurokinin A (NKA) and calcitonin gene‐related peptide (CGRP) in painful and…”
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Identification and overexpression of human neutrophil α-defensins (human neutrophil peptides 1, 2 and 3) in squamous cell carcinomas of the human tongue by Lundy, Fionnuala T., Orr, David F., Gallagher, James R., Maxwell, Perry, Shaw, Chris, Napier, Seamus S., Gerald Cowan, C., Lamey, Philip-John, Marley, John J.

“…To date, little attention has been paid to the possible role of α-defensins (human neutrophil peptides 1-3), HNP-1, HNP-2 and HNP-3 in innate host defence…”
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Radioimmunoassay quantification of adrenomedullin in human gingival crevicular fluid by Lundy, Fionnuala T., O’Hare, Mairead M.T., McKibben, Bronac M., Fulton, Catherine R., Briggs, James E., Linden, Gerard James

“…To investigate whether adrenomedullin (ADM), a multifunctional peptide with key roles in host antimicrobial defence and inflammation, was present and…”
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Caries-induced changes in the expression of pulpal neuropeptide Y by El Karim, Ikhlas A., Lamey, Philip-John, Linden, Gerard J., Awawdeh, Lama A., Lundy, Fionnuala T.

“…Recent evidence suggests that the sympathetic nervous system may have a role in modulating neurogenic inflammation and bone remodelling. Neuropeptide Y (NPY)…”
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Quantitative analysis of MRP-8 in gingival crevicular fluid in periodontal health and disease using microbore HPLC by Lundy, F T, Chalk, R, Lamey, P J, Shaw, C, Linden, G J

“…The protein components of GCF can be separated by reverse-phase microbore HPLC on a C18 column with detection on the basis of 214 nm absorbance. A single major…”
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Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in gingival crevicular fluid associated with painful human teeth by Awawdeh, Lama A., Lundy, Fionnuala T., Linden, Gerard J., Shaw, Chris, Kennedy, John G., Lamey, Philip-John

“…The aim of this study was to investigate the presence of substance P (SP), neurokinin A (NKA) and calcitonin gene‐related peptide (CGRP) in the gingival…”
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Changes in vasoactive intestinal peptide in gingival crevicular fluid in response to periodontal treatment by Linden, Gerard J., Mullally, Brian H., Burden, Donald J., Lamey, Philip-John, Shaw, Christopher, Ardill, Joy, Lundy, Fionnuala T.

“…Aims: To evaluate the role of the anti‐inflammatory neuropeptide vasoactive intestinal peptide (VIP) in periodontal health and disease and to determine the…”
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Changes in substance P and neurokinin A in gingival crevicular fluid in response to periodontal treatment by Lundy, Fionnuala T., Mullally, Brian H., Burden, Donald J., Lamey, Philip-John, Shaw, Christopher, Linden, Gerard J.

“…Background: The study of periodontitis provides a unique model for assessing the involvement of neuropeptides in inflammatory disease. Aim: To investigate the…”
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Substance P and neurokinin A in gingival crevicular fluid in periodontal health and disease by Liinden, Gerard J., McKinneil, Judith, Shaw, Christopher, Lundy, Fionnuala T.

“…The aims of the present study were to investigate whether the tachykin‐ins substance P and neurokinin A were present in gingival crevicular fluid in both…”
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Calcitonin gene-related peptide in gingival crevicular fluid in periodontal health and disease by Lundy, Fionnuala T., Shaw, Christopher, McKinnell, Judith, Lamey, Philip-J., Linden, Gerard J.

“… The aims of the present study were to investigate whether calcitonin gene‐related peptide (CGRP) was present in gingival crevicular fluid in both periodontal…”
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Identification of MRP-8 (calgranulin A) as a major responsive protein in chronic periodontitis by Lundy, Fionnuala T., Chalk, Rod, Lamey, Philip-John, Shaw, Chris, Linden, Gerard J.

“…The purpose of the study was to analyse how the protein composition of the inflammatory exudate associated with chronic periodontitis differed from the exudate…”
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Sjögren’s syndrome: a condition with features of chronic graft-versus-host disease: does duct cell adhesion or permeability play a role in pathogenesis? by Lamey, P.-J, Lundy, F.T, Al-Hashimi, I

“…Primary and Secondary Sjögren’s syndrome are disease complexes characterized by periductal inflammatory cell infiltration of the salivary and lacrimal glands…”
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Extraction and radioimmunoassay quantitation of neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP) from human dental pulp tissue by El-Karim, I, Lundy, F.T, Linden, G.J, Lamey, P.-J

“…The measurement of neuropeptides in complex biological tissue samples requires efficient and appropriate extraction methods so that immunoreactivity is…”
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