Search Results - "Lundy, F. T."

A protocol for the Development of Core Outcome Sets for Endodontic Treatment modalities (COSET): an international consensus process by El Karim, I.A, Duncan, H.F, Cushley, S, Nagendrababu, V, Kirkevang, L.L, Kruse, C, Chong, B.S, Shah, P.K, Lappin, M, McLister, C, Lundy, F.T, Clarke, M

“…Abstract Background The outcome of endodontic treatment is generally assessed using a range of patient and clinician-centred, non-standardised clinical and…”
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The neutralising and stimulatory effects of antimicrobial peptide LL-37 in human gingival fibroblasts by Lappin, MJ, Dellett, M., Mills, KI, Lundy, FT, Irwin, CR

“…To investigate the effects of LL-37, a broad spectrum antimicrobial peptide expressed in periodontal tissues, on human gingival fibroblast responsiveness to…”
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PAR-2 Regulates Dental Pulp Inflammation Associated with Caries by Lundy, F.T., About, I., Curtis, T.M., McGahon, M.K., Linden, G.J., Irwin, C.R., El Karim, I.A.

“…Protease-activated receptors (PARs) are G-protein-coupled receptors that are activated enzymatically by proteolysis of an N-terminal domain. The cleavage and…”
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Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth by Awawdeh, L., Lundy, F. T., Shaw, C., Lamey, P-J., Linden, G. J., Kennedy, J. G.

“…Aim The purpose of this study was to investigate the levels of substance P (SP), neurokinin A (NKA) and calcitonin gene‐related peptide (CGRP) in painful and…”
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Matrix Metalloproteinase-3 Differences in Oral and Skin Fibroblasts by McKeown, S.T.W., Barnes, J.J., Hyland, P.L., Lundy, F.T., Fray, M.J., Irwin, C.R.

“…While skin wounds heal by scarring, wounds of oral mucosa show privileged healing with minimal scar formation. Our hypothesis was that phenotypic differences…”
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Odontoblast cell death induces NLRP3 inflammasome‐dependent sterile inflammation and regulates dental pulp cell migration, proliferation and differentiation by Al Natour, B., Lundy, F. T., Moynah, P. N., About, I., Jeanneau, C., Irwin, C.R., Domberoski, Y., El Karim, I. A.

“…Aim To investigate the ability of dead odontoblasts to initiate NLRP3 inflammasome‐dependent sterile inflammation and to explore the effect on dental pulp cell…”
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A connectivity mapping approach predicted acetylsalicylic acid (aspirin) to induce osteo/odontogenic differentiation of dental pulp cells by Rankin, R., Lundy, F. T., Schock, B. C., Zhang, S.‐D., Al‐Natour, B., About, I., Irwin, C., Linden, G. J., El‐Karim, I. A.

“…Aim To use connectivity mapping, a bioinformatics approach, to identify compounds that could induce odontogenic differentiation of dental pulp cells (DPCs) and…”
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Detection of individual human neutrophil α-defensins (human neutrophil peptides 1, 2 and 3) in unfractionated gingival crevicular fluid—A MALDI-MS approach by Lundy, F.T., Orr, D.F., Shaw, C., Lamey, P.-J., Linden, G.J.

“…The role of antimicrobial peptides is particularly important in the oral cavity where there is constant challenge by microorganisms. The α-defensins are a…”
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Matrix metalloproteinase‐8 activity in gingival crevicular fluid: development of a novel assay by Mc Crudden, M. T. C., Irwin, C. R., El karim, I., Linden, G. J., Lundy, F. T.

“…Background and Objective The matrix metalloproteinases (MMPs) play a role in regulating turnover and metabolism of connective tissues in health but they have…”
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A secretory leukocyte protease inhibitor variant with improved activity against lung infection by Camper, N, Glasgow, A M A, Osbourn, M, Quinn, D J, Small, D M, McLean, D T, Lundy, F T, Elborn, J S, McNally, P, Ingram, R J, Weldon, S, Taggart, C C

“…Secretory leukocyte protease inhibitor (SLPI) is an important respiratory tract host defense protein, which is proteolytically inactivated by excessive…”
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Putative periodontal pathogens in the subgingival plaque of Sudanese subjects with aggressive periodontitis by Hashim, N.T, Linden, G.J, Winning, L, Ibrahim, M.E, Gismalla, B.G, Lundy, F.T, El Karim, I.A

“…Highlights • The article describe the prevalence of putative periodontal pathogens in high risk population for aggressive periodontitis (AgP) using qPCR • The…”
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Interferon-γ stimulates CD14, TLR2 and TLR4 mRNA expression in gingival fibroblasts increasing responsiveness to bacterial challenge by Lappin, M.J, Brown, V, Zaric, S.S, Lundy, F.T, Coulter, W.A, Irwin, C.R

“…Highlights • IFN-γ induces mRNA expression of CD14, TLR2 and TLR4 in human gingival fibroblasts. • IFN-γ induces expression of membrane-bound CD14 in human…”
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Dental pulp fibroblasts express neuropeptide Y Y1 receptor but not neuropeptide Y by Killough, S. A., Lundy, F. T., Irwin, C. R.

“…Killough SA, Lundy FT, Irwin CR. Dental pulp fibroblasts express neuropeptide Y Y1 receptor but not neuropeptide Y. International Endodontic Journal, 43,…”
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Bcl-2 expression in sequential biopsies of potentially malignant oral mucosal lesions assessed by immunocytochemistry by MCALINDEN, R. L, MAXWELL, P, NAPIER, S, HAMILTON, P, COWAN, C. G, LUNDY, F. T, LAMEY, P-J, MARLEY, J. J

“…To examine, for the first time Bcl-2 expression in sequential (autogenous) oral mucosal biopsies taken from the same sites in a gender, risk-factor matched,…”
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Sjögren’s syndrome: a condition with features of chronic graft-versus-host disease: does duct cell adhesion or permeability play a role in pathogenesis? by Lamey, P.-J, Lundy, F.T, Al-Hashimi, I

“…Primary and Secondary Sjögren’s syndrome are disease complexes characterized by periductal inflammatory cell infiltration of the salivary and lacrimal glands…”
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Extraction and radioimmunoassay quantitation of neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP) from human dental pulp tissue by El-Karim, I, Lundy, F.T, Linden, G.J, Lamey, P.-J

“…The measurement of neuropeptides in complex biological tissue samples requires efficient and appropriate extraction methods so that immunoreactivity is…”
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Neuropeptide Y Y1 receptor in human dental pulp cells of noncarious and carious teeth by El Karim, I. A., Lamey, P.-J., Linden, G. J., Lundy, F. T.

“…Aim  To determine the distribution of the NPY Y1 receptor in carious and noncarious human dental pulp tissue using immunohistochemistry. A subsidiary aim was…”
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A comparison of four extraction methods for substance P, neurokinin A and calcitonin gene-related peptide from human dental pulp tissue by Awawdeh, L., Lundy, F.T., Shaw, C., Lamey, P-J., Linden, G.J., Kennedy, J.G.

“…Measuring neuropeptides in biological tissues by radioimmunoassay requires efficient extraction that maintains their immunoreactivity. Many different methods…”
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Evaluation of major parotid glycoproteins in patients with burning mouth syndrome by Lundy, F.T, Al-Hashimi, I, Rees, T.D, Lamey, P-J

“…Objective. This study was to investigate the potential role of salivary glycoproteins in burning mouth syndrome. Study design. This study compared major…”
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An antibody-lectin sandwich assay for quantifying protein glycoforms by LUNDY, F. T, WISDOM, G. B

“…We describe an antibody-lectin sandwich assay for quantitation of glycoforms of proteins. The assay uses deglycosylated IgG antibody immobilized on a…”
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