Search Results - "Lundin, Knut Erik Aslaksen"

The Oslo definitions for coeliac disease and related terms by Ludvigsson, Jonas F, Leffler, Daniel A, Bai, Julio C, Biagi, Federico, Fasano, Alessio, Green, Peter H R, Hadjivassiliou, Marios, Kaukinen, Katri, Kelly, Ciaran P, Leonard, Jonathan N, Lundin, Knut Erik Aslaksen, Murray, Joseph A, Sanders, David S, Walker, Marjorie M, Zingone, Fabiana, Ciacci, Carolina

“…The literature suggests a lack of consensus on the use of terms related to coeliac disease (CD) and gluten. A multidisciplinary task force of 16 physicians…”
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TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences by Dahal-Koirala, Shiva, Balaban, Gabriel, Neumann, Ralf Stefan, Scheffer, Lonneke, Lundin, Knut Erik Aslaksen, Greiff, Victor, Sollid, Ludvig Magne, Qiao, Shuo-Wang, Sandve, Geir Kjetil

“…Abstract T-cell receptor (TCR) sequencing has enabled the development of innovative diagnostic tests for cancers, autoimmune diseases and other applications…”
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Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge by Beitnes, Ann-Christin Røberg, Ráki, Melinda, Brottveit, Margit, Lundin, Knut Erik Aslaksen, Jahnsen, Frode Lars, Sollid, Ludvig Magne

“…Of antigen-presenting cells (APCs) expressing HLA-DQ molecules in the celiac disease (CD) lesion, CD11c(+) dendritic cells (DCs) co-expressing the monocyte…”
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Determination of lower cut‐off levels of adalimumab associated with biochemical remission in Crohn's disease by Carlsen, Arne, Omdal, Roald, Karlsen, Lars, Kvaløy, Jan Terje, Aabakken, Lars, Steinsbø, Øyvind, Bolstad, Nils, Warren, David, Lundin, Knut Erik Aslaksen, Grimstad, Tore

“…Background and Aim Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize…”
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A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease by Schuppan, Detlef, Mäki, Markku, Lundin, Knut E.A, Isola, Jorma, Friesing-Sosnik, Tina, Taavela, Juha, Popp, Alina, Koskenpato, Jari, Langhorst, Jost, Hovde, Øistein, Lähdeaho, Marja-Leena, Fusco, Stefano, Schumann, Michael, Török, Helga P, Kupcinskas, Juozas, Zopf, Yurdagül, Lohse, Ansgar W, Scheinin, Mika, Kull, Karin, Biedermann, Luc, Byrnes, Valerie, Stallmach, Andreas, Jahnsen, Jørgen, Zeitz, Jonas, Mohrbacher, Ralf, Greinwald, Roland

“…In a phase 2 proof-of-concept trial, patients with celiac disease controlled on a gluten-free diet were assigned to one of three dose levels of ZED1227 (a…”
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Detection of gluten immunogenic peptides and the Celiac Disease Adherence Test to monitor gluten-free diet: a pilot study by Skodje, Gry Irene, van Megen, Frida, Stendahl, Marianne, Henriksen, Christine, Lundin, Knut Erik Aslaksen, Veierød, Marit Bragelien

“…Gluten immunogenic peptides (GIP) in feces and/or urine have recently been proposed as a sensitive and specific marker to detect ongoing gluten intake. Here,…”
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Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions by Christophersen, Asbjørn, Lund, Eivind G., Snir, Omri, Solà, Elsa, Kanduri, Chakravarthi, Dahal-Koirala, Shiva, Zühlke, Stephanie, Molberg, Øyvind, Utz, Paul J., Rohani-Pichavant, Mina, Simard, Julia F., Dekker, Cornelia L., Lundin, Knut E. A., Sollid, Ludvig M., Davis, Mark M.

“…Combining HLA-DQ–gluten tetramers with mass cytometry and RNA sequencing analysis, we find that gluten-specific CD4 + T cells in the blood and intestines of…”
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HLA-DQ–Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption by Sarna, Vikas K., Lundin, Knut E.A., Mørkrid, Lars, Qiao, Shuo-Wang, Sollid, Ludvig M., Christophersen, Asbjørn

“…Celiac disease is characterized by HLA-DQ2/8-restricted responses of CD4+ T cells to cereal gluten proteins. A diagnosis of celiac disease based on serologic…”
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Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease by Risnes, Louise F, Christophersen, Asbjørn, Dahal-Koirala, Shiva, Neumann, Ralf S, Sandve, Geir K, Sarna, Vikas K, Lundin, Knut Ea, Qiao, Shuo-Wang, Sollid, Ludvig M

“…Little is known about the repertoire dynamics and persistence of pathogenic T cells in HLA-associated disorders. In celiac disease, a disorder with a strong…”
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A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease by Ting, Yi Tian, Dahal-Koirala, Shiva, Kim, Shi Keshia, Qiao, Shuo-Wang, Neumann, Ralf S., Lundin, Knut E. A., Petersen, Jan, Reid, Hugh H., Sollid, Ludvig M., Rossjohn, Jamie

“…The highly homologous human leukocyte antigen (HLA)-DQ2 molecules, HLA-DQ2.5 and HLA-DQ2.2, are implicated in the pathogenesis of celiac disease (CeD) by…”
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Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort by Kahrs, Christian R, Chuda, Katerina, Tapia, German, Stene, Lars C, Mårild, Karl, Rasmussen, Trond, Rønningen, Kjersti S, Lundin, Knut E A, Kramna, Lenka, Cinek, Ondrej, Størdal, Ketil

“…To determine whether infection with human enterovirus or adenovirus, both common intestinal viruses, predicts development of coeliac disease. Case-control…”
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Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells by Lindeman, Ida, Zhou, Chunyan, Eggesbø, Linn M, Miao, Zhichao, Polak, Justyna, Lundin, Knut E A, Jahnsen, Jørgen, Qiao, Shuo-Wang, Iversen, Rasmus, Sollid, Ludvig M

“…Disease-specific plasma cells (PCs) reactive with transglutaminase 2 (TG2) or deamidated gluten peptides (DGPs) are abundant in celiac disease (CeD) gut…”
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HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge by Sarna, Vikas K, Skodje, Gry I, Reims, Henrik M, Risnes, Louise F, Dahal-Koirala, Shiva, Sollid, Ludvig M, Lundin, Knut E A

“…Initiation of a gluten-free diet without proper diagnostic work-up of coeliac disease is a frequent and demanding problem. Recent diagnostic guidelines suggest…”
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Efficient T cell–B cell collaboration guides autoantibody epitope bias and onset of celiac disease by Iversen, Rasmus, Roy, Bishnudeo, Stamnaes, Jorunn, Høydahl, Lene S., Hnida, Kathrin, Neumann, Ralf S., Korponay-Szabó, Ilma R., Lundin, Knut E. A., Sollid, Ludvig M.

“…B cells play important roles in autoimmune diseases through autoantibody production, cytokine secretion, or antigen presentation to T cells. In most cases, the…”
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Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease by Høydahl, Lene Støkken, Richter, Lisa, Frick, Rahel, Snir, Omri, Gunnarsen, Kristin Støen, Landsverk, Ole J.B., Iversen, Rasmus, Jeliazkov, Jeliazko R., Gray, Jeffrey J., Bergseng, Elin, Foss, Stian, Qiao, Shuo-Wang, Lundin, Knut E.A., Jahnsen, Jørgen, Jahnsen, Frode L., Sandlie, Inger, Sollid, Ludvig M., Løset, Geir Åge

“…Development of celiac disease is believed to involve the transglutaminase-dependent response of CD4+ T cells toward deamidated gluten peptides in…”
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Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping by Gidoni, Moriah, Snir, Omri, Peres, Ayelet, Polak, Pazit, Lindeman, Ida, Mikocziova, Ivana, Sarna, Vikas Kumar, Lundin, Knut E. A., Clouser, Christopher, Vigneault, Francois, Collins, Andrew M., Sollid, Ludvig M., Yaari, Gur

“…Analysis of antibody repertoires by high-throughput sequencing is of major importance in understanding adaptive immune responses. Our knowledge of variations…”
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Outcome measures in coeliac disease trials: the Tampere recommendations by Ludvigsson, Jonas F, Ciacci, Carolina, Green, Peter Hr, Kaukinen, Katri, Korponay-Szabo, Ilma R, Kurppa, Kalle, Murray, Joseph A, Lundin, Knut Erik Aslaksen, Maki, Markku J, Popp, Alina, Reilly, Norelle R, Rodriguez-Herrera, Alfonso, Sanders, David S, Schuppan, Detlef, Sleet, Sarah, Taavela, Juha, Voorhees, Kristin, Walker, Marjorie M, Leffler, Daniel A

“…A gluten-free diet is the only treatment option of coeliac disease, but recently an increasing number of trials have begun to explore alternative treatment…”
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Long‐term efficacy and safety of biosimilar infliximab (CT‐P13) after switching from originator infliximab: open‐label extension of the NOR‐SWITCH trial by Goll, G. L., Jørgensen, K. K., Sexton, J., Olsen, I. C., Bolstad, N., Haavardsholm, E. A., Lundin, K. E. A., Tveit, K. S., Lorentzen, M., Berset, I. P., Fevang, B. T. S., Kalstad, S., Ryggen, K., Warren, D. J., Klaasen, R. A., Asak, Ø., Baigh, S., Blomgren, I. M., Brenna, Ø., Bruun, T. J., Dvergsnes, K., Frigstad, S. O., Hansen, I. M., Hatten, I. S. H., Huppertz‐Hauss, G., Henriksen, M., Hoie, S. S., Krogh, J., Midtgard, I. P., Mielnik, P., Moum, B., Noraberg, G., Poyan, A., Prestegård, U., Rashid, H. U., Strand, E. K., Skjetne, K., Seeberg, K. A., Torp, R., Ystrøm, C. M., Vold, C., Zettel, C. C., Waksvik, K., Gulbrandsen, B., Hagfors, J., Mørk, C., Jahnsen, J., Kvien, T. K.

“…Background and objectives The 52‐week, randomized, double‐blind, noninferiority, government‐funded NOR‐SWITCH trial demonstrated that switching from infliximab…”
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Discriminative T-cell receptor recognition of highly homologous HLA-DQ2–bound gluten epitopes by Dahal-Koirala, Shiva, Ciacchi, Laura, Petersen, Jan, Risnes, Louise Fremgaard, Neumann, Ralf Stefan, Christophersen, Asbjørn, Lundin, Knut E.A., Reid, Hugh H., Qiao, Shuo-Wang, Rossjohn, Jamie, Sollid, Ludvig M.

“…Celiac disease (CeD) provides an opportunity to study the specificity underlying human T-cell responses to an array of similar epitopes presented by the same…”
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Machine Learning Analysis of Naïve B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls by Shemesh, Or, Polak, Pazit, Lundin, Knut E A, Sollid, Ludvig M, Yaari, Gur

“…Celiac disease (CeD) is a common autoimmune disorder caused by an abnormal immune response to dietary gluten proteins. The disease has high heritability. HLA…”
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