Search Results - "Lundin, K. E."
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Celiac disease and risk of fracture in adults—a review
Published in Osteoporosis international (01-06-2014)“…Patients with celiac disease (CD) have low bone mineral density. Evidence of increased fracture risk in these patients is conflicting, and the indication for…”
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Fast and efficient synthesis of Zorro-LNA type 3'-5'-5'-3' oligonucleotide conjugates via parallel in situ stepwise conjugation
Published in Organic & biomolecular chemistry (01-01-2016)“…Zorro-LNA is a new class of therapeutic anti-gene oligonucleotides (ONs) capable of invading supercoiled DNA. The synthesis of single stranded Zorro-LNA is…”
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Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses
Published in Human vaccines & immunotherapeutics (02-12-2017)“…Background: Genetic immunization is expected to induce the expression of antigens in a native form. The encoded peptide epitopes are presented on endogenous…”
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Measuring Understanding of Nanoscience and Nanotechnology: Development and Validation of the Nano-Knowledge Instrument (NanoKI)
Published in Chemistry education research and practice (01-01-2015)“…As the application of nanotechnology in everyday life impacts society, it becomes critical for citizens to have a scientific basis upon which to judge their…”
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Fatty acid–spermine conjugates as DNA carriers for nonviral in vivo gene delivery
Published in Gene therapy (01-12-2009)“…The lack of efficient in vivo gene delivery is a well-known shortcoming of nonviral delivery vectors, in particular of chemical vectors. We developed a series…”
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Cytokine profiles of cultured microvascular endothelial cells from the human intestine
Published in Gut (01-05-1998)“…Background and aims—Cytokine production by endothelial cells has, for practical reasons, been chiefly studied in human umbilical vein endothelial cells (HUVEC)…”
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Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Published in Mucosal immunology (01-11-2016)“…Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency characterized by low immunoglobulin (Ig)G and IgA, and/or IgM…”
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HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
Published in Mucosal immunology (01-11-2010)“…We have analyzed the production of the effector cytokines interleukin (IL)-17, IL-21, and IL-22 in gluten-reactive CD4 + T cells of celiac disease patients,…”
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Diet adherence and gluten exposure in coeliac disease and self-reported non-coeliac gluten sensitivity
Published in Clinical nutrition (Edinburgh, Scotland) (01-02-2017)“…Summary Background/objectives Adherence to gluten-free diet in self reported non-coeliac gluten sensitive subjects is scarcely researched. Objectives of the…”
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TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage
Published in Mucosal immunology (01-05-2016)“…CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key…”
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Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine
Published in Mucosal immunology (01-09-2018)“…The tissue dendritic cell (DC) compartment is heterogeneous, and the ontogeny and functional specialization of human tissue conventional DC (cDC) subsets and…”
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Keratinocyte growth factor and coeliac disease
Published in Gut (01-08-2001)“…BACKGROUND Coeliac disease is characterised by increased epithelial renewal associated with a mucosal T cell response to gliadin. Keratinocyte growth factor…”
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Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease
Published in Mucosal immunology (01-01-2016)“…A hallmark of celiac disease is autoantibodies to transglutaminase 2 (TG2). By visualizing TG2-specific antibodies by antigen staining of affected gut tissue,…”
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Diagnosis and treatment of celiac disease
Published in Mucosal immunology (01-01-2009)“…The understanding of the pathogenesis of celiac disease has made huge advances in recent years. The disease is caused by an inappropriate immune response to…”
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The effects of atorvastatin on gluten‐induced intestinal T cell responses in coeliac disease
Published in Clinical and experimental immunology (01-11-2005)“…Summary Various experimental models suggest that the cholesterol‐lowering drugs statins may also modulate immune responses. Cellular level studies on human…”
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Oats induced villous atrophy in coeliac disease
Published in Gut (01-11-2003)“…The current trend is to allow coeliac disease (CD) patients to introduce oats to their gluten free diet. We sought further data from the clinical setting with…”
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Interferon‐γ‐Secreting T Cells Localize to the Epithelium in Coeliac Disease
Published in Scandinavian journal of immunology (01-12-2002)“…Increased levels of interferon‐γ (IFN‐γ) transcripts have previously been found in duodenal biopsy specimens from patients with untreated coeliac disease (CD)…”
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Density of CD163+CD11c+ Dendritic Cells Increases and CD103+ Dendritic Cells Decreases in the Coeliac Lesion
Published in Scandinavian journal of immunology (01-08-2011)“…Coeliac disease is a chronic inflammation of the intestinal mucosa controlled by gluten‐specific T cells restricted by disease‐associated HLA‐DQ molecules. We…”
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Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
Published in Mucosal immunology (01-09-2013)“…Celiac disease (CD) is a chronic small intestinal inflammation precipitated by gluten ingestion. According to case reports, interferon (IFN)-α administration…”
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