Search Results - "Lundgren, Steinar"

Metabolic characterization of triple negative breast cancer by Cao, Maria D, Lamichhane, Santosh, Lundgren, Steinar, Bofin, Anna, Fjøsne, Hans, Giskeødegård, Guro F, Bathen, Tone F

“…The aims of this study were to characterize the metabolite profiles of triple negative breast cancer (TNBC) and to investigate the metabolite profiles…”
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New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer by Vaidya, Jayant S., Bulsara, Max, Baum, Michael, Wenz, Frederik, Massarut, Samuele, Pigorsch, Steffi, Alvarado, Michael, Douek, Michael, Saunders, Christobel, Flyger, Henrik, Eiermann, Wolfgang, Brew-Graves, Chris, Williams, Norman R., Potyka, Ingrid, Roberts, Nicholas, Bernstein, Marcelle, Brown, Douglas, Sperk, Elena, Laws, Siobhan, Sütterlin, Marc, Corica, Tammy, Lundgren, Steinar, Holmes, Dennis, Vinante, Lorenzo, Bozza, Fernando, Pazos, Montserrat, Blanc-Onfroy, Magali Le, Gruber, Günther, Polkowski, Wojciech, Dedes, Konstantin J., Niewald, Marcus, Blohmer, Jens, McReady, David, Hoefer, Richard, Kelemen, Pond, Petralia, Gloria, Falzon, Mary, Joseph, David, Tobias, Jeffrey S.

“…Background The TARGIT-A trial reported risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy for breast cancer to be as effective…”
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Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer by Lesurf, Robert, Aure, Miriam Ragle, Mørk, Hanne Håberg, Vitelli, Valeria, Sauer, Torill, Geisler, Jürgen, Hofvind, Solveig, Borgen, Elin, Børresen-Dale, Anne-Lise, Engebråten, Olav, Fodstad, Øystein, Garred, Øystein, Geitvik, Gry Aarum, Kåresen, Rolf, Naume, Bjørn, Mælandsmo, Gunhild Mari, Russnes, Hege G., Schlichting, Ellen, Sørlie, Therese, Lingjærde, Ole Christian, Kristensen, Vessela, Sahlberg, Kristine Kleivi, Skjerven, Helle Kristine, Fritzman, Britt, Lundgren, Steinar, Børresen-Dale, Anne-Lise, Kristensen, Vessela, Wärnberg, Fredrik, Hallett, Michael, Sørlie, Therese

“…Breast cancer consists of at least five main molecular “intrinsic” subtypes that are reflected in both pre-invasive and invasive disease. Although previous…”
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Prenatal BRCA1 epimutations contribute significantly to triple-negative breast cancer development by Nikolaienko, Oleksii, Eikesdal, Hans P, Ognedal, Elisabet, Gilje, Bjørnar, Lundgren, Steinar, Blix, Egil S, Espelid, Helge, Geisler, Jürgen, Geisler, Stephanie, Janssen, Emiel A M, Yndestad, Synnøve, Minsaas, Laura, Leirvaag, Beryl, Lillestøl, Reidun, Knappskog, Stian, Lønning, Per E

“…Normal cell BRCA1 epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may have…”
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Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs by Steigedal, Tonje S., Toraskar, Jimita, Redvers, Richard P., Valla, Marit, Magnussen, Synnøve N., Bofin, Anna M., Opdahl, Signe, Lundgren, Steinar, Eckhardt, Bedrich L., Lamar, John M., Doherty, Judy, Hynes, Richard O., Anderson, Robin L., Svineng, Gunbjørg

“…Most cancer patients with solid tumors who succumb to their illness die of metastatic disease. While early detection and improved treatment have led to reduced…”
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The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer by Silwal-Pandit, Laxmi, Nord, Silje, von der Lippe Gythfeldt, Hedda, Møller, Elen K, Fleischer, Thomas, Rødland, Einar, Krohn, Marit, Borgen, Elin, Garred, Øystein, Olsen, Tone, Vu, Phuong, Skjerven, Helle, Fangberget, Anne, Holmen, Marit M, Schlitchting, Ellen, Wille, Elisabeth, Nordberg Stokke, Mette, Moen Vollan, Hans Kristian, Kristensen, Vessela, Langerød, Anita, Lundgren, Steinar, Wist, Erik, Naume, Bjørn, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise, Engebraaten, Olav

“…Chemotherapy-induced alterations to gene expression are due to transcriptional reprogramming of tumor cells or subclonal adaptations to treatment. The effect…”
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Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment by Giskeødegård, Guro F, Madssen, Torfinn S, Sangermani, Matteo, Lundgren, Steinar, Wethal, Torgeir, Andreassen, Trygve, Reidunsdatter, Randi J, Bathen, Tone F

“…The multimodal treatment of breast cancer may induce long term effects on the metabolic profile and increase the risk of future cardiovascular disease. In this…”
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Feasibility of MR metabolomics for immediate analysis of resection margins during breast cancer surgery by Bathen, Tone F, Geurts, Brigitte, Sitter, Beathe, Fjøsne, Hans E, Lundgren, Steinar, Buydens, Lutgarde M, Gribbestad, Ingrid S, Postma, Geert, Giskeødegård, Guro F

“…In this study, the feasibility of high resolution magic angle spinning (HR MAS) magnetic resonance spectroscopy (MRS) of small tissue biopsies to distinguish…”
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Merging transcriptomics and metabolomics--advances in breast cancer profiling by Borgan, Eldrid, Sitter, Beathe, Lingjærde, Ole Christian, Johnsen, Hilde, Lundgren, Steinar, Bathen, Tone F, Sørlie, Therese, Børresen-Dale, Anne-Lise, Gribbestad, Ingrid S

“…Combining gene expression microarrays and high resolution magic angle spinning magnetic resonance spectroscopy (HR MAS MRS) of the same tissue samples enables…”
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Psychosocial interventions as part of breast cancer rehabilitation programs? Results from a systematic review by Fors, Egil A., Bertheussen, Gro F., Thune, Inger, Juvet, Lene K., Elvsaas, Ida-Kristin Ø., Oldervoll, Line, Anker, Gun, Falkmer, Ursula, Lundgren, Steinar, Leivseth, Gunnar

“…Objective: This systematic review aimed to determine the effectiveness of psychoeducation, cognitive behavioural therapy (CBT) and social support interventions…”
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Diffusion-weighted and dynamic contrast-enhanced MRI in evaluation of early treatment effects during neoadjuvant chemotherapy in breast cancer patients by Jensen, Line R., Garzon, Benjamin, Heldahl, Mariann G., Bathen, Tone F., Lundgren, Steinar, Gribbestad, Ingrid S.

“…Purpose: To use dynamic contrast‐enhanced (DCE) and diffusion‐weighted (DW) MRI at 3 Tesla (T) for early evaluation of treatment effects in breast cancer…”
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Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival by Mathiesen, Randi R, Borgen, Elin, Renolen, Anne, Løkkevik, Erik, Nesland, Jahn M, Anker, Gun, Ostenstad, Bjørn, Lundgren, Steinar, Risberg, Terje, Mjaaland, Ingvil, Kvalheim, Gunnar, Lønning, Per Eystein, Naume, Bjørn

“…Presence of disseminated tumor cells (DTCs) in bone marrow (BM) and circulating tumor cells (CTC) in peripheral blood (PB) predicts reduced survival in early…”
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Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer by Knappskog, Stian, Chrisanthar, Ranjan, Løkkevik, Erik, Anker, Gun, Østenstad, Bjørn, Lundgren, Steinar, Risberg, Terje, Mjaaland, Ingvil, Leirvaag, Beryl, Miletic, Hrvoje, Lønning, Per E

“…Mutations affecting p53 or its upstream activator Chk2 are associated with resistance to DNA-damaging chemotherapy in breast cancer. ATM (Ataxia Telangiectasia…”
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Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy by Cao, Maria D, Giskeødegård, Guro F, Bathen, Tone F, Sitter, Beathe, Bofin, Anna, Lønning, Per E, Lundgren, Steinar, Gribbestad, Ingrid S

“…Today's clinical diagnostic tools are insufficient for giving accurate prognosis to breast cancer patients. The aim of our study was to examine the tumor…”
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MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status by BATHEN, Tone F, JENSEN, Line R, SITTER, Beathe, FJÖSNE, Hans E, HALGUNSET, Jostein, AXELSON, David E, GRIBBESTAD, Ingrid S, LUNDGREN, Steinar

“…The purpose of the study was to evaluate the use of metabolic phenotype, described by high-resolution magic angle spinning magnetic resonance spectroscopy (HR…”
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Neural signaling modulates metabolism of gastric cancer by Rabben, Hanne-Line, Andersen, Gøran Troseth, Olsen, Magnus Kringstad, Øverby, Anders, Ianevski, Aleksandr, Kainov, Denis, Wang, Timothy Cragin, Lundgren, Steinar, Grønbech, Jon Erik, Chen, Duan, Zhao, Chun-Mei

“…Tumors comprise cancer cells and the associated stromal and immune/inflammatory cells, i.e., tumor microenvironment (TME). Here, we identify a metabolic…”
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Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer by Vaysse, Charlotte, Lømo, Jon, Garred, Øystein, Fjeldheim, Frøydis, Lofteroed, Trygve, Schlichting, Ellen, McTiernan, Anne, Frydenberg, Hanne, Husøy, Anders, Lundgren, Steinar, Fagerland, Morten W., Richardsen, Elin, Wist, Erik A., Muller, Catherine, Thune, Inger

“…Growing evidence indicates that adiposity is associated with breast cancer risk and negatively affects breast cancer recurrence and survival, a paracrine role…”
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Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel by Chrisanthar, Ranjan, Knappskog, Stian, Løkkevik, Erik, Anker, Gun, Ostenstad, Bjørn, Lundgren, Steinar, Risberg, Terje, Mjaaland, Ingvil, Skjønsberg, Gudbrand, Aas, Turid, Schlichting, Ellen, Fjösne, Hans E, Nysted, Arne, Lillehaug, Johan Richard, Lønning, Per Eystein

“…TP53 mutations have been associated with resistance to anthracyclines but not to taxanes in breast cancer patients. The MDM2 promoter single nucleotide…”
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Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype by Røe, Oluf Dimitri, Anderssen, Endre, Helge, Eli, Pettersen, Caroline Hild, Olsen, Karina Standahl, Sandeck, Helmut, Haaverstad, Rune, Lundgren, Steinar, Larsson, Erik

“…Malignant pleural mesothelioma is considered an almost incurable tumour with increasing incidence worldwide. It usually develops in the parietal pleura, from…”
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CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer by Chrisanthar, Ranjan, Knappskog, Stian, Løkkevik, Erik, Anker, Gun, Østenstad, Bjørn, Lundgren, Steinar, Berge, Elisabet O, Risberg, Terje, Mjaaland, Ingvil, Maehle, Lovise, Engebretsen, Lars Fredrik, Lillehaug, Johan Richard, Lønning, Per Eystein

“…Chemoresistance is the main obstacle to cure in most malignant diseases. Anthracyclines are among the main drugs used for breast cancer therapy and in many…”
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