Search Results - "Lundblad, Mia"

A novel quinoline with airway relaxant effects and anti-inflammatory properties by Bergwik, Jesper, Liu, Jielu, Padra, Médea, Bhongir, Ravi K V, Tanner, Lloyd, Xiang, Yujiao, Lundblad, Mia, Egesten, Arne, Adner, Mikael

“…In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment…”
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First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis by Gottlieb, Alice B, Krueger, James G, Sandberg Lundblad, Mia, Göthberg, Marie, Skolnick, Brett E

“…The current trial was a first-in-human clinical trial evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of the…”
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Biosynthesis of epoxyeicosatrienoic acids varies between polymorphic CYP2C enzymes by Lundblad, Mia Sandberg, Stark, Katarina, Eliasson, Erik, Oliw, Ernst, Rane, Anders

“…Arachidonic acid is oxidized by cytochromes P450 2C (CYP2C) to epoxyeicosatrienoic acids (EETs), possessing vasoactive properties, with 11,12-EET as the…”
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Polymorphism of CYP2D6, CYP2C19, CYP2C9 and CYP2C8 in the Faroese population by HALLING, Jonrit, PETERSEN, Maria S, DAMKIER, Per, NIELSEN, Flemming, GRANDJEAN, Philippe, WEIHE, Pal, LUNDGREN, Stefan, LUNDBLAD, Mia Sandberg, BRØSEN, Kim

“…The purpose of the study was to study the distribution of poor and extensive metabolizers of CYP2C19 and CYP2D6 and to genotype for CYP2C8 and CYP2C9 among 312…”
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Clinical Pharmacokinetics of the Anti-Interleukin-20 Monoclonal Antibody NNC0109-0012 in Healthy Volunteers and Patients with Psoriasis or Rheumatoid Arthritis by Lundblad, Mia Sandberg, Overgaard, Rune Viig, Göthberg, Marie, Fjording, Marianne Scheel, Watson, Estelle

“…Introduction NNC0109-0012, a novel human monoclonal antibody that binds to and neutralizes the activity of interleukin–20, was investigated as a potential…”
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Pharmacokinetic Characterisation Of Recombinant FXIII Across Age Groups In Patients With FXIII Subunit A Congenital Deficiency by Brand-Staufer, Brigitte, Carção, Manuel, Kerlin, Bryce A., Nugent, Diane, Will, Andrew, Williams, Michael, Rosholm, Anders, Lundblad, Mia Sandberg

“…Three trials, F13CD-1725, F13CD-3760 and F13CD-3720 have investigated the pharmacokinetics (PK) of recombinant FXIII (rFXIII), given at a dose of 35 IU/kg once…”
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Reply by Eliasson, Erik, Lundblad, Mia Sandberg

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Differences in CYP2C9 Genotype and Enzyme Activity Between Swedes and Koreans of Relevance for Personalized Medicine: Role of Ethnicity, Genotype, Smoking, Age, and Sex by Hatta, Fazleen H M, Lundblad, Mia, Ramsjo, Margareta, Kang, Ju-Hee, Roh, Hyung-Keun, Bertilsson, Leif, Eliasson, Erik, Aklillu, Eleni

“…Global personalized medicine demands the characterization of person-to-person and between-population differences in drug pharmacokinetics and pharmacodynamics…”
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First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis: e0134703 by Gottlieb, Alice B, Krueger, James G, Lundblad, Mia Sandberg, Gothberg, Marie, Skolnick, Brett E

“…Background The current trial was a first-in-human clinical trial evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary…”
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Accumulation of celecoxib with a 7‐fold higher drug exposure in individuals homozygous for CYP2C93 by Lundblad, Mia Sandberg, Ohlsson, Staffan, Johansson, Peter, Lafolie, Pierre, Eliasson, Erik

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Is celecoxib an inducer of cytochrome P450 3A4 in subjects carrying the CYP2C93 allele? Reply by Eliasson, E, Lundblad, MS

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Interindividual Variation in Drug Metabolism with Focus on Polymorphic Cytochrome P450 2C9 by Lundblad, Mia Sandberg

“…Cytochromes P450 (CYP) are enzymes, mainly catalysing the oxidation of xenobiotics, in order to facilitate their excretion from the body. CYP2C9 is a…”
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