Search Results - "Lund, Jenny"

Skeletal muscle energy metabolism in obesity by Mengeste, Abel M., Rustan, Arild C., Lund, Jenny

“…Comparing energy metabolism in human skeletal muscle and primary skeletal muscle cells in obesity, while focusing on glucose and fatty acid metabolism, shows…”
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A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH by Fraser, David A., Wang, Xiaoyu, Lund, Jenny, Nikolić, Nataša, Iruarrizaga-Lejarreta, Marta, Skjaeret, Tore, Alonso, Cristina, Kastelein, John J.P., Rustan, Arild C., Kim, Yong Ook, Schuppan, Detlef

“…Although long-chain omega-3 fatty acids (LCn-3FAs) regulate inflammatory pathways of relevance to non-alcoholic steatohepatitis (NASH), their susceptibility to…”
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Human HDL subclasses modulate energy metabolism in skeletal muscle cells by Lund, Jenny, Lähteenmäki, Emilia, Eklund, Tiia, Bakke, Hege G, Thoresen, G Hege, Pirinen, Eija, Jauhiainen, Matti, Rustan, Arild C, Lehti, Maarit

“…In addition to its antiatherogenic role, HDL reportedly modulates energy metabolism at the whole-body level. HDL functionality is associated with its structure…”
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Anticoagulation trends in adults aged 65 years and over with atrial fibrillation: a cohort study by Lund, Jenny, Saunders, Catherine L, Edwards, Duncan, Mant, Jonathan

“…ObjectiveTo describe patterns of anticoagulation prescription and persistence for those aged ≥65 years with atrial fibrillation (AF).MethodsDescriptive cohort…”
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Demographic characteristics, long-term health conditions and healthcare experiences of 6333 trans and non-binary adults in England: nationally representative evidence from the 2021 GP Patient Survey by Saunders, Catherine L, Berner, Alison, Lund, Jenny, Mason, Amy M, Oakes-Monger, Tash, Roberts, Meg, Smith, Jack, Duschinsky, Robbie

“…ObjectiveIn order to address the lack of data on the health and healthcare needs of trans and non-binary adults, NHS England includes questions asking about…”
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A medium-chain fatty acid analogue prevents hepatosteatosis and decreases inflammatory lipid metabolites in a murine model of parenteral nutrition-induced hepatosteatosis by Cho, Bennet S, Fligor, Scott C, Fell, Gillian L, Secor, Jordan D, Tsikis, Savas T, Pan, Amy, Yu, Lumeng J, Ko, Victoria H, Dao, Duy T, Anez-Bustillos, Lorenzo, Hirsch, Thomas I, Lund, Jenny, Rustan, Arild C, Fraser, David A, Gura, Kathleen M, Puder, Mark

“…Parenteral (intravenous) nutrition is lifesaving for patients with intestinal failure, but long-term use of parenteral nutrition often leads to liver disease…”
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Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation by Feng, Yuan Z., Lund, Jenny, Li, Yuchuan, Knabenes, Irlin K., Bakke, Siril S., Kase, Eili T., Lee, Yun K., Kimmel, Alan R., Thoresen, G. Hege, Rustan, Arild Christian, Dalen, Knut Tomas

“…Lipid droplet (LD) coating proteins are essential for the formation and stability of intracellular LDs. Plin2 is an abundant LD coating protein in skeletal…”
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Temporal trends in incidence of atrial fibrillation in primary care records: a population-based cohort study by Mendonça, Sílvia C, Saunders, Catherine L, Lund, Jenny, Mant, Jonathan, Edwards, Duncan

“…ObjectivesAtrial fibrillation (AF) is a heart condition associated with a fivefold increased risk of stroke. The condition can be detected in primary care and…”
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Cluster randomised controlled trial of screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the pilot study for the SAFER trial by Williams, Kate, Modi, Rakesh Narendra, Dymond, Andrew, Hoare, Sarah, Powell, Alison, Burt, Jenni, Edwards, Duncan, Lund, Jenny, Johnson, Rachel, Lobban, Trudie, Lown, Mark, Sweeting, Michael J, Thom, H, Kaptoge, Stephen, Fusco, Francesco, Morris, Stephen, Lip, Gregory, Armstrong, Natalie, Cowie, Martin R, Fitzmaurice, David A, Freedman, Ben, Griffin, Simon J, Sutton, Stephen, Hobbs, FD Richard, McManus, Richard J, Mant, Jonathan, SAFER Authorship Group, The

“…IntroductionAtrial fibrillation (AF) is a common arrhythmia associated with 30% of strokes, as well as other cardiovascular disease, dementia and death. AF…”
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Randomised controlled trial of population screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the SAFER trial by Mant, Jonathan, Modi, Rakesh N, Dymond, Andrew, Armstrong, Natalie, Burt, Jenni, Calvert, Peter, Cowie, Martin, Ding, Wern Yew, Edwards, Duncan, Freedman, Ben, Griffin, Simon J, Hoare, Sarah, Hobbs, F D Richard, Johnson, Rachel, Kaptoge, Stephen, Lip, Gregory Y H, Lobban, Trudie, Lown, Mark, Lund, Jenny, McManus, Richard J, Mills, Mark T, Morris, Stephen, Powell, Alison, Proietti, Riccardo, Sutton, Stephen, Sweeting, Mike, Thom, Howard, Williams, Kate

“…IntroductionThere is a lack of evidence that the benefits of screening for atrial fibrillation (AF) outweigh the harms. Following the completion of the…”
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Increased Glycolysis and Higher Lactate Production in Hyperglycemic Myotubes by Lund, Jenny, Ouwens, D Margriet, Wettergreen, Marianne, Bakke, Siril S, Thoresen, G Hege, Aas, Vigdis

“…Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the…”
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The Health and Healthcare Outcomes of Trans and/or Non-Binary Adults in England: Protocol for an Analysis of Responses to the 2021 GP Patient Survey by Saunders, Catherine L., Lund, Jenny, Mason, Amy M., Roberts, Meg, Smith, Jack, Duschinsky, Robbie

“…Background: The large-scale quantitative evidence base to understand and improve health and healthcare outcomes for people who are trans and/or non-binary is…”
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Pancreatic Cancer Cell-Conditioned, Human-Derived Primary Myotubes Display Increased Leucine Turnover, Increased Lipid Accumulation, and Reduced Glucose Uptake by Krapf, Solveig A, Lund, Jenny, Saqib, Awais Ur Rehman, Bakke, Hege G, Rustan, Arild C, Thoresen, G. Hege, Kase, Eili T

“…Metabolic alterations occurring in cancer cells have been seen to also occur in other tissues than cancerous tissue. For instance, cachexia, peripheral insulin…”
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The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells by Mengeste, Abel M., Lund, Jenny, Katare, Parmeshwar, Ghobadi, Roya, Bakke, Hege G., Lunde, Per Kristian, Eide, Lars, Mahony, Gavin O’, Göpel, Sven, Peng, Xiao-Rong, Kase, Eili Tranheim, Thoresen, G. Hege, Rustan, Arild C.

“…A number of studies have highlighted muscle-specific mechanisms of thermogenesis involving futile cycling of Ca2+ driven by sarco (endo)plasmic reticulum…”
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Impaired Metabolic Flexibility in the Osteoarthritis Process: A Study on Transmitochondrial Cybrids by Dalmao-Fernández, Andrea, Lund, Jenny, Hermida-Gómez, Tamara, Vazquez-Mosquera, María E, Rego-Pérez, Ignacio, Blanco, Francisco J, Fernández-Moreno, Mercedes

“…Osteoarthritis (OA) is the most frequent joint disease; however, the etiopathogenesis is still unclear. Chondrocytes rely primarily on glycolysis to meet…”
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SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation by Krapf, Solveig A., Lund, Jenny, Bakke, Hege G., Nyman, Tuula A., Bartesaghi, Stefano, Peng, Xiao-Rong, Rustan, Arild C., Thoresen, G. Hege, Kase, Eili T.

“…Adipose tissue is one of the main regulative sites for energy metabolism. Excess lipid storage and expansion of white adipose tissue (WAT) is the primary…”
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General practitioners' perceptions on opportunistic single-time point screening for atrial fibrillation: A European quantitative survey by Vermunicht, Paulien, Grecu, Mihaela, Deharo, Jean-Claude, Buckley, Claire M, Palà, Elena, Mairesse, Georges H, Farkowski, Michal M, Bergonti, Marco, Pürerfellner, Helmut, Hanson, Coral L, Neubeck, Lis, Freedman, Ben, Witt, Henning, Hills, Mellanie T, Lund, Jenny, Giskes, Katrina, Engler, Daniel, Schnabel, Renate B, Heidbuchel, Hein, Desteghe, Lien

“…There is no clear guidance on how to implement opportunistic atrial fibrillation (AF) screening in daily clinical practice. This study evaluated the perception…”
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SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells by Lund, Jenny, Krapf, Solveig A., Sistek, Medina, Bakke, Hege G., Bartesaghi, Stefano, Peng, Xiao-Rong, Rustan, Arild C., Thoresen, G. Hege, Kase, Eili T.

“…Sentrin-specific protease (SENP) 2 has been suggested as a possible novel drug target for the treatment of obesity and type 2 diabetes mellitus after…”
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Stroke and transient ischaemic attack by Lund, Jenny

“…A stroke is defined by the World Health Organization as a clinical syndrome of rapidly progressing symptoms of cerebral dysfunction, caused by cerebral…”
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Tackling the complexity of gender bias in primary care by Berner, Alison May, Lund, Jenny, Saunders, Catherine L

“…Berner et al discuss the complexity of gender bias in primary care. Sex and gender bias in health care is complex, and research into how to reduce it is…”
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