Search Results - "Lund, Frances E."

The establishment of resident memory B cells in the lung requires local antigen encounter by Allie, S. Rameeza, Bradley, John E., Mudunuru, Uma, Schultz, Michael D., Graf, Beth A., Lund, Frances E., Randall, Troy D.

“…Memory B cells are found in lymphoid and non-lymphoid tissues, suggesting that some may be tissue-resident cells. Here we show that pulmonary influenza…”
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Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation by Ballesteros-Tato, André, León, Beatriz, Graf, Beth A., Moquin, Amy, Adams, Pamela Scott, Lund, Frances E., Randall, Troy D.

“…T follicular helper (Tfh) cells promote T cell-dependent humoral immune responses by providing T cell help to B cells and by promoting germinal center (GC)…”
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Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus by Jenks, Scott A., Cashman, Kevin S., Zumaquero, Esther, Marigorta, Urko M., Patel, Aakash V., Wang, Xiaoqian, Tomar, Deepak, Woodruff, Matthew C., Simon, Zoe, Bugrovsky, Regina, Blalock, Emily L., Scharer, Christopher D., Tipton, Christopher M., Wei, Chungwen, Lim, S. Sam, Petri, Michelle, Niewold, Timothy B., Anolik, Jennifer H., Gibson, Greg, Lee, F. Eun-Hyung, Boss, Jeremy M., Lund, Frances E., Sanz, Ignacio

“…Systemic Lupus Erythematosus (SLE) is characterized by B cells lacking IgD and CD27 (double negative; DN). We show that DN cell expansions reflected a subset…”
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Blimp-1-dependent and -independent natural antibody production by B-1 and B-1-derived plasma cells by Savage, Hannah P, Yenson, Vanessa M, Sawhney, Sanjam S, Mousseau, Betty J, Lund, Frances E, Baumgarth, Nicole

“…Natural antibodies contribute to tissue homeostasis and protect against infections. They are secreted constitutively without external antigenic stimulation…”
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Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion by Nguyen, Doan C., Garimalla, Swetha, Xiao, Haopeng, Kyu, Shuya, Albizua, Igor, Galipeau, Jacques, Chiang, Kuang-Yueh, Waller, Edmund K., Wu, Ronghu, Gibson, Greg, Roberson, James, Lund, Frances E., Randall, Troy D., Sanz, Iñaki, Lee, F. Eun-Hyung

“…Human antibody-secreting cells (ASC) in peripheral blood are found after vaccination or infection but rapidly apoptose unless they migrate to the bone marrow…”
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Human Leukocyte Antigen Class I and II Knockout Human Induced Pluripotent Stem Cell-Derived Cells: Universal Donor for Cell Therapy by Mattapally, Saidulu, Pawlik, Kevin M, Fast, Vladimir G, Zumaquero, Esther, Lund, Frances E, Randall, Troy D, Townes, Tim M, Zhang, Jianyi

“…Background We aim to generate a line of "universal donor" human induced pluripotent stem cells (hi PSC s) that are nonimmunogenic and, therefore, can be used…”
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Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model by Blacher, Eran, Dadali, Tulin, Bespalko, Alina, Haupenthal, Viola J., Grimm, Marcus O. W., Hartmann, Tobias, Lund, Frances E., Stein, Reuven, Levy, Ayelet

“…Objective Alzheimer's disease (AD)‐associated dementia is due to tissue damage caused by amyloid β (Aβ) deposition within the brain and by accompanying…”
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Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus by LaMere, Mark W, Lam, Ho-Tak, Moquin, Amy, Haynes, Laura, Lund, Frances E, Randall, Troy D, Kaminski, Denise A

“…Influenza A virus causes recurring seasonal epidemics and occasional influenza pandemics. Because of changes in envelope glycoprotein Ags, neutralizing Abs…”
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Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T Cells by Ballesteros-Tato, André, León, Beatriz, Lee, Byung O., Lund, Frances E., Randall, Troy D.

“…Memory CD8+ T cells are programmed during the primary response for robust secondary responsiveness. Here we show that CD8+ T cells responding to different…”
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Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival by Schultz, Michael D, Dadali, Tulin, Jacques, Sylvain A, Muller-Steffner, Hélène, Foote, Jeremy B, Sorci, Leonardo, Kellenberger, Esther, Botta, Davide, Lund, Frances E

“…NAD, a key co-enzyme required for cell metabolism, is synthesized via two pathways in most organisms. Since schistosomes apparently lack enzymes required for…”
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Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity by Randall, Troy D, Moyron-Quiroz, Juan E, Rangel-Moreno, Javier, Kusser, Kim, Hartson, Louise, Sprague, Frank, Goodrich, Stephen, Woodland, David L, Lund, Frances E

“…Bronchus-associated lymphoid tissue (BALT) is occasionally found in the lungs of mice and humans; however, its role in respiratory immunity is unknown. Here we…”
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Chitinase 3-like-1 protects airway function despite promoting type 2 inflammation during fungal-associated allergic airway inflammation by Mackel, Joseph J, Garth, Jaleesa M, Jones, MaryJane, Ellis, Diandra A, Blackburn, Jonathan P, Yu, Zhihong, Matalon, Sadis, Curtiss, Miranda, Lund, Frances E, Hastie, Annette T, Meyers, Deborah A, Steele, Chad

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Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity by Lund, Frances E

“…The 5th international CD38 meeting, held in Torino, Italy, spanned a range of topics from the role of CD38 as a signaling receptor in lymphocytic tumors to the…”
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Chitinase-3-like 1 regulates TH2 cells, TFH cells and IgE responses to helminth infection by Curtiss, Miranda L., Rosenberg, Alexander F., Scharer, Christopher D., Mousseau, Betty, Benavides, Natalia A. Ballesteros, Bradley, John E., León, Beatriz, Steele, Chad, Randall, Troy D., Lund, Frances E.

“…Introduction Data from patient cohorts and mouse models of atopic dermatitis, food allergy and asthma strongly support a role for chitinase-3-like-1 protein…”
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Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus by Jenks, Scott A., Cashman, Kevin S., Zumaquero, Esther, Marigorta, Urko M., Patel, Aakash V., Wang, Xiaoqian, Tomar, Deepak, Woodruff, Matthew C., Simon, Zoe, Bugrovsky, Regina, Blalock, Emily L., Scharer, Christopher D., Tipton, Christopher M., Wei, Chungwen, Lim, S. Sam, Petri, Michelle, Niewold, Timothy B., Anolik, Jennifer H., Gibson, Greg, Eun-Hyung Lee, F., Boss, Jeremy M., Lund, Frances E., Sanz, Ignacio

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Regulation of Antinucleoprotein IgG by Systemic Vaccination and Its Effect on Influenza Virus Clearance by Lamere, Mark W, Moquin, Amy, Lee, F Eun-Hyung, Misra, Ravi S, Blair, Patrick J, Haynes, Laura, Randall, Troy D, Lund, Frances E, Kaminski, Denise A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Persistence and Responsiveness of Immunologic Memory in the Absence of Secondary Lymphoid Organs by Moyron-Quiroz, Juan E., Rangel-Moreno, Javier, Hartson, Louise, Kusser, Kim, Tighe, Michael P., Klonowski, Kimberly D., Lefrançois, Leo, Cauley, Linda S., Harmsen, Allen G., Lund, Frances E., Randall, Troy D.

“…Secondary lymphoid organs (SLOs) promote primary immune responses by recruiting naive lymphocytes and activated APCs. However, their role in the persistence or…”
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CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism by García-Rodríguez, Sonia, Rosal-Vela, Antonio, Botta, Davide, Cumba Garcia, Luz M., Zumaquero, Esther, Prados-Maniviesa, Verónica, Cerezo-Wallis, Daniela, Lo Buono, Nicola, Robles-Guirado, José-Ángel, Guerrero, Salvador, González-Paredes, Elena, Andrés-León, Eduardo, Corbí, Ángel, Mack, Matthias, Koch-Nolte, Friedrich, Merino, Ramón, Zubiaur, Mercedes, Lund, Frances E., Sancho, Jaime

“…In this study, we investigated the role of CD38 in a pristane-induced murine model of lupus. CD38-deficient ( Cd38 −/− ) but not ART2-deficient ( Art2 −/− )…”
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Dual Role of CD38 in Microglial Activation and Activation-Induced Cell Death by Mayo, Lior, Jacob-Hirsch, Jasmine, Amariglio, Ninette, Rechavi, Gideon, Moutin, Marie-Jo, Lund, Frances E, Stein, Reuven

“…Microglia, the resident immune cells of the CNS, are normally quiescent but become activated after infection or injury. Their properties then change, and they…”
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A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts by Schultz, Michael D., Suschak, John J., Botta, Davide, Silva-Sanchez, Aaron, King, R. Glenn, Detchemendy, Thomas W., Meshram, Chetan D., Foote, Jeremy B., Zhou, Fen, Tipper, Jennifer L., Zhang, Jianfeng, Harrod, Kevin S., Leal, Sixto M., Randall, Troy D., Roberts, M. Scot, Georges, Bertrand, Lund, Frances E.

“…The coronavirus disease 2019 (COVID-19) pandemic has illustrated the critical need for effective prophylactic vaccination to prevent the spread of severe acute…”
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