Performance of quantitative ultrasound in the discrimination of prevalent osteoporotic fractures in a bone metabolic unit

Performance of quantitative ultrasound in the discrimination of prevalent osteoporotic fractures in a bone metabolic unit

There is a growing interest in ultrasound evaluation of bone status as an alternative to the measurement with dual X-ray absorptiometry (DXA), due to its low cost, portability, and nonionizing radiation. The aim of our study was to investigate the relation among DXA, QUS, clinical, anthropometric, a...

Full description

Saved in:
Bibliographic Details
Published in:Bone (New York, N.Y.) Vol. 32; no. 5; pp. 571 - 578
Main Authors: López-Rodríguez, F, Mezquita-Raya, P, Luna, J.de Dios, Escobar-Jiménez, F, Muñoz-Torres, M
Format: Journal Article
Language:English
Published: New York, NY Elsevier Inc 01-05-2003
Elsevier Science
Subjects:
Absorptiometry, Photon
Adult
Aged
Aged, 80 and over
Anthropometry
Biological and medical sciences
Bone Density
Bone mineral density
Female
Femoral Neck Fractures - diagnostic imaging
Femoral Neck Fractures - epidemiology
Femur Neck - diagnostic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Joints
Life Style
Lumbar Vertebrae - diagnostic imaging
Male
Medical sciences
Middle Aged
Osteoporosis
Osteoporosis - diagnostic imaging
Osteoporosis - epidemiology
Osteoporotic fracture
Quantitative ultrasound
QUI T-score
Risk Factors
Sensitivity and Specificity
Ultrasonic investigative techniques
Ultrasonography
Osteoporosis
Bone mineral density
Quantitative ultrasound
Osteoporotic fracture
QUI T-score
Sonography
Human
Methodology
Ultrasound imaging
Diseases of the osteoarticular system
Lower limb
Bone disease
Fracture
Test reliability
Trauma
Hip
Sensitivity
Specificity
Risk factor
Complication
Diagnosis
Bone
Elderly
Quantitative analysis
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There is a growing interest in ultrasound evaluation of bone status as an alternative to the measurement with dual X-ray absorptiometry (DXA), due to its low cost, portability, and nonionizing radiation. The aim of our study was to investigate the relation among DXA, QUS, clinical, anthropometric, and lifestyle factors, and to determine QUS cutoff values in order to discriminate fractures in patients referred to the Bone Metabolic Unit at an Endocrinology Service. We studied 300 patients (281 females and 19 males; age 58 ± 11 years) referred for evaluation of osteoporosis. In all cases we determined basic anthropometric parameters, a clinical history including previous osteoporotic fractures and risk factors for osteoporosis, and QUS parameters in calcaneus (Hologic Sahara), and BMD in lumbar spine (LS) and femoral neck (FN), by DXA (Hologic QDR 1000). Using the WHO densitometric criteria, 37, 46.7, and 16.3% of our population were osteoporotic, osteopenic, and normal, respectively. A QUI T-score ≤−1.5 SD provided a sensitivity of 68.9% and a specificity of 64.7% for osteoporotic fracture discrimination and a sensitivity of 64.9% and a specificity of 74.1% for osteoporosis defined by WHO criteria using DXA. In the logistic regression, the presence of family history of fragility fractures (OR: 3.03; CI 95%: 1.3–7.03), a DXA T-score ≤−2.5 (OR: 3.58; CI 95%: 1.66–7.73), and a QUI T-score ≤−1.5 (OR: 2.56; CI 95%: 1.15–5.69) were independently associated with prevalent osteoporotic fractures. In conclusion, calcaneus ultrasound appears as a useful technique for the routine clinical practice, as its performance is similar to DXA for the discrimination of subjects with osteoporotic fracture.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:8756-3282
1873-2763
DOI:10.1016/S8756-3282(03)00058-9