Search Results - "Lumsden, Ailsa"
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Risk of COVID-19 death in cancer patients: an analysis from Guy’s Cancer Centre and King’s College Hospital in London
Published in British journal of cancer (28-09-2021)“…Background Using an updated dataset with more patients and extended follow-up, we further established cancer patient characteristics associated with COVID-19…”
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COVID-19 Risk Factors for Cancer Patients: A First Report with Comparator Data from COVID-19 Negative Cancer Patients
Published in Cancers (19-05-2021)“…Very few studies investigating COVID-19 in cancer patients have included cancer patients as controls. We aimed to identify factors associated with the risk of…”
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Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer
Published in Human molecular genetics (15-07-2012)“…MicroRNAs (miRs) play an important role in the development of many complex human diseases and may have tumour suppressor or oncogenic (oncomir) properties…”
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COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry
Published in Therapeutic advances in medical oncology (2021)“…Background: Cancer patients are at higher risk of COVID-19 complications and mortality than the rest of the population. Breast cancer patients seem to have…”
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Factors Affecting COVID-19 Outcomes in Cancer Patients: A First Report From Guy's Cancer Center in London
Published in Frontiers in oncology (22-07-2020)“…There is insufficient evidence to support clinical decision-making for cancer patients diagnosed with COVID-19 due to the lack of large studies. We used data…”
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Previous immune checkpoint inhibitor therapy is associated with decreased COVID-19-related hospitalizations and complications in patients with cancer: Results of a propensity-matched analysis of the OnCovid registry
Published in International journal of infectious diseases (01-02-2024)“…To date, studies have not provided definitive answers regarding whether previous immune checkpoint inhibitor (ICI) treatment alters outcomes for cancer…”
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Impact of SARS-CoV-2 vaccines and recent chemotherapy on COVID-19 morbidity and mortality in patients with soft tissue sarcoma: an analysis from the OnCovid registry
Published in Therapeutic advances in medical oncology (2024)“…To date, limited evidence exists on the impact of COVID-19 in patients with soft tissue sarcoma (STS), nor about the impact of SARS-CoV-2 vaccines and recent…”
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Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: a joint analysis of OnCovid and ESMO-CoCARE registries
Published in Journal for immunotherapy of cancer (01-11-2022)“…BackgroundAs management and prevention strategies against COVID-19 evolve, it is still uncertain whether prior exposure to immune checkpoint inhibitors (ICIs)…”
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MiR-27a-3p: An AR-modulatory microRNA with a distinct role in prostate cancer progression and therapy
Published in Journal of clinical oncology (20-02-2020)“…Abstract only 193 Background: Prostate cancer (PCa) is an androgen dependent malignancy. PCa patients initially respond to androgen ablation but eventually the…”
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Amplification-Free Detection of Circulating microRNA Biomarkers from Body Fluids Based on Fluorogenic Oligonucleotide-Templated Reaction between Engineered Peptide Nucleic Acid Probes: Application to Prostate Cancer Diagnosis
Published in Analytical chemistry (Washington) (16-08-2016)“…Highly abundant in cells, microRNAs (or miRs) play a key role as regulators of gene expression. A proportion of them are also detectable in biofluids making…”
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Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer
Published in British journal of cancer (09-11-2022)“…Background Consolidated evidence suggests spontaneous immunity from SARS-CoV-2 is not durable, leading to the risk of reinfection, especially in the context of…”
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Long-term effects of COVID-19 on cancer patients: the experience from Guy's Cancer Centre
Published in Future oncology (London, England) (01-10-2022)“…Few studies have investigated the long-term effects of COVID-19 on cancer patients. The authors conducted a telephone survey on the long-term symptoms of…”
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Pandemic Phase-Adjusted Analysis of COVID-19 Outcomes Reveals Reduced Intrinsic Vulnerability and Substantial Vaccine Protection From Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Breast Cancer
Published in Journal of clinical oncology (20-05-2023)“…Although representing the majority of newly diagnosed cancers, patients with breast cancer appear less vulnerable to COVID-19 mortality compared with other…”
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A signature of miRNAs in the blood to help prognosticate prostate cancer at the time of diagnosis
Published in Journal of clinical oncology (20-05-2017)“…Abstract only e16558 Background: Prostate cancer (PCa) is the most commonly diagnosed cancer in men. Around 80% of PCas are diagnosed as early, localised stage…”
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Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom
Published in Journal of clinical oncology (01-10-2023)“…There is limited evidence regarding the prognostic effects of pathologic lymph node (LN) regression after neoadjuvant chemotherapy for esophageal…”
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Clinical effectiveness of SARS-CoV-2 vaccines and booster doses in patients with cancer: An analysis from the European OnCovid registry
Published in Journal of clinical oncology (01-06-2022)“…e18725 Background: Immunogenicity and safety of SARS-CoV-2 vaccines have been widely investigated in patients (pts) with cancer. However, their effectiveness…”
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A circulating miRNA signature to help prognosticate at prostate cancer diagnosis
Published in Journal of clinical oncology (20-02-2017)“…Abstract only 108 Background: Prostate cancer (PCa) is the most commonly diagnosed cancer in men. Around 80% of PCas are diagnosed as early, localised stage…”
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Time-Dependent COVID-19 Mortality in Patients With Cancer: An Updated Analysis of the OnCovid Registry
Published in JAMA oncology (01-01-2022)“…Whether the severity and mortality of COVID-19 in patients with cancer have improved in terms of disease management and capacity is yet to be defined. To test…”
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Palbociclib and endocrine therapy in heavily pretreated hormone receptor-positive HER2-negative advanced breast cancer: the UK Compassionate Access Programme experience
Published in Breast cancer research and treatment (01-04-2019)“…Purpose Palbociclib is approved in 1st line for hormone receptor (HR)-positive HER2-negative advanced breast cancer (ABC). A Compassionate Access Programme…”
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Determinants of enhanced vulnerability to Covid-19 in U.K. cancer patients: Results from the OnCovid study
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 1574 Background: Despite high contagiousness and rapid spread, SARS-Cov-2 has led to heterogeneous outcomes across affected nations. Within…”
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