Search Results - "Lummus, Zana L"

Pathogenesis and Disease Mechanisms of Occupational Asthma by Lummus, Zana L., PhD, Wisnewski, Adam V., PhD, Bernstein, David I., MD

“…Occupational asthma (OA) is one of the most common forms of work-related lung disease in all industrialized nations. The clinical management of patients with…”
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Next Generation DNA Sequencing of Novel Loci in Workers with Diisocyanate Asthma (DA) by Lummus, Zana L., PhD, Kaufman, Kenneth, PhD, Weirauch, Matthew T., PhD, Cartier, Andre, MD, FAAAAI, Cruz, Maria-Jesús, MD, Kesavalu, Banu, MS, Lemiere, Catherine, MD, Muñoz, Xavier, MD, Perez-Camo, Ignacio, MD, Quirce, Santiago, MD, PhD, Sastre, Joaquin, MD, PhD, FAAAAI, Yucesoy, Berran, PhD, Bernstein, David I., MD, FAAAAI

“…Transcriptomic analysis was carried out for the top 70 DA associated SNPs using available transcription factor (TF) datasets from relevant lung-derived tissues…”
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Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor α by Bernstein, David I., MD, Kissling, Grace E., PhD, Khurana Hershey, Gurjit, MD, PhD, Yucesoy, Berran, PhD, Johnson, Victor J., PhD, Cartier, André, MD, Gautrin, Denyse, PhD, Sastre, Joaquin, MD, Boulet, Louis-Philippe, MD, Malo, Jean-Luc, MD, Quirce, Santiago, MD, Tarlo, Susan M., MBBS, Langmeyer, Stacy, MS, Luster, Michael I., PhD, Lummus, Zana L., PhD

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Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma by Yucesoy, Berran, Kaufman, Kenneth M, Lummus, Zana L, Weirauch, Matthew T, Zhang, Ge, Cartier, André, Boulet, Louis-Philippe, Sastre, Joaquin, Quirce, Santiago, Tarlo, Susan M, Cruz, Maria-Jesus, Munoz, Xavier, Harley, John B, Bernstein, David I

“…Diisocyanates, reactive chemicals used to produce polyurethane products, are the most common causes of occupational asthma. The aim of this study is to…”
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Comparison of biological effects with albumin adducts of 4,4′-methylenediphenyl diisocyanate in workers by Sabbioni, Gabriele, Vanimireddy, Lakshiminiranjan Reddy, Lummus, Zana L., Bernstein, David I.

“…Lung sensitization and asthma are the main health effects of 4,4′-methylenediphenyl diisocyanate (MDI). Albumin adducts (isocyanate-specific adducts) of MDI…”
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Genetic variants with gene regulatory effects are associated with diisocyanate-induced asthma by Bernstein, David I., Lummus, Zana L., Kesavalu, Banu, Yao, Jianbo, Kottyan, Leah, Miller, Daniel, Cartier, André, Cruz, Maria-Jesús, Lemiere, Catherine, Muñoz, Xavier, Quirce, Santiago, Tarlo, Susan, Sastre, Joaquin, Boulet, Louis Philippe, Weirauch, Matthew T., Kaufman, Kenneth

“…Isocyanates are major causes of occupational asthma, but susceptibility and mechanisms of diisocyanate-induced asthma (DA) remain uncertain. The aim of this…”
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Interferon-γ promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma by Ouyang, Bin, Bernstein, David I, Lummus, Zana L, Ying, Jun, Boulet, Louis-Philippe, Cartier, André, Gautrin, Denyse, Ho, Shuk-Mei

“…Risk factors have not been identified that determine susceptibility for development of diisocyanate-induced occupational asthma (DA). We hypothesized that…”
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Regulatory Variants of ATF3, CDH17 and FAM71A are Risk Factors for Diisocyanate Induced Occupational Asthma (DA) by Lummus, Zana L., Kesavalu, Banu, Kaufman, Kenneth, Yao, Jianbo, Weirauch, Matthew T., Kottyan, Leah C., Miller, Daniel, Cartier, André, Cruz, Maria-Jesus, Lemiere, Catherine, Muñoz, Xavier, Quirce, Santiago, Sastre, Joaquin, Tarlo, Susan M., Bernstein, David I.

“…Rationale Using Next Generation Sequencing (NGS) we identified non-coding SNPs associated with confirmed DA that might impact gene expression via transcription…”
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CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population by Bernstein, David I, Kashon, Michael, Lummus, Zana L, Johnson, Victor J, Fluharty, Kara, Gautrin, Denyse, Malo, Jean-Luc, Cartier, André, Boulet, Louis-Philippe, Sastre, Joaquin, Quirce, Santiago, Germolec, Dori, Tarlo, Susan M, Cruz, Maria-Jesus, Munoz, Xavier, Luster, Michael I, Yucesoy, Berran

“…Recently, a genome-wide association study (GWAS) conducted in Korean subjects identified four CTNNA3 (alpha-T catenin) single nucleotide polymorphisms (SNPs)…”
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Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma by Yucesoy, Berran, Johnson, Victor J, Lummus, Zana L, Kissling, Grace E, Fluharty, Kara, Gautrin, Denyse, Malo, Jean-Luc, Cartier, André, Boulet, Louis-Philippe, Sastre, Joaquin, Quirce, Santiago, Germolec, Dori R, Tarlo, Susan M, Cruz, Maria-Jesus, Munoz, Xavier, Luster, Michael I, Bernstein, David I

“…Diisocyanates are a common cause of occupational asthma, but risk factors are not well defined. A case-control study was conducted to investigate whether…”
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A case of progesterone-induced anaphylaxis, cyclic urticaria/angioedema, and autoimmune dermatitis by Bernstein, I Leonard, Bernstein, David I, Lummus, Zana L, Bernstein, Jonathan A

“…Women have exhibited anaphylaxis, urticaria/angioedema, and autoimmune progesterone dermatitis (APD) coinciding with the progesterone premenstrual rise. We…”
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Genetic Variants in the Major Histocompatibility Complex Class I and Class II Genes Are Associated With Diisocyanate-Induced Asthma by Yucesoy, Berran, Johnson, Victor J., Lummus, Zana L., Kashon, Michael L., Rao, Marepalli, Bannerman-Thompson, Hansen, Frye, Bonnie, Wang, Wei, Gautrin, Denyse, Cartier, André, Boulet, Louis-Philippe, Sastre, Joaquin, Quirce, Santiago, Tarlo, Susan M., Germolec, Dori R., Luster, Michael I., Bernstein, David I.

“…OBJECTIVE:To investigate the association between single nucleotide polymorphisms (SNPs) located across the major histocompatibility complex and susceptibility…”
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Influence of dog ownership and high endotoxin on wheezing and atopy during infancy by Campo, Paloma, Kalra, Harpinder K., Levin, Linda, Reponen, Tiina, Olds, Rolanda, Lummus, Zana L., Cho, Seung-Hyun, Khurana Hershey, Gurjit K., Lockey, James, Villareal, Manuel, Stanforth, Sherry, LeMasters, Grace, Bernstein, David I.

“…Increased exposure to microbial products early in life may protect from development of atopic disorders in childhood. Few studies have examined the…”
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N-Acetyltransferase 2 Genotypes Are Associated With Diisocyanate-Induced Asthma by Yucesoy, Berran, Kissling, Grace E., Johnson, Victor J., Lummus, Zana L., Gautrin, Denyse, Cartier, André, Boulet, Louis-Philippe, Sastre, Joaquin, Quirce, Santiago, Tarlo, Susan M., Cruz, Maria-Jesus, Munoz, Xavier, Luster, Michael I., Bernstein, David I.

“…OBJECTIVE:To investigate whether genetic variants of N-acetyltransferase (NAT) genes are associated with diisocyanate asthma (DA). METHODS:The study population…”
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Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthma by Yucesoy, Berran, Kashon, Michael L, Johnson, Victor J, Lummus, Zana L, Fluharty, Kara, Gautrin, Denyse, Cartier, André, Boulet, Louis-Philippe, Sastre, Joaquin, Quirce, Santiago, Tarlo, Susan M, Cruz, Maria-Jesus, Munoz, Xavier, Luster, Michael I, Bernstein, David I

“…Diisocyanates are the most common cause of occupational asthma, but risk factors are not well defined. A case-control study was conducted to investigate…”
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Communities near toluene diisocyanate sources: an investigation of exposure and health by Wilder, Lynn C, Langley, Ricky L, Middleton, Dan C, Ernst, Kathleen, Lummus, Zana L, Streicher, Robert P, Campbell, Douglas S, Wattigney, Wendy A, Bernstein, Jonathan A, Bernstein, David I, Dearwent, Steve M

“…Toluene diisocyanate (TDI) is a well-known cause of occupational asthma, but we know little about the potential for exposure and health effects among residents…”
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Advances in methods used in evaluation of occupational asthma by Campo, Paloma, Lummus, Zana L, Bernstein, David I

“…PURPOSE OF REVIEWDiagnosing occupational asthma (OA) is a complex undertaking, the primary goal of which is to demonstrate a causal relation between exposure…”
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Characterization of histamine releasing factors in diisocyanate-induced occupational asthma by Lummus, Zana L., Alam, Rafeul, Bernstein, Jonathan A., Bernstein, David I.

“…Immunologic mechanisms contributing to diisocyanate-induced occupational asthma (OA) are poorly defined. There is a relatively low incidence of…”
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Occupational asthma caused by FD&C blue dye no. 2 by Miller, M E, Lummus, Z L, Bernstein, D I

“…We report the case of a 55-year-old male who experienced cough, dyspnea, wheezing, and nasal congestion immediately upon exposure to FD&C Blue Dye No. 2…”
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Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor [alpha] by Bernstein, David I, Kissling, Grace E, Khurana Hershey, Gurjit, Yucesoy, Berran, Johnson, Victor J, Cartier, André, Gautrin, Denyse, Sastre, Joaquin, Boulet, Louis-Philippe, Malo, Jean-Luc, Quirce, Santiago, Tarlo, Susan M, Langmeyer, Stacy, Luster, Michael I, Lummus, Zana L

“…Genotype or genotype combinations of IL4RA (I50V), IL13 (R110Q), and CD14 (C159T) SNPs P values OR (95% CI) for genotype among diisocyanate-exposed workers…”
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