Search Results - "Lummis, S.C.R."

Agonists and Antagonists Bind to an A-A Interface in the Heteromeric 5-HT3AB Receptor by Lochner, M., Lummis, S.C.R.

“…The 5-HT3 receptor is a member of the Cys-loop family of transmitter receptors. It can function as a homopentamer (5-HT3A-only subunits) or as a…”
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The transmembrane domain of the 5-HT3 receptor: its role in selectivity and gating by Lummis, S C R

“…The 5-HT3 (5-hydroxytryptamine) receptor is a typical member of the Cys-loop family of ligand-gated ion channels. No atomic resolution structures of these…”
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Characterisation of thymol effects on RDL receptors from the bee parasite Varroa destructor by Price, K.L., Lummis, S.C.R.

“…A major contributor to bee colony decline is infestation with its most devastating pest, the mite Varroa destructor. To control these mites, thymol is often…”
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Loop B Is a Major Structural Component of the 5-HT3 Receptor by Thompson, A.J., Lochner, M., Lummis, S.C.R.

“…The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence…”
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Binding of N-[propionyl-3H]propionylated alpha-bungarotoxin and L-[benzilic-4,4'-3H] quinuclidinyl benzilate to CNS extracts of the cockroach Periplaneta americana by Lummis, S C, Sattelle, D B

“…The nerve cord of the cockroach (Periplaneta americana) contains distinct saturable components of specific binding for the ligands…”
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Unbinding Pathways of an Agonist and an Antagonist from the 5-HT 3 Receptor by Thompson, A.J., Chau, P.-L., Chan, S.L., Lummis, S.C.R.

“…The binding sites of 5-HT 3 and other Cys-loop receptors have been extensively studied, but there are no data on the entry and exit routes of ligands for these…”
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Unbinding pathways of an agonist and an antagonist from the 5-HT3 receptor by Thompson, A J, Chau, P-L, Chan, S L, Lummis, S C R

“…The binding sites of 5-HT3 and other Cys-loop receptors have been extensively studied, but there are no data on the entry and exit routes of ligands for these…”
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Radioligand Binding and Photoaffinity Labelling Studies Show a Direct Interaction of Phenothiazines at 5-HT 3 Receptors by LUMMIS, S.C.R, BAKER, J

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Calcium changes induced by presynaptic 5-hydroxytryptamine-3 serotonin receptors on isolated terminals from various regions of the rat brain by Nayak, S.V., Rondé, P., Spier, A.D., Lummis, S.C.R., Nichols, R.A.

“…The serotonin 5-hydroxytryptamine-3 receptor is a ligand-gated ion channel that is distributed widely in the nervous system. Within the CNS, a significant…”
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Chlorpromazine and QX222 block 5-HT3 receptors in N1E-115 neuroblastoma cells by Sepúlveda, M I, Baker, J, Lummis, S C

“…The effects of chlorpromazine and the lidocaine derivative QX222, which block nicotinic acetylcholine receptors, were examined on 5-HT3 receptors in N1E-115…”
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Actions of nitromethylenes on an α-Bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor by Buckingham, S.D., Balk, M.l., Lummis, S.C.R., Jewess, P., Sattelle, D.B.

“…Nine nitromethylene analogues were tested for their actions on insect neuronal nicotinic acetylcholine receptors (nAChRs). Microelectrode recordings were used…”
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Kappa-bungarotoxin blocks an alpha-bungarotoxin-sensitive nicotinic receptor in the insect central nervous system by Pinnock, R D, Lummis, S C, Chiappinelli, V A, Sattelle, D B

“…Snake venom kappa-neurotoxins are selective antagonists of nicotinic acetylcholine responses in avian, murine and bovine neurons, and have been used as probes…”
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Gamma-aminobutyric acid-modulated benzodiazepine binding sites in bacteria by Lummis, S C, Nicoletti, G, Johnston, G A, Holan, G

“…Benzodiazepine binding sites, which were once considered to exist only in higher vertebrates, are here demonstrated in the bacteria E.coli. The bacterial…”
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Insect central nervous system gamma-aminobutyric acid by Lummis, S C, Sattelle, D B

“…Specific saturable binding of radiolabelled gamma-aminobutyric acid (GABA) has been demonstrated in central nervous system (CNS) extracts of the cockroach,…”
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Blocking actions of heptachlor at an insect central nervous system GABA receptor by Lummis, S. C. R., Buckingham, Steven D., Rauh, J. J., Sattelle, David B.

“…The actions of the polychlorocycloalkane insecticide heptachlor, and its epoxide metabolite, were examined on GABA receptors in insects and vertebrates…”
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Beta-adrenoceptors in human airway tissue: relationship between functional responsiveness and receptor number by Whicker, S D, Lummis, S C, Black, J L

“…Functional organ bath experiments and radiolabelled ligand binding studies were used to investigate the relationship between beta-adrenoceptor-mediated…”
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Actions of a series of bisquaternary compounds on nicotinic acetylcholine receptors in insects: ligand binding and electrophysiological studies by Lummis, S C, Buckingham, S D, Balk, M L, Holyoke, Jr, C W, Sattelle, D B

“…A series of bisquaternary ammoniums, with chain lengths of between 4-12 carbon atoms (C4-C12), have been tested for their ability to block…”
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The cross-linking reagent dimethyl suberimate modifies the target size of an insect nervous system nicotinic acetylcholine receptor by Lummis, S C, Ellory, J C, Sattelle, D B

“…Radiation inactivation and simple target theory were employed to determine the molecular weight of an insect CNS alpha-bungarotoxin binding component in the…”
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Molecular weight estimates of insect cholinergic receptors by radiation inactivation by Lummis, S C, Sattelle, D B, Ellory, J C

“…Molecular weight (MW) estimates for sites to which the radiolabelled cholinergic receptor probes alpha-bungarotoxin and N-methylscopolamine bind in CNS…”
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