Extracorporeal Circulatory Factors and Cerebral Functions in Operated Patients

Objective: to establish a relationship between the influence of extracorporeal circulation (EC) factors — its duration, mean blood pressure, and the magnitude of cerebral dysfunction. Subjects and methods. Thirty patients who had undergone above 120-min EC with surface (34—33°C) hypothermia of the b...

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Bibliographic Details
Published in:	Obshchai͡a︡ reanimatologii͡a Vol. 5; no. 2; p. 53
Main Authors:	Postnov, V. G., Karaskov, A. M., Lomivorotov, V. N., Zelman, V. L., Lumb, Ph
Format:	Journal Article
Language:	English
Published:	Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 20-04-2009
Online Access:	Get full text
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Summary:	Objective: to establish a relationship between the influence of extracorporeal circulation (EC) factors — its duration, mean blood pressure, and the magnitude of cerebral dysfunction. Subjects and methods. Thirty patients who had undergone above 120-min EC with surface (34—33°C) hypothermia of the body due to cardiosurgical intervention were examined by neurological and neuropsychological methods as described by A. R. Luriya. Results. Acute global brain ischemia (AGBI), as a consequence of negative EC factors, was shown to have impact on cerebral, specifically, higher psychic functions. There was a heterogeneous susceptibility of cerebral structures to AGBI, particularly the structures of the left hemisphere and cerebellum. Conclusion. The duration of perfusion is a determinant in the development of AGBI when extracorporeal circulation is applied. Arterial hypotensive episodes and critically low mean blood pressure are an important concomitant. Key words: extracorporeal (artificial) circulation, higher psychic functions, neurology, neuropsychology, neurodynamics, acute global brain ischemia.
ISSN:	1813-9779 2411-7110
DOI:	10.15360/1813-9779-2009-2-53