Search Results - "Lulu, Talal Ben"

Activation of the EGFR/PI3K/AKT pathway limits the efficacy of trametinib treatment in head and neck cancer by Novoplansky, Ofra, Shnerb, Avital B., Marripati, Divyasree, Jagadeeshan, Sankar, Abu Shareb, Raghda, Conde‐López, Cristina, Zorea, Jonathan, Prasad, Manu, Ben Lulu, Talal, Yegodayev, Ksenia M., Benafsha, Chen, Li, Yushi, Kong, Dexin, Kuo, Fengshen, Morris, Luc G. T., Kurth, Ina, Hess, Jochen, Elkabets, Moshe

“…Blocking the mitogen‐activated protein kinase (MAPK) pathway with the MEK1/2 inhibitor trametinib has produced promising results in patients with head and neck…”
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Mutated HRAS Activates YAP1-AXL Signaling to Drive Metastasis of Head and Neck Cancer by Jagadeeshan, Sankar, Prasad, Manu, Badarni, Mai, Ben-Lulu, Talal, Liju, Vijayasteltar Belsamma, Mathukkada, Sooraj, Saunders, Claire, Shnerb, Avital Beeri, Zorea, Jonathan, Yegodayev, Ksenia M, Wainer, Monica, Vtorov, Liza, Allon, Irit, Cohen, Ofir, Gausdal, Gro, Friedmann-Morvinski, Dinorah, Cheong, Sok Ching, Ho, Alan L, Rosenberg, Ari J, Kessler, Linda, Burrows, Francis, Kong, Dexin, Grandis, Jennifer R, Gutkind, J Silvio, Elkabets, Moshe

“…The survival rate for patients with head and neck cancer (HNC) diagnosed with cervical lymph node (cLN) or distant metastasis is low. Genomic alterations in…”
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A novel pan-PI3K inhibitor KTC1101 synergizes with anti-PD-1 therapy by targeting tumor suppression and immune activation by Peng, Xin, Huang, Xin, Lulu, Talal Ben, Jia, Wenqing, Zhang, Shaolu, Cohen, Limor, Huang, Shengfan, Fan, Jindian, Chen, Xi, Liu, Shanshan, Wang, Yongzhe, Wang, Kailin, Isoyama, Sho, Dan, Shingo, Wang, Feng, Zhang, Zhe, Elkabets, Moshe, Kong, Dexin

“…Phosphoinositide 3-kinases (PI3Ks) are critical regulators of diverse cellular functions and have emerged as promising targets in cancer therapy. Despite…”
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Dual inhibition of HERs and PD-1 counteract resistance in KRASG12C-mutant head and neck cancer by Novoplansky, Ofra, Jagadeeshan, Sankar, Prasad, Manu, Yegodayev, Ksenia M., Marripati, Divyasree, Shareb, Raghda Abu, Greenshpan, Yariv, Mathukkada, Sooraj, Ben-Lulu, Talal, Bhattacharya, Baisali, Porgador, Angel, Kong, Dexin, Brägelmann, Johannes, Gutkind, J. Silvio, Elkabets, Moshe

“…Abstract Background Basket clinical trials targeting the KRAS G12C -mutation in solid tumors have shown initial promise, including in orphan KRAS G12C head and…”
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