Search Results - "Lulla, Premal"

CAR T cells and autologous transplantation can coexist for DLBCL by Lulla, Premal D.

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Emerging Challenges to Cellular Therapy of Cancer by Lulla, Premal D., Brenner, Malcolm

“…Cellular immunotherapy of cancer in the form of chimeric antigen receptor-modified T-cell therapy has become a standard treatment for lymphoid and more…”
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Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma by Ramos, Carlos A, Grover, Natalie S, Beaven, Anne W, Lulla, Premal D, Wu, Meng-Fen, Ivanova, Anastasia, Wang, Tao, Shea, Thomas C, Rooney, Cliona M, Dittus, Christopher, Park, Steven I, Gee, Adrian P, Eldridge, Paul W, McKay, Kathryn L, Mehta, Birju, Cheng, Catherine J, Buchanan, Faith B, Grilley, Bambi J, Morrison, Kaitlin, Brenner, Malcolm K, Serody, Jonathan S, Dotti, Gianpietro, Heslop, Helen E, Savoldo, Barbara

“…Chimeric antigen receptor (CAR) T-cell therapy of B-cell malignancies has proved to be effective. We show how the same approach of CAR T cells specific for…”
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COVID-specific T's may offset therapeutically endangered B's by Hill, LaQuisa C., Lulla, Premal D.

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Myelodysplastic syndrome and immunotherapy novel to next in-line treatments by Linder, Katherine, Lulla, Premal

“…Patients with Myelodysplastic syndromes (MDS) have few therapy options for sustainable responses in the frontline setting, and even less after hypomethylating…”
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Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant by Lulla, Premal D., Naik, Swati, Vasileiou, Spyridoula, Tzannou, Ifigeneia, Watanabe, Ayumi, Kuvalekar, Manik, Lulla, Suhasini, Carrum, George, Ramos, Carlos A., Kamble, Rammurti, Hill, LaQuisa, Randhawa, Jasleen, Gottschalk, Stephen, Krance, Robert, Wang, Tao, Wu, Mengfen, Robertson, Catherine, Gee, Adrian P., Chung, Betty, Grilley, Bambi, Brenner, Malcolm K., Heslop, Helen E., Vera, Juan F., Leen, Ann M.

“…Relapse after allogeneic hematopoietic stem cell transplantation (HCT) is the leading cause of death in patients with acute myeloid leukemia (AML) or…”
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Targeting IDH2R140Q and other neoantigens in acute myeloid leukemia by Leung, Wingchi K., Torres Chavez, Alejandro G., French-Kim, Matthew, Shafer, Paul, Mamonkin, Maksim, Hill, LaQuisa C., Kuvalekar, Manik, Velazquez, Yovana, Watanabe, Ayumi, Watanabe, Norihiro, Hoyos, Valentina, Lulla, Premal, Leen, Ann M.

“…•Neoantigens arising from recurrent AML mutations are immunogenic and represent novel immunotherapeutic targets.•IDH2R140Q-specific T cells can selectively…”
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Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs by Steffin, David H M, Muhsen, Ibrahim N, Hill, LaQuisa C, Ramos, Carlos A, Ahmed, Nabil, Hegde, Meenakshi, Wang, Tao, Wu, Mengfen, Gottschalk, Stephen, Whittle, Sarah B, Lulla, Premal D, Mamonkin, Maksim, Omer, Bilal, Rouce, Rayne H, Heczey, Andras, Metelitsa, Leonid S, Grilley, Bambi J, Robertson, Catherine, Torrano, Virginia, Lapteva, Natalia, Gee, Adrian P, Rooney, Cliona M, Brenner, Malcolm K, Heslop, Helen E

“…Subsequent malignancies are well-documented complications in long-term follow-up of cancer patients. Recently, genetically modified immune effector (IE) cells…”
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T-Cell Therapy for Lymphoma Using Nonengineered Multiantigen-Targeted T Cells Is Safe and Produces Durable Clinical Effects by Vasileiou, Spyridoula, Lulla, Premal D, Tzannou, Ifigeneia, Watanabe, Ayumi, Kuvalekar, Manik, Callejas, Wendy L, Bilgi, Mrinalini, Wang, Tao, Wu, Mengfen J, Kamble, Rammurti, Ramos, Carlos A, Rouce, Rayne H, Zeng, Zihua, Gee, Adrian P, Grilley, Bambi J, Vera, Juan F, Bollard, Catherine M, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M, Leen, Ann M, Carrum, George

“…Patients with relapsed lymphomas often fail salvage therapies including high-dose chemotherapy and mono-antigen-specific T-cell therapies, highlighting the…”
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Approved CAR-T therapies have reproducible efficacy and safety in clinical practice by Goyco Vera, Daniel, Waghela, Hiral, Nuh, Mohamed, Pan, Jonathan, Lulla, Premal

“…CAR-T cell therapy has established itself as a highly effective treatment for hematological malignancies. There are currently six commercial CAR-T products…”
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Donor-derived multiple leukemia antigen–specific T-cell therapy to prevent relapse after transplant in patients with ALL by Naik, Swati, Vasileiou, Spyridoula, Tzannou, Ifigeneia, Kuvalekar, Manik, Watanabe, Ayumi, Robertson, Catherine, Lapteva, Natalia, Tao, Wang, Wu, Mengfen, Grilley, Bambi, Carrum, George, Kamble, Rammurti T., Hill, LaQuisa, Krance, Robert A., Martinez, Caridad, Tewari, Priti, Omer, Bilal, Gottschalk, Stephen, Heslop, Helen E., Brenner, Malcom K., Rooney, Cliona M., Vera, Juan F., Leen, Ann M., Lulla, Premal D.

“…Hematopoietic stem cell transplant (HSCT) is a curative option for patients with high-risk acute lymphoblastic leukemia (ALL), but relapse remains a major…”
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Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients by Vasileiou, Spyridoula, Hill, LaQuisa, Kuvalekar, Manik, Workineh, Aster G, Watanabe, Ayumi, Velazquez, Yovana, Lulla, Suhasini, Mooney, Kimberly, Lapteva, Natalia, Grilley, Bambi J, Heslop, Helen E, Rooney, Cliona M, Brenner, Malcolm K, Eagar, Todd N, Carrum, George, Grimes, Kevin A, Leen, Ann M, Lulla, Premal

“…Defects in T-cell immunity to SARS-CoV-2 have been linked to an increased risk of severe COVID-19 (even after vaccination), persistent viral shedding and the…”
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Adoptive Cell Therapy for Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia by Lulla, Premal D, Mamonkin, Maksim, Brenner, Malcolm K

“…Refractory and relapsed acute myeloid leukemia (AML) and T-lineage leukemia have poor prognosis and limited therapeutic options. Adoptive cellular…”
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CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation by Bajgain, Pradip, Tawinwung, Supannikar, D'Elia, Lindsey, Sukumaran, Sujita, Watanabe, Norihiro, Hoyos, Valentina, Lulla, Premal, Brenner, Malcolm K, Leen, Ann M, Vera, Juan F

“…The adoptive transfer of T cells redirected to tumor via chimeric antigen receptors (CARs) has produced clinical benefits for the treatment of hematologic…”
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Rapid generation of multivirus-specific T lymphocytes for the prevention and treatment of respiratory viral infections by Vasileiou, Spyridoula, Turney, Anne M, Kuvalekar, Manik, Mukhi, Shivani S, Watanabe, Ayumi, Lulla, Premal, Ramos, Carlos A, Naik, Swati, Vera, Juan F, Tzannou, Ifigeneia, Leen, Ann M

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Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy by Kapadia, Chiraag D., Rosas, Gerardo, Thakkar, Sachin G., Wu, Mengfen, Torrano, Virginia, Wang, Tao, Grilley, Bambi J., Heslop, Helen E., Ramos, Carlos A., Goodell, Margaret A., Lulla, Premal D.

“…Chimeric antigen receptor (CAR) T-cells are an emerging therapy for refractory lymphomas. Clonal hematopoiesis (CH), the preferential outgrowth of mutated bone…”
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Rituximab as adjunctive therapy to BEAM conditioning for autologous stem cell transplantation in Hodgkin lymphoma by Friend, Brian D., Muhsen, Ibrahim N., Patel, Shreeya, Hill, LaQuisa C., Lulla, Premal, Ramos, Carlos A., Pingali, S. Ravi, Kamble, Rammurti T., John, Tami D., Salem, Baheyeldin, Bhar, Saleh, Doherty, Erin E., Craddock, John, Sasa, Ghadir, Wu, Mengfen, Wang, Tao, Martinez, Caridad, Krance, Robert A., Heslop, Helen E., Carrum, George

“…While high-dose chemotherapy followed by autologous stem cell transplantation (ASCT) leads to improved disease-free survival (DFS) for children and adults with…”
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Immunologic Profiling of Human Metapneumovirus for the Development of Targeted Immunotherapy by Tzannou, Ifigeneia, Nicholas, Sarah K., Lulla, Premal, Aguayo-Hiraldo, Paibel I., Misra, Anisha, Martinez, Caridad A., Machado, Annette A., Orange, Jordan S., Piedra, Pedro A., Vera, Juan F., Leen, Ann M.

“…Human metapneumovirus (hMPV) is a respiratory virus detected in ≥9% of allogeneic hematopoietic stem cell transplant (HSCT) recipients, in whom it can cause…”
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The use of chimeric antigen receptor T cells in patients with non-Hodgkin lymphoma by Lulla, Premal D, Hill, LaQuisa C, Ramos, Carlos A, Heslop, Helen E

“…Resistance to conventional lines of therapy develops in approximately 20% of all patients with lymphoma. These patients have a dismal prognosis, with an…”
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Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer by Hoyos, Valentina, Vasileiou, Spyridoula, Kuvalekar, Manik, Watanabe, Ayumi, Tzannou, Ifigeneia, Velazquez, Yovana, French-Kim, Matthew, Leung, Wingchi, Lulla, Suhasini, Robertson, Catherine, Foreman, Claudette, Wang, Tao, Bulsara, Shaun, Lapteva, Natalia, Grilley, Bambi, Ellis, Matthew, Osborne, Charles Kent, Coscio, Angela, Nangia, Julie, Heslop, Helen E., Rooney, Cliona M., Vera, Juan F., Lulla, Premal, Rimawi, Mothaffar, Leen, Ann M.

“…Purpose: Adoptively transferred, ex vivo expanded multi-antigen-targeted T cells (multiTAA-T) represent a new, potentially effective, and nontoxic therapeutic…”
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