Search Results - "Luke, A. K."

Effect of serum sample storage temperature on metabolomic and proteomic biomarkers by Valo, Erkka, Colombo, Marco, Sandholm, Niina, McGurnaghan, Stuart J., Blackbourn, Luke A. K., Dunger, David B., McKeigue, Paul M., Forsblom, Carol, Groop, Per-Henrik, Colhoun, Helen M., Turner, Charles, Dalton, R. Neil

“…Prospective biomarker studies can be used to identify biomarkers predictive of disease onset. However, if serum biomarkers are measured years after their…”
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Comparison of serum and urinary biomarker panels with albumin/creatinine ratio in the prediction of renal function decline in type 1 diabetes by Colombo, Marco, McGurnaghan, Stuart J., Blackbourn, Luke A. K., Dalton, R. Neil, Dunger, David, Bell, Samira, Petrie, John R., Green, Fiona, MacRury, Sandra, McKnight, John A., Chalmers, John, Collier, Andrew, McKeigue, Paul M., Colhoun, Helen M.

“…Aims/hypothesis We examined whether candidate biomarkers in serum or urine can improve the prediction of renal disease progression in type 1 diabetes beyond…”
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Marked improvements in glycaemic outcomes following insulin pump therapy initiation in people with type 1 diabetes: a nationwide observational study in Scotland by Jeyam, Anita, Gibb, Fraser W., McKnight, John A., Kennon, Brian, O’Reilly, Joseph E., Caparrotta, Thomas M., Höhn, Andreas, McGurnaghan, Stuart J., Blackbourn, Luke A. K., Hatam, Sara, McCrimmon, Rory J., Leese, Graham, Lindsay, Robert S., Petrie, John, Chalmers, John, Philip, Sam, Wild, Sarah H., Sattar, Naveed, McKeigue, Paul M., Colhoun, Helen M.

“…Aims/hypothesis Our aim was to assess the use of continuous subcutaneous insulin infusion (CSII) in people with type 1 diabetes in Scotland and its association…”
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Development and validation of a cardiovascular risk prediction model in type 1 diabetes by McGurnaghan, Stuart J., McKeigue, Paul M., Read, Stephanie H., Franzen, Stefan, Svensson, Ann-Marie, Colombo, Marco, Livingstone, Shona, Farran, Bassam, Caparrotta, Thomas M., Blackbourn, Luke A. K., Mellor, Joseph, Thoma, Ioanna, Sattar, Naveed, Wild, Sarah H., Gudbjörnsdottir, Soffia, Colhoun, Helen M.

“…Aims/hypothesis We aimed to report current rates of CVD in type 1 diabetes and to develop a CVD risk prediction tool for type 1 diabetes. Methods A cohort of…”
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Flash monitor initiation is associated with improvements in HbA1c levels and DKA rates among people with type 1 diabetes in Scotland: a retrospective nationwide observational study by Jeyam, Anita, Gibb, Fraser W., McKnight, John A., O’Reilly, Joseph E., Caparrotta, Thomas M., Höhn, Andreas, McGurnaghan, Stuart J., Blackbourn, Luke A. K., Hatam, Sara, Kennon, Brian, McCrimmon, Rory J., Leese, Graham, Philip, Sam, Sattar, Naveed, McKeigue, Paul M., Colhoun, Helen M.

“…Aims/hypothesis We assessed the real-world effect of flash monitor (FM) usage on HbA 1c levels and diabetic ketoacidosis (DKA) and severe hospitalised…”
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The Kondo Effect in the Presence of Ferromagnetism by Pasupathy, Abhay N., Bialczak, Radoslaw C., Martinek, Jan, Grose, Jacob E., Luke A. K. Donev, McEuen, Paul L., Ralph, Daniel C.

“…We measured Kondo-assisted tunneling via C60molecules in contact with ferromagnetic nickel electrodes. Kondo correlations persisted despite the presence of…”
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Large socioeconomic gap in period life expectancy and life years spent with complications of diabetes in the Scottish population with type 1 diabetes, 2013-2018 by Höhn, Andreas, McGurnaghan, Stuart J, Caparrotta, Thomas M, Jeyam, Anita, O'Reilly, Joseph E, Blackbourn, Luke A K, Hatam, Sara, Dudel, Christian, Seaman, Rosie J, Mellor, Joseph, Sattar, Naveed, McCrimmon, Rory J, Kennon, Brian, Petrie, John R, Wild, Sarah, McKeigue, Paul M, Colhoun, Helen M

“…We report the first study to estimate the socioeconomic gap in period life expectancy (LE) and life years spent with and without complications in a national…”
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N-Glycan Profile and Kidney Disease in Type 1 Diabetes by Bermingham, Mairead L, Colombo, Marco, McGurnaghan, Stuart J, Blackbourn, Luke A K, Vučković, Frano, Pučić Baković, Maja, Trbojević-Akmačić, Irena, Lauc, Gordan, Agakov, Felix, Agakova, Anna S, Hayward, Caroline, Klarić, Lucija, Palmer, Colin N A, Petrie, John R, Chalmers, John, Collier, Andrew, Green, Fiona, Lindsay, Robert S, Macrury, Sandra, McKnight, John A, Patrick, Alan W, Thekkepat, Sandeep, Gornik, Olga, McKeigue, Paul M, Colhoun, Helen M

“…Poorer glycemic control in type 1 diabetes may alter N-glycosylation patterns on circulating glycoproteins, and these alterations may be linked with diabetic…”
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Incidence of Type 1 Diabetes in Children Has Fallen to Pre-COVID-19 Pandemic Levels: A Population-Wide Analysis From Scotland by Berthon, William, McGurnaghan, Stuart J, Blackbourn, Luke A K, Bath, Louise E, McAllister, David A, Stockton, Diane, Wild, Sarah H, McKeigue, Paul M, Colhoun, Helen M

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The association of polypharmacy and high-risk drug classes with adverse health outcomes in the Scottish population with type 1 diabetes by Höhn, Andreas, Jeyam, Anita, Caparrotta, Thomas M., McGurnaghan, Stuart J., O’Reilly, Joseph E., Blackbourn, Luke A. K., McCrimmon, Rory J., Leese, Graham P., McKnight, John A., Kennon, Brian, Lindsay, Robert S., Sattar, Naveed, Wild, Sarah H., McKeigue, Paul M., Colhoun, Helen M.

“…Aims/hypothesis The aim of this work was to map the number of prescribed drugs over age, sex and area-based socioeconomic deprivation, and to examine the…”
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Diabetic Neuropathy Is a Substantial Burden in People With Type 1 Diabetes and Is Strongly Associated With Socioeconomic Disadvantage: A Population-Representative Study From Scotland by Jeyam, Anita, McGurnaghan, Stuart J, Blackbourn, Luke A K, McKnight, John M, Green, Fiona, Collier, Andrew, McKeigue, Paul M, Colhoun, Helen M

“…To assess the contemporaneous prevalence of diabetic peripheral neuropathy (DPN) in people with type 1 diabetes (T1D) in Scotland and study its cross-sectional…”
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Time trends in deaths before age 50 years in people with type 1 diabetes: a nationwide analysis from Scotland 2004–2017 by O’Reilly, Joseph E., Blackbourn, Luke A. K., Caparrotta, Thomas M., Jeyam, Anita, Kennon, Brian, Leese, Graham P., Lindsay, Robert S., McCrimmon, Rory J., McGurnaghan, Stuart J., McKeigue, Paul M., McKnight, John A., Petrie, John R., Philip, Sam, Sattar, Naveed, Wild, Sarah H., Colhoun, Helen M.

“…Aims/hypothesis We aimed to examine whether crude mortality and mortality relative to the general population below 50 years of age have improved in recent…”
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Cohort profile: the Scottish Diabetes Research Network national diabetes cohort – a population-based cohort of people with diabetes in Scotland by McGurnaghan, Stuart J., Blackbourn, Luke A. K., Caparrotta, Thomas M., Mellor, Joseph, Barnett, Anna, Collier, Andy, Sattar, Naveed, McKnight, John, Petrie, John, Philip, Sam, Lindsay, Robert, Hughes, Katherine, McAllister, David, Leese, Graham P, Pearson, Ewan R, Wild, Sarah, McKeigue, Paul M, Colhoun, Helen M

“…PurposeThe Scottish Diabetes Research Network (SDRN)-diabetes research platform was established to combine disparate electronic health record data into…”
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Prescribing Paradigm Shift? Applying the 2019 European Society of Cardiology-Led Guidelines on Diabetes, Prediabetes, and Cardiovascular Disease to Assess Eligibility for Sodium-Glucose Cotransporter 2 Inhibitors or Glucagon-Like Peptide 1 Receptor Agonists as First-Line Monotherapy (or Add-on to Metformin Monotherapy) in Type 2 Diabetes in Scotland by Caparrotta, Thomas M, Blackbourn, Luke A K, McGurnaghan, Stuart J, Chalmers, John, Lindsay, Robert, McCrimmon, Rory, McKnight, John, Wild, Sarah, Petrie, John R, Philip, Sam, McKeigue, Paul M, Webb, David J, Sattar, Naveed, Colhoun, Helen M

“…In 2019, the European Society of Cardiology led and released new guidelines for diabetes cardiovascular risk management, reflecting recent evidence of…”
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Rising Rates and Widening Socioeconomic Disparities in Diabetic Ketoacidosis in Type 1 Diabetes in Scotland: A Nationwide Retrospective Cohort Observational Study by O’Reilly, Joseph E., Jeyam, Anita, Caparrotta, Thomas M., Mellor, Joseph, Hohn, Andreas, McKeigue, Paul M., McGurnaghan, Stuart J., Blackbourn, Luke A.K., McCrimmon, Rory, Wild, Sarah H., Petrie, John R., McKnight, John A., Kennon, Brian, Chalmers, John, Phillip, Sam, Leese, Graham, Lindsay, Robert S., Sattar, Naveed, Gibb, Fraser W., Colhoun, Helen M.

“…OBJECTIVE Whether advances in the management of type 1 diabetes are reducing rates of diabetic ketoacidosis (DKA) is unclear. We investigated time trends in…”
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Calibrating a network meta-analysis of diabetes trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population: a systematic review protocol by Butterly, Elaine, Wei, Lili, Adler, Amanda I, Almazam, Saleh A M, Alsallumi, Khalid, Blackbourn, Luke A K, Dias, Sofia, Hanlon, Peter, Hughes, Katherine, Lewsey, Jim, Lindsay, Robert, McGurnaghan, Stuart, Petrie, John, Phillippo, David, Sattar, Naveed, Tomlinson, Laurie A, Welton, Nicky, Wild, Sarah, McAllister, David

“…IntroductionParticipants in randomised controlled trials (trials) are generally younger and healthier than many individuals encountered in clinical practice…”
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Imaging the electrical conductance of individual carbon nanotubes with photothermal current microscopy by Park, Jiwoong, Tsen, Adam W, Donev, Luke A. K, Kurt, Huseyin, Herman, Lihong H

“…The one-dimensional structure of carbon nanotubes 1 leads to a variety of remarkable optical 2 and electrical 3 properties that could be used to develop novel…”
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Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland by McGurnaghan, Stuart J, Weir, Amanda, Bishop, Jen, Kennedy, Sharon, Blackbourn, Luke A K, McAllister, David A, Hutchinson, Sharon, Caparrotta, Thomas M, Mellor, Joseph, Jeyam, Anita, O'Reilly, Joseph E, Wild, Sarah H, Hatam, Sara, Höhn, Andreas, Colombo, Marco, Robertson, Chris, Lone, Nazir, Murray, Janet, Butterly, Elaine, Petrie, John, Kennon, Brian, McCrimmon, Rory, Lindsay, Robert, Pearson, Ewan, Sattar, Naveed, McKnight, John, Philip, Sam, Collier, Andrew, McMenamin, Jim, Smith-Palmer, Alison, Goldberg, David, McKeigue, Paul M, Colhoun, Helen M, Whettlock, Alice, McLeod, Allan, Gasiorowski, Andrew, Merrick, Andrew, McAuley, Andy, Went, April, Purdie, Calum, Fischbacher, Colin, Ramsey, Colin, Bailey, David, Henderson, David, McDonald, Eisin, Drennan, Genna, Gowans, Graeme, Reid, Graeme, Murdoch, Heather, Carruthers, Jade, Murray, Josie, Heatlie, Karen, Donaldson, Lorraine, Paton, Martin, Reid, Martin, Llano, Melissa, Murphy-Hall, Michelle, Hall, Ross, Cameron, Ross, Brownlie, Susan, Gaffney, Adam, Milne, Aynsley, Sullivan, Christopher, McArdle, Edward, Glass, Elaine, Young, Johanna, Malcolm, William, McCoubrey, Jodie

“…We aimed to ascertain the cumulative risk of fatal or critical care unit-treated COVID-19 in people with diabetes and compare it with that of people without…”
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Biomarker panels associated with progression of renal disease in type 1 diabetes by Colombo, Marco, Valo, Erkka, McGurnaghan, Stuart J., Sandholm, Niina, Blackbourn, Luke A. K., Dalton, R. Neil, Dunger, David, Groop, Per-Henrik, McKeigue, Paul M., Forsblom, Carol, Colhoun, Helen M.

“…Aims/hypothesis We aimed to identify a sparse panel of biomarkers for improving the prediction of renal disease progression in type 1 diabetes. Methods We…”
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Impact of COVID-19 and Non-COVID-19 Hospitalized Pneumonia on Longer-Term Cardiovascular Mortality in People With Type 2 Diabetes: A Nationwide Prospective Cohort Study From Scotland by McGurnaghan, Stuart J, McKeigue, Paul M, Blackbourn, Luke A K, Mellor, Joseph, Caparrotta, Thomas M, Sattar, Naveed, Kennon, Brian, McAllister, David, Wild, Sarah H, Colhoun, Helen M

“…In this study we examine whether hospitalized coronavirus disease 2019 (COVID-19) pneumonia increases long-term cardiovascular mortality more than other…”
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