Search Results - "Lukacs, Janet L."

Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease by Sawyer, Jeffrey R., Tian, Erming, Heuck, Christoph J., Epstein, Joshua, Johann, Donald J., Swanson, Charles M., Lukacs, Janet L., Johnson, Marian, Binz, Regina, Boast, Angela, Sammartino, Gael, Usmani, Saad, Zangari, Maurizio, Waheed, Sarah, van Rhee, Frits, Barlogie, Bart

“…Multiple myeloma (MM) is a B-cell malignancy driven in part by increasing copy number alterations (CNAs) during disease progression. Prognostically significant…”
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Genomic instability in multiple myeloma: Evidence for jumping segmental duplications of chromosome arm 1q by Sawyer, Jeffrey R., Tricot, Guido, Lukacs, Janet L., Binz, Regina Lichti, Tian, Erming, Barlogie, Bart, Shaughnessy Jr, John

“…Multiple myeloma (MM) is a malignant plasma cell disorder characterized by complex karyotypes and chromosome 1 instability at the cytogenetic level. Chromosome…”
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Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma by Sawyer, Jeffrey R., Tian, Erming, Heuck, Christoph J., Johann, Donald J., Epstein, Joshua, Swanson, Charles M., Lukacs, Janet L., Binz, Regina Lichti, Johnson, Marian, Sammartino, Gael, Zangari, Maurizio, Davies, Faith E., van Rhee, Frits, Morgan, Gareth J., Barlogie, Bart

“…Multiple myeloma is a B-cell malignancy stratified in part by cytogenetic abnormalities, including the high-risk copy number aberrations (CNAs) of +1q21 and…”
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Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma by Sawyer, Jeffrey R., Lukacs, Janet L., Thomas, Edward L., Swanson, Charles M., Goosen, Linda S., Sammartino, Gael, Gilliland, John C., Munshi, Nikhil C., Tricot, Guido, Shaughnessy, John D., Barlogie, Bart

“…Multicolour spectral karyotyping (SKY) was performed on primary tumour specimens from 100 patients with multiple myeloma (MM) that showed complex clonal…”
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An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome by Sawyer, Jeffrey R., Tian, Erming, Walker, Brian A., Wardell, Christopher, Lukacs, Janet L., Sammartino, Gael, Bailey, Clyde, Schinke, Carolina D., Thanendrarajan, Sharmilan, Davies, Faith E., Morgan, Gareth J., Barlogie, Bart, Zangari, Maurizio, van Rhee, Frits

“…Patients with multiple myeloma (MM) accumulate adverse copy number aberrations (CNAs), gains of 1q21, and 17p deletions during disease progression. A subset of…”
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Cytogenetic distinction among benign fibro-osseous lesions of bone in children and adolescents: value of karyotypic findings in differential diagnosis by Parham, David M, Bridge, Julia A, Lukacs, Janet L, Ding, Yiling, Tryka, A Francine, Sawyer, Jeffrey R

“…Benign fibro-osseous lesions of bone (BFOL) comprise a group of clinically distinct entities with significant histologic overlap and often occur in children…”
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An Acquired High-Risk Chromosome Instability Phenotype in Multiple Myeloma: Jumping 1q Syndrome by Sawyer, Jeffery R., Tian, Erming, Walker, Brian A, Wardell, Christopher P., Epstein, Joshua, Lukacs, Janet L, Sammartino, Gael M., Bailey, Clyde, Schinke, Carolina D., Thanendrarajan, Sharmilan, Zangari, Maurizio, Davies, Faith E., van Rhee, Frits, Morgan, Gareth

“…Introduction Chromosome instability (CIN) is a driver of copy number aberrations (CNAs) in cancer, and is a major factor leading to tumor heterogeneity and…”
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Factors in nurse practitioner role adjustment by Lukacs, J L

“…In a survey to determine the existence, extent and nature of an adjustment for nurse practitioners as they assumed responsibilities associated with the NP…”
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Chromosome 1q12 Instability Drives Both 1q21 Amplification and Arm-Length Deletions in Multiple Myeloma by Sawyer, Jeffery R., Tian, Erming, Walker, Brian A, Swanson, Charles M., Lukacs, Janet L, Sammartino, Gael M., Bailey, Clyde, Thanendrarajan, Sharmilan, Schinke, Carolina D., Zangari, Maurizio, van Rhee, Frits, Davies, Faith E., Morgan, Gareth J.

“…Introduction Chromosome instability is a driver of copy number aberrations (CNAs) in cancer, and is a factor leading to tumor heterogeneity and resistance to…”
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Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma by Sawyer, J R, Tian, E, Shaughnessy Jr, J D, Epstein, J, Swanson, C M, Stangeby, C, Hale, C L, Parr, L, Lynn, M, Sammartino, G, Lukacs, J L, Stein, C, Bailey, C, Zangari, M, Davies, F E, Van Rhee, F, Barlogie, B, Morgan, G J

“…Hyperhaploid clones (24–34 chromosomes) were identified in 33 patients with multiple myeloma (MM), demonstrating a novel numerical cytogenetic subgroup…”
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Concurrent Amplification of MYC and 1q21 in Multiple Myeloma: Focal and Segmental Jumping Translocations of MYC by Sawyer, Jeffery, Tian, Erming, Walker, Brian A, Weinhold, Niels, Swanson, Charles, Lukacs, Janet L, Binz, Regina, Sammartino, Gael, Thanendrarajan, Sharmilan, Schinke, Carolina, Zangari, Maurizio, Davies, Faith E, van Rhee, Frits, Morgan, Gareth J

“…Introduction Multiple myeloma (MM) is characterized by an accumulation of secondary chromosome aberrations which lead to cytogenetically heterogeneous…”
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Identification of New Nonrandom Translocations in Multiple Myeloma With Multicolor Spectral Karyotyping by Sawyer, Jeffrey R., Lukacs, Janet L., Munshi, Nikhil, Desikan, K. Raman, Singhal, Seema, Mehta, Jayesh, Siegel, David, Shaughnessy, John, Barlogie, Bart

“…Multicolor spectral karyotyping (SKY) was performed on bone marrow samples from 50 patients with multiple myeloma (MM) in anticipation of discovering new…”
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Strategic planning in hospitals. Applications for nurse executives by Lukacs, J L

“…Strategic planning has been used in business to strengthen competitive position and improve overall performance. This method of analysis also offers nurse…”
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Recurring breakpoints of 1p13∼p22 in osteochondroma by Sawyer, Jeffrey R., Thomas, Edward L., Lukacs, Janet L., Swanson, Charles M., Ding, Yiling, Parham, David M., Thomas, James R., Nicholas, Richard W.

“…Cytogenetic studies of osteochondromas are scarce but have previously shown recurring clonal aberrations involving chromosome 8. We have studied a series of…”
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Telomeric fusion as a mechanism for the loss of 1p in meningioma by Sawyer, Jeffrey R., Husain, Muhammad, Lukacs, Janet L., Stangeby, Colin, Binz, Regina Lichti, Al-Mefty, Ossama

“…Characteristic cytogenetic aberrations are found in the various histopathological designations of meningioma. These aberrations range from the loss of 22q in…”
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Evidence of an association between 6q13‐21 chromosome aberrations and locally aggressive behavior in patients with cartilage tumors by Sawyer, Jeffrey R., Swanson, Charles M., Lukacs, Janet L., Nicholas, Richard W., North, Paula E., Thomas, James R.

“…BACKGROUND The finding of a cytogenetic‐pathologic correlation between complex karyotypes and high grade cartilaginous tumors has been reported. However, few…”
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Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping by SAWYER, J. R, LUKACS, J. L, MUNSHI, N, DESIKAN, K. R, SINGHAL, S, MEHTA, J, SIEGEL, D, SHAUGHNESSY, J, BARLOGIE, B

“…Multicolor spectral karyotyping (SKY) was performed on bone marrow samples from 50 patients with multiple myeloma (MM) in anticipation of discovering new…”
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Recurring breakpoints of 1p13 approximately p22 in osteochondroma by Sawyer, Jeffrey R, Thomas, Edward L, Lukacs, Janet L, Swanson, Charles M, Ding, Yiling, Parham, David M, Thomas, James R, Nicholas, Richard W

“…Cytogenetic studies of osteochondromas are scarce but have previously shown recurring clonal aberrations involving chromosome 8. We have studied a series of…”
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Sub-band deletion of 7q36.3 in a patient with ring chromosome 7: Association with holoprosencephaly by Sawyer, Jeffrey R., Lukacs, Janet L., Hassed, Susan J., Arnold, Georgianne L., Mitchell, Heather F., Muenke, Maximilian

“…We report on a patient with ring chromosome 7 analyzed by both high‐resolution mid‐prophase G‐banding and fluorescence in situ hybridization (FISH) resolving a…”
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Telomeric fusion and chromosome instability in multiple tissues of a patient with mosaic Ullrich-Turner syndrome by Sawyer, Jeffrey R., Swanson, Charles M., Lukacs, Janet L., Hassed, Susan J., Curtis, Mary A., North, Paula E., Kozlowski, Karen J., Pihoker, Catherine

“…We describe the cytogenetic evolution of multiple cell lines in the gonadal tissue of a 10‐year‐old girl with mosaic Ullrich‐Turner syndrome (UTS) involving…”
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