Search Results - "Lukacova, Nadezda"
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Activation of Neuroprotective Microglia and Astrocytes at the Lesion Site and in the Adjacent Segments Is Crucial for Spontaneous Locomotor Recovery after Spinal Cord Injury
Published in Cells (Basel, Switzerland) (30-07-2021)“…Microglia and astrocytes play an important role in the regulation of immune responses under various pathological conditions. To detect environmental cues…”
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Glial-Neuronal Interactions in Pathogenesis and Treatment of Spinal Cord Injury
Published in International journal of molecular sciences (17-12-2021)“…Traumatic spinal cord injury (SCI) elicits an acute inflammatory response which comprises numerous cell populations. It is driven by the immediate response of…”
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Activation of Three Major Signaling Pathways After Endurance Training and Spinal Cord Injury
Published in Molecular neurobiology (01-02-2022)“…We aimed to investigate the effects of endurance training on expression of growth factors (GFs) and stimulation of neurotrophin-dependent signaling pathways…”
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Impact of Endurance Training on Regeneration of Axons, Glial Cells, and Inhibitory Neurons after Spinal Cord Injury: A Link between Functional Outcome and Regeneration Potential within the Lesion Site and in Adjacent Spinal Cord Tissue
Published in International journal of molecular sciences (11-05-2023)“…Endurance training prior to spinal cord injury (SCI) has a beneficial effect on the activation of signaling pathways responsible for survival, neuroplasticity,…”
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Epidural oscillating field stimulation increases axonal regenerative capacity and myelination after spinal cord trauma
Published in Neural regeneration research (01-12-2022)“…Oscillating field stimulation (OFS) with regular alterations in the polarity of electric current is a unique, experimental approach to stimulate, support, and…”
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A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome
Published in International journal of molecular sciences (07-04-2018)“…The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol…”
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Is Innervation of the Neuromuscular Junction at the Diaphragm Modulated by sGC/cGMP Signaling?
Published in Frontiers in physiology (23-06-2020)“…We previously reported NO/sGC signaling in the upper respiratory pathway, receiving input from the respiratory neurons of the brainstem to phrenic motoneurons…”
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The impact of short-lasting repeated vibrations on retrograde axonal transport, the expression of CGRP and parvalbumin in lower lumbar dorsal root ganglia
Published in Brain research (17-06-2011)“…Abstract A prolonged exposure to vibration stimuli triggers pathological changes with many later manifested symptoms. Early vibration-induced changes are still…”
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Thoracic 9 Spinal Transection-Induced Model of Muscle Spasticity in the Rat: A Systematic Electrophysiological and Histopathological Characterization
Published in PloS one (29-12-2015)“…The development of spinal hyper-reflexia as part of the spasticity syndrome represents one of the major complications associated with chronic spinal traumatic…”
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THE EFFECT OF SUBPIAL DELIVERY OF CHONDROITINASE ABC ON REGULATING PI3K/AKT SIGNALING PATHWAY AFTER SCI
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Baclofen or nNOS inhibitor affect molecular and behavioral alterations evoked by traumatic spinal cord injury in rat spinal cord
Published in The spine journal (01-06-2015)“…Abstract Background context The loss of descending control after spinal cord injury (SCI) and incessant stimulation of Ia monosynaptic pathway, carrying…”
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Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: Effect on spinally grafted human neural precursor survival
Published in Experimental neurology (01-10-2013)“…Achievement of effective, safe and long-term immunosuppression represents one of the challenges in experimental allogeneic and xenogeneic cell and organ…”
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Assessment of motor recovery and MRI correlates in a porcine spinal cord injury model
Published in Acta veterinaria Brno (08-12-2014)“…The study concentrated on behavioral and magnetic resonance imaging (MRI) characteristics in a porcine spinal cord injury model. Six adult minipigs weighing…”
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Neuropathic pain is associated with alterations of nitric oxide synthase immunoreactivity and catalytic activity in dorsal root ganglia and spinal dorsal horn
Published in Brain research bulletin (01-06-2002)“…Previous experiments have suggested that nitric oxide may play an important role in nociceptive transmission in the spinal cord. To assess the possible roles…”
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Repeated Baclofen treatment ameliorates motor dysfunction, suppresses reflex activity and decreases the expression of signaling proteins in reticular nuclei and lumbar motoneurons after spinal trauma in rats
Published in Acta histochemica (01-03-2014)“…The interruption of supraspinal input to the spinal cord leads to motor dysfunction and the development of spasticity. Clinical studies have shown that…”
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Spinal cord transection modifies neuronal nitric oxide synthase expression in medullar reticular nuclei and in the spinal cord and increases parvalbumin immunopositivity in motoneurons below the site of injury in experimental rabbits
Published in Acta histochemica (01-09-2012)“…Using immunohistochemistry, we detected the expression of neuronal nitric oxide synthase (nNOS) in ventral medullary gigantocellular reticular nuclei and in…”
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The evidence for nitric oxide synthase immunopositivity in the monosynaptic Ia-motoneuron pathway of the dog
Published in Experimental neurology (01-09-2005)“…In this study, nitric oxide synthase immunohistochemistry supported by nicotinamide adenine dinucleotide phosphate diaphorase histochemistry was used to…”
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Identification of NO/sGC signalling in the bulbospinal respiratory pathway after C2–C3 hemisection of the spinal cord in rats
Published in Acta histochemica (01-11-2011)“…Guanylyl cyclase (GC) as the effector molecule for nitric oxide (NO) plays a key role in the NO/cGMP signalling cascade. Based on these observations, our study…”
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The regional distribution of nitric oxide synthase activity in the spinal cord of the dog
Published in Brain research bulletin (01-06-2002)“…The aim of this study was to examine the distribution of calcium-dependent nitric oxide synthase activity (cNOS) in the white and gray matter in cervical,…”
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