Search Results - "Lujan, Hugo"

Antigenic variation in Giardia lamblia is regulated by RNA interference by Prucca, César G, Elías, Eliana V, Luján, Hugo D, Rivero, Fernando D, Slavin, Ileana, Saura, Alicia, Quiroga, Rodrigo, Carranza, Pedro G

“…Giardia lamblia (also called Giardia intestinalis ) is one of the most common intestinal parasites of humans. To evade the host’s immune response, Giardia…”
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Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia by Carranza, Pedro G., Gargantini, Pablo R., Prucca, César G., Torri, Alessandro, Saura, Alicia, Svärd, Staffan, Lujan, Hugo D.

“…•The early-branching eukaryote Giardia lamblia shows the most common histone marks.•Histone deacetylation is particularly relevant for Giardia differentiation…”
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Regulation of Antigenic Variation in Giardia lamblia by Prucca, César G, Rivero, Fernando D, Luján, Hugo D

“…Antigenic variation, a clonal phenotypic variation developed by microorganisms, involves the permanent switching of homologous, antigenically different cell…”
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New insights regarding the biology of Giardia lamblia by Carranza, Pedro G., Lujan, Hugo D.

“…Giardia lamblia is one of the most common causes of intestinal disease in humans. To adapt to environments both inside and outside of the host's small…”
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Antigenic variation in Giardia lamblia by Prucca, Cesar G, Lujan, Hugo D

“…Giardia lamblia undergoes antigenic variation, both in vitro and within the intestines of infected individuals. Variant-specific surface proteins (VSPs) cover…”
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Unveiling the immune infiltrate modulation in cancer and response to immunotherapy by MIXTURE—an enhanced deconvolution method by Fernández, Elmer A, Mahmoud, Yamil D, Veigas, Florencia, Rocha, Darío, Miranda, Matías, Merlo, Joaquín, Balzarini, Mónica, Lujan, Hugo D, Rabinovich, Gabriel A, Girotti, María Romina

“…Abstract The accurate quantification of tumor-infiltrating immune cells turns crucial to uncover their role in tumor immune escape, to determine patient…”
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Trying to get rid of protozoan parasites by Lujan, Hugo D

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Disruption of antigenic variation is crucial for effective parasite vaccine by Lujan, Hugo D, Rivero, Fernando D, Saura, Alicia, Prucca, Cesar G, Carranza, Pedro G, Torri, Alessandro

“…Giardia lamblia is a major intestinal pathogen causing acute or chronic diarrhea. It is thought to evade the immune system by switching its expression of the…”
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Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses by Velasquez, Lis Noelia, Stüve, Philipp, Gentilini, Maria Virginia, Swallow, Maxine, Bartel, Judith, Lycke, Nils Yngve, Barkan, Daniel, Martina, Mariana, Lujan, Hugo D, Kalay, Hakan, van Kooyk, Yvette, Sparwasser, Tim D, Berod, Luciana

“…Tuberculosis remains a major global health problem and efforts to develop a more effective vaccine have been unsuccessful so far. Targeting antigens (Ags) to…”
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Mechanisms of adaptation in the intestinal parasite Giardia lamblia by Lujan, Hugo D

“…Giardia lamblia, a parasite of humans, is a major source of waterborne diarrhoeal disease. Giardia is also an excellent system to study basic biochemical…”
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Putative SF2 helicases of the early-branching eukaryote Giardia lamblia are involved in antigenic variation and parasite differentiation into cysts by Gargantini, Pablo R, Serradell, Marianela C, Torri, Alessandro, Lujan, Hugo D

“…Regulation of surface antigenic variation in Giardia lamblia is controlled post-transcriptionally by an RNA-interference (RNAi) pathway that includes a…”
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In silico analysis of trypanosomatids' helicases by Gargantini, Pablo R., Lujan, Hugo D., Pereira, Claudio A.

“…Abstract Trypanosomatids are unicellular protozoan parasites that cause many diseases in animals, including humans, and plants. These early divergent…”
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The ubiquitin-activating enzyme (E1) of the early-branching eukaryote Giardia intestinalis shows unusual proteolytic modifications and play important roles during encystation by Niño, Carlos A., Prucca, Cesar G., Chaparro, Jenny, Luján, Hugo D., Wasserman, Moisés

“…The E1 family characteristics domains are present in the E1 protein of Giardia intestinalis; the lower panel shows the E1 localization pattern in trophozoites…”
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Active and Passive Mechanisms Drive Secretory Granule Biogenesis during Differentiation of the Intestinal Parasite Giardia lamblia by Gottig, Natalia, Elías, Eliana V., Quiroga, Rodrigo, Nores, María J., Solari, Alberto J., Touz, María C., Luján, Hugo D.

“…The parasitic protozoan Giardia lamblia undergoes important changes to survive outside the intestine of its host by differentiating into infective cysts…”
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Functional characterization of methionine sulfoxide reductase A from Trypanosoma spp by Arias, Diego G., Cabeza, Matías S., Erben, Esteban D., Carranza, Pedro G., Lujan, Hugo D., Téllez Iñón, María T., Iglesias, Alberto A., Guerrero, Sergio A.

“…Methionine is an amino acid susceptible to being oxidized to methionine sulfoxide (MetSO). The reduction of MetSO to methionine is catalyzed by methionine…”
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Vaccination of domestic animals with a novel oral vaccine prevents Giardia infections, alleviates signs of giardiasis and reduces transmission to humans by Serradell, Marianela C, Saura, Alicia, Rupil, Lucia L, Gargantini, Pablo R, Faya, Marcela I, Furlan, Paulina J, Lujan, Hugo D

“…Giardia lamblia is a human intestinal parasite and one of the most frequent enteric pathogen of companion animals. Clinical manifestations of giardiasis, such…”
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Characterization of SNAREs Determines the Absence of a Typical Golgi Apparatus in the Ancient Eukaryote Giardia lamblia by Elias, Eliana V., Quiroga, Rodrigo, Gottig, Natalia, Nakanishi, Hideki, Nash, Theodore E., Neiman, Aaron, Lujan, Hugo D.

“…Giardia is a eukaryotic protozoal parasite with unusual characteristics, such as the absence of a morphologically evident Golgi apparatus. Although both…”
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Immunolocalization and enzymatic functional characterization of the thioredoxin system in Entamoeba histolytica by Arias, Diego G., Carranza, Pedro G., Lujan, Hugo D., Iglesias, Alberto A., Guerrero, Sergio A.

“…The components of the redox metabolism in Entamoeba histolytica have been recently revisited by Arias et al. ( Free Radic. Biol. Med. 42:1496–1505; 2007),…”
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Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins by Serradell, Marianela C., Rupil, Lucía L., Martino, Román A., Prucca, César G., Carranza, Pedro G., Saura, Alicia, Fernández, Elmer A., Gargantini, Pablo R., Tenaglia, Albano H., Petiti, Juan P., Tonelli, Renata R., Reinoso-Vizcaino, Nicolás, Echenique, José, Berod, Luciana, Piaggio, Eliane, Bellier, Bertrand, Sparwasser, Tim, Klatzmann, David, Luján, Hugo D.

“…Intestinal and free-living protozoa, such as Giardia lamblia , express a dense coat of variant-specific surface proteins (VSPs) on trophozoites that protects…”
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Small Sense and Antisense RNAs Derived from a Telomeric Retroposon Family in Giardia intestinalis by Ullu, Elisabetta, Lujan, Hugo D, Tschudi, Christian

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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