Search Results - "Luisa Laorden, María"
-
1
Cardiac Changes in Parkinson's Disease: Lessons from Clinical and Experimental Evidence
Published in International journal of molecular sciences (16-12-2021)“…Dysautonomia is a common non-motor symptom in Parkinson's disease (PD). Most dysautonomic symptoms appear due to alterations in the peripheral nerves of the…”
Get full text
Journal Article -
2
Could Small Heat Shock Protein HSP27 Be a First-Line Target for Preventing Protein Aggregation in Parkinson's Disease?
Published in International journal of molecular sciences (16-03-2021)“…Small heat shock proteins (HSPs), such as HSP27, are ubiquitously expressed molecular chaperones and are essential for cellular homeostasis. The major…”
Get full text
Journal Article -
3
Cardiac tyrosine hydroxylase activation and MB-COMT in dyskinetic monkeys
Published in Scientific reports (06-10-2021)“…The impact of age-associated disorders is increasing as the life expectancy of the population increments. Cardiovascular diseases and neurodegenerative…”
Get full text
Journal Article -
4
Cardiac Noradrenaline Turnover and Heat Shock Protein 27 Phosphorylation in Dyskinetic Monkeys
Published in Movement disorders (01-04-2020)“…Background Autonomic dysfunction is a well‐known dominant symptom in the advanced stages of Parkinson's disease. However, the role of cardiac sympathetic…”
Get full text
Journal Article -
5
Pharmacological modulation of the behavioral effects of social defeat in memory and learning in male mice
Published in Psychopharmacology (01-09-2019)“…Rationale Previous studies have demonstrated that repeated social defeat (RSD) stress only induces cognitive deficits when experienced during adulthood…”
Get full text
Journal Article -
6
Cut-off value for β-trace protein (β-TP) as a rapid diagnostic of cerebrospinal fluid (CSF) leak detection
Published in Laryngoscope investigative otolaryngology (01-10-2023)“…To find an adequate cut-off point for beta trace protein (β-TP) in nasal secretion (NS) and validate this diagnostic test with a large sample of patients…”
Get full text
Journal Article -
7
Naloxone-induced conditioned place aversion score and extinction period are higher in C57BL/6J morphine-dependent mice than in Swiss: Role of HPA axis
Published in Pharmacology, biochemistry and behavior (01-02-2021)“…Intense associative memories develop between drug-paired contextual cues and the drug withdrawal associated aversive feeling. They have been suggested to…”
Get full text
Journal Article -
8
Repeated social defeat and the rewarding effects of cocaine in adult and adolescent mice: dopamine transcription factors, proBDNF signaling pathways, and the TrkB receptor in the mesolimbic system
Published in Psychopharmacology (01-07-2017)“…Rationale Repeated social defeat (RSD) increases the rewarding effects of cocaine in adolescent and adult rodents. Objective The aim of the present study was…”
Get full text
Journal Article -
9
Binge ethanol and MDMA combination exacerbates HSP27 and Trx-1 (biomarkers of toxic cardiac effects) expression in right ventricle
Published in Life sciences (1973) (01-03-2019)“…Oxidative stress caused by exposure to drugs of abuse such as ethanol or 3, 4 methylenedioxymethamphetamine (MDMA) may derive from direct or indirect effects…”
Get full text
Journal Article -
10
Cardiac Protective Role of Heat Shock Protein 27 in the Stress Induced by Drugs of Abuse
Published in International journal of molecular sciences (21-05-2020)“…Heat shock proteins (HSP) are induced after different stress situations. Some of these proteins, particularly HSP-27, function as markers to indicate cellular…”
Get full text
Journal Article -
11
Binge Ethanol and MDMA Combination Exacerbates Toxic Cardiac Effects by Inducing Cellular Stress
Published in PloS one (28-10-2015)“…Binge drinking is a common pattern of ethanol consumption among young people. Binge drinkers are especially susceptible to brain damage when other substances…”
Get full text
Journal Article -
12
Role of CRF1 receptor in post-incisional plasma extravasation and nociceptive responses in mice
Published in Toxicology and applied pharmacology (01-10-2017)“…The corticotropin-releasing factor (CRF) is involved in a number of physiological functions including pain perception. The purpose of this study was to…”
Get full text
Journal Article -
13
Expression of heat shock protein 27 and troponin T and troponin I after naloxone-precipitated morphine withdrawal
Published in European journal of pharmacology (05-11-2015)“…Heat shock protein (Hsp27) renders cardioprotection from stress situations but little is known about its role in myofilaments. In this study we have evaluated…”
Get full text
Journal Article -
14
Sex differences between CRF1 receptor deficient mice following naloxone-precipitated morphine withdrawal in a conditioned place aversion paradigm: implication of HPA axis
Published in PloS one (01-04-2015)“…Extinction period of positive affective memory of drug taking and negative affective memory of drug withdrawal, as well as the different response of men and…”
Get full text
Journal Article -
15
Corticotropin‐releasing factor (CRF) receptor‐1 is involved in cardiac noradrenergic activity observed during naloxone‐precipitated morphine withdrawal
Published in British journal of pharmacology (01-02-2014)“…Background and Purpose The negative affective states of withdrawal involve the recruitment of brain and peripheral stress circuitry [noradrenergic activity,…”
Get full text
Journal Article -
16
CP-154,526 Modifies CREB Phosphorylation and Thioredoxin-1 Expression in the Dentate Gyrus following Morphine-Induced Conditioned Place Preference
Published in PloS one (27-08-2015)“…Corticotropin-releasing factor (CRF) acts as neuro-regulator of the behavioral and emotional integration of environmental and endogenous stimuli associated…”
Get full text
Journal Article -
17
Role of corticotropin-releasing factor (CRF) receptor-1 on the catecholaminergic response to morphine withdrawal in the nucleus accumbens (NAc)
Published in PloS one (10-10-2012)“…Stress induces the release of the peptide corticotropin-releasing factor (CRF) into the ventral tegmental area (VTA), and also increases dopamine (DA) levels…”
Get full text
Journal Article -
18
Sympathetic activity induced by naloxone-precipitated morphine withdrawal is blocked in genetically engineered mice lacking functional CRF1 receptor
Published in Toxicology and applied pharmacology (15-02-2015)“…There is large body evidence indicating that stress can lead to cardiovascular disease. However, the exact brain areas and the mechanisms involved remain to be…”
Get full text
Journal Article -
19
Brain stress system response after morphine-conditioned place preference
Published in The international journal of neuropsychopharmacology (01-10-2013)“…This study examined the involvement of the brain stress system in the reinforcing effects of morphine. One group of mice was conditioned to morphine using the…”
Get full text
Journal Article -
20
Correction: Role of Corticotropin-Releasing Factor (CRF) Receptor-1 on the Catecholaminergic Response to Morphine Withdrawal in the Nucleus Accumbens (NAc)
Published in PloS one (17-05-2013)“…The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (2013) Correction: Role of…”
Get full text
Journal Article